🎧 New: AI-Generated Podcasts Turn your study notes into engaging audio conversations. Learn more

Neuromuscular Blockers and Skeletal Muscle Relaxants Quiz
24 Questions
0 Views

Neuromuscular Blockers and Skeletal Muscle Relaxants Quiz

Created by
@ExaltingVictory

Podcast Beta

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What are the two types of skeletal muscle relaxants mentioned in the text?

Neuromuscular blockers and Spasmolytic Drugs

What are the subtypes of Neuromuscular blockers?

Non-depolarizing (Competitive) blockers and Depolarizing blockers

What are the uses of Neuromuscular blockers?

Surgical procedures, ICU, general anesthesia, tracheal intubation

What are the uses of Spasmolytic Drugs?

<p>Chronic back pain, painful fibromyalgias</p> Signup and view all the answers

What is the mechanism of action of Non-depolarizing (Competitive) blockers?

<p>Reversible competitive antagonists</p> Signup and view all the answers

Name the prototype of Non-depolarizing (Competitive) blockers.

<p>d-tubocurarine</p> Signup and view all the answers

What is the second type of blockade mentioned in the text?

<p>Depolarizing type</p> Signup and view all the answers

Name the prototype of Depolarizing blockers.

<p>Succinylcholine</p> Signup and view all the answers

What are the two sequential events of Depolarizing block?

<p>Phase 1 (depolarization block) and Phase 2 (desensitization block)</p> Signup and view all the answers

What is the effect of Succinylcholine on NMJ and autonomic ganglia?

<p>More effect on NMJ and less on autonomic ganglia</p> Signup and view all the answers

What is the order of paralysis caused by Depolarizing Blockers?

<p>Neck, limbs, face, jaws, eyes, pharynx, trunk, respiratory</p> Signup and view all the answers

What are the adverse drug reactions (ADRs) of Nondepolarizing Blockers?

<p>Respiratory paralysis, Hyperkalemia, Malignant hyperthermia</p> Signup and view all the answers

What are the reversible anti-AChE agents that can reverse the block caused by nondepolarizing blockers?

<p>Neostigmine, pyridostigmine</p> Signup and view all the answers

What can potentiate the effects of nondepolarizing blockers?

<p>Hypokalemia</p> Signup and view all the answers

What group of individuals are sensitive to nondepolarizing blockers?

<p>Newborn and myasthenia patients</p> Signup and view all the answers

Name two adverse effects of nondepolarizing blockers.

<p>Bronchospasm, hypotension</p> Signup and view all the answers

What is the potentiation effect of inhalational anesthetics on nondepolarizing blockers?

<p>Potentiation</p> Signup and view all the answers

Name the nondepolarizing blocker that is 5 times more potent than d-tubocurarine.

<p>Pancuronium</p> Signup and view all the answers

What is the onset time and duration of action of atracurium?

<p>Onset - 2.9 minutes, Duration of action - 110 minutes</p> Signup and view all the answers

What is the rapid onset time and duration of action of rocuronium?

<p>Onset - 1 minute, Duration of action - 55 minutes</p> Signup and view all the answers

What is the onset time and duration of action of mivacurium?

<p>Onset - 1.8 minutes, Duration of action - 20 minutes</p> Signup and view all the answers

Name 3 uses of neuromuscular blocking drugs.

<p>Surgical relaxation, tracheal intubation, control of ventilation</p> Signup and view all the answers

What is the MOA of baclofen, a centrally acting spasmolytic drug?

<p>GABAB agonist causing membrane hyper-polarization via increased K+ conductance</p> Signup and view all the answers

What is the MOA of diazepam, a centrally acting spasmolytic drug?

<p>Facilitates GABAergic transmission in the central nervous system, increases interneuron inhibition of primary motor afferents in spinal cord</p> Signup and view all the answers

Use Quizgecko on...
Browser
Browser