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Questions and Answers
What are the primary functions of the autonomic nervous system?
What are the primary functions of the autonomic nervous system?
The primary functions include controlling heartbeat, breathing, digestion, and body temperature.
What type of signaling is associated with afferent and efferent nerves?
What type of signaling is associated with afferent and efferent nerves?
Afferent nerves carry sensory information to the central nervous system, while efferent nerves transmit signals from the CNS to effectors like muscles.
Describe the role of glial cells in the nervous system.
Describe the role of glial cells in the nervous system.
Glial cells support and protect neurons, assisting in the maintenance of homeostasis and forming myelin.
What is the difference between multipolar, unipolar, and bipolar neurons?
What is the difference between multipolar, unipolar, and bipolar neurons?
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What is synaptic transmission and why is it important?
What is synaptic transmission and why is it important?
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What is the resting membrane potential and its typical value in neurons?
What is the resting membrane potential and its typical value in neurons?
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Explain the role of potassium (K+) ions in generating the resting membrane potential.
Explain the role of potassium (K+) ions in generating the resting membrane potential.
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What is the function of ependymal cells in the central nervous system?
What is the function of ependymal cells in the central nervous system?
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How do microglia contribute to the immune response in the nervous system?
How do microglia contribute to the immune response in the nervous system?
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What factors contribute to the steady state of the resting membrane potential?
What factors contribute to the steady state of the resting membrane potential?
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What are the primary roles of glial cells in the nervous system?
What are the primary roles of glial cells in the nervous system?
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Identify two types of neurons found in the central nervous system (CNS) and their primary functions.
Identify two types of neurons found in the central nervous system (CNS) and their primary functions.
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What role do oligodendrocytes play in the nervous system?
What role do oligodendrocytes play in the nervous system?
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Contrast the functions of astrocytes in the CNS and satellite cells in the PNS.
Contrast the functions of astrocytes in the CNS and satellite cells in the PNS.
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What is the significance of the blood-brain barrier (BBB) in relation to astrocytes?
What is the significance of the blood-brain barrier (BBB) in relation to astrocytes?
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Study Notes
Nervous Tissue 1
- Nervous tissue is the functional unit of the nervous system
- Neurons are specialized cells that transmit electrical impulses
- Neurons share common structural features to send and receive information
- Nervous tissue has multiple functions including autonomic functions (heartbeat, breathing, etc), cognitive skills (planning, thinking), and sensorimotor function (sensation and movement)
- There are different structural neuron types, including multipolar, pseudo-unipolar, bipolar, and anaxomic neurons
- Examples of specific neuron types and functions include motor neurons, pyramidal cells, mitral cells, and Purkinje cells
- Glial cells support and maintain the function of neurons, including astrocytes, oligodendrocytes, microglia, and Schwann cells
Nerve Conduction
- The resting membrane potential is -70mV
- Ionic concentrations at rest create an extracellular environment that has a net positive charge, an intracellular environment with negative charge and creates a membrane charge of minus 70mV
- Stimulus initiates an influx of positively charged ions, changing the membrane voltage in a process called depolarization, to a positive value
- Repolarization returns a cell to its resting membrane potential
- Action potentials are an "all-or-nothing" response
- Propagation of action potential, starting at the axon hillock, and moving as a wave along the axon, due to the voltage-gated Na+ channels producing a regenerative current
Synaptic Transmission
- An AP reaching the axon terminal stimulates calcium channels to open
- Ca2+ causes synaptic vesicles to release neurotransmitter molecules
- Molecules diffuse across the synaptic cleft, binding to receptors
- The binding of neurotransmitter to receptors opens Na+ channels, generating a postsynaptic potential
- Active reuptake of remaining neurotransmitter is involved
Summation
- Simultaneous stimuli from several conducting fibers is called spatial summation
- Successive stimuli on the same nerve is called temporal summation
Peripheral Nerves, Spinal Nerves, and Dermatomes & Myotomes
- Peripheral nerves are categorized by afferent and efferent signaling
- Mixed spinal nerves contain both afferent and efferent fibers
- Nerve plexus are networks of intersecting nerves
- Dermatomes are specific areas of skin supplied by a single spinal nerve
- Myotomes are muscles supplied by a single spinal nerve
Glial Cells
- Glial cells support and maintain the function of neurons in the nervous system, they are non-excitable cells, supporting the survival and function of the nervous system
- Examples of glial cells include astrocytes, oligodendrocytes, microglia, satellite cells, Schwann cells, and ependymal cells
Myelin Sheath and Conduction Velocity
- Myelin is a fatty substance that insulates axons, preventing ion leakage
- Myelination increases the resistance of the axon membrane
- In myelinated axons, action potentials "jump" from node to node (saltatory conduction), significantly increasing conduction velocity
- Axon diameter and temperature are also factors affecting conduction velocity, larger diameters and higher temperatures generally increase nerve conduction velocity, due to the quicker diffusion of ions
Blood-Brain Barrier
- The blood-brain barrier (BBB) is a selectively permeable barrier that controls which molecules can pass between the blood and nervous tissue
- The BBB is made up of specialized endothelial cells, tight junctions, and astrocytes, together forming a barrier that limit the passage of substances from the blood into the brain.
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Description
Test your knowledge on nervous tissue and nerve conduction with this quiz. Explore the various types of neurons, their functions, and the underlying principles of nerve impulses and resting membrane potential. Perfect for students of neuroscience and biology.