Podcast
Questions and Answers
Which part of the autonomic nervous system is responsible for mobilizing body systems during activity?
Which part of the autonomic nervous system is responsible for mobilizing body systems during activity?
What is the primary function of the parasympathetic division of the autonomic nervous system?
What is the primary function of the parasympathetic division of the autonomic nervous system?
Which type of nerve fibers conducts impulses from the CNS to cardiac muscles?
Which type of nerve fibers conducts impulses from the CNS to cardiac muscles?
What defines the difference between the somatic nervous system and the autonomic nervous system?
What defines the difference between the somatic nervous system and the autonomic nervous system?
Signup and view all the answers
Which part of the nervous system includes the brain and spinal cord?
Which part of the nervous system includes the brain and spinal cord?
Signup and view all the answers
What type of nerve fibers are included in the sensory division of the peripheral nervous system?
What type of nerve fibers are included in the sensory division of the peripheral nervous system?
Signup and view all the answers
Which division of the autonomic nervous system is primarily active during rest?
Which division of the autonomic nervous system is primarily active during rest?
Signup and view all the answers
In which division of the nervous system would you find motor fibers conducting impulses to effectors?
In which division of the nervous system would you find motor fibers conducting impulses to effectors?
Signup and view all the answers
Which muscles are directly innervated by the fibers of the sympathetic division of the autonomic nervous system?
Which muscles are directly innervated by the fibers of the sympathetic division of the autonomic nervous system?
Signup and view all the answers
Which part of the nervous system is chiefly responsible for communication between the CNS and the rest of the body?
Which part of the nervous system is chiefly responsible for communication between the CNS and the rest of the body?
Signup and view all the answers
What characteristic distinguishes the axon hillock from the dendrites?
What characteristic distinguishes the axon hillock from the dendrites?
Signup and view all the answers
Which of the following correctly describes the function of Nissl bodies in the nerve cell body?
Which of the following correctly describes the function of Nissl bodies in the nerve cell body?
Signup and view all the answers
What is true about myelinated axons in the central nervous system (CNS) compared to those in the peripheral nervous system (PNS)?
What is true about myelinated axons in the central nervous system (CNS) compared to those in the peripheral nervous system (PNS)?
Signup and view all the answers
Which of the following statements best describes the functional role of dendrites in a neuron?
Which of the following statements best describes the functional role of dendrites in a neuron?
Signup and view all the answers
Which of the following statements about the nerve cell body is NOT true?
Which of the following statements about the nerve cell body is NOT true?
Signup and view all the answers
Which cell type is primarily responsible for maintaining the blood-brain barrier?
Which cell type is primarily responsible for maintaining the blood-brain barrier?
Signup and view all the answers
What is the primary role of oligodendrocytes in the central nervous system?
What is the primary role of oligodendrocytes in the central nervous system?
Signup and view all the answers
Which type of neuroglia acts as phagocytes that keep an eye on neuron health?
Which type of neuroglia acts as phagocytes that keep an eye on neuron health?
Signup and view all the answers
Which of the following is NOT a function of astrocytes?
Which of the following is NOT a function of astrocytes?
Signup and view all the answers
What distinguishes Schwann cells from oligodendrocytes?
What distinguishes Schwann cells from oligodendrocytes?
Signup and view all the answers
Which type of neuroglia is capable of regulating the environment around neuron cell bodies in the ganglia?
Which type of neuroglia is capable of regulating the environment around neuron cell bodies in the ganglia?
Signup and view all the answers
What happens to the myelin sheath in Multiple Sclerosis?
What happens to the myelin sheath in Multiple Sclerosis?
Signup and view all the answers
Which of the following statements regarding neuroglia is true?
Which of the following statements regarding neuroglia is true?
Signup and view all the answers
What occurs during the depolarization phase of an action potential?
What occurs during the depolarization phase of an action potential?
Signup and view all the answers
What is the primary function of the sodium-potassium pump during the action potential?
What is the primary function of the sodium-potassium pump during the action potential?
Signup and view all the answers
Which statement accurately describes the process of repolarization?
Which statement accurately describes the process of repolarization?
Signup and view all the answers
What distinguishes continuous propagation from saltatory propagation in action potentials?
What distinguishes continuous propagation from saltatory propagation in action potentials?
Signup and view all the answers
What primarily generates the resting membrane potential in a neuron?
What primarily generates the resting membrane potential in a neuron?
Signup and view all the answers
Which statement is correct regarding the sodium-potassium pump's function?
Which statement is correct regarding the sodium-potassium pump's function?
Signup and view all the answers
How does an electrochemical gradient influence ion movement?
How does an electrochemical gradient influence ion movement?
Signup and view all the answers
Why is the inside of a neuron negatively charged during resting potential?
Why is the inside of a neuron negatively charged during resting potential?
Signup and view all the answers
Which of the following describes voltage-gated channels?
Which of the following describes voltage-gated channels?
Signup and view all the answers
What is the role of mechanically gated channels in neurons?
What is the role of mechanically gated channels in neurons?
Signup and view all the answers
What determines the resting membrane potential value in neurons?
What determines the resting membrane potential value in neurons?
Signup and view all the answers
What is the significance of the negative sign in the resting membrane potential value?
What is the significance of the negative sign in the resting membrane potential value?
Signup and view all the answers
Which statement about unmyelinated axons is accurate?
Which statement about unmyelinated axons is accurate?
Signup and view all the answers
What primarily composes gray matter?
What primarily composes gray matter?
Signup and view all the answers
Which neuron type is the most abundant in the central nervous system?
Which neuron type is the most abundant in the central nervous system?
Signup and view all the answers
What is the primary function of sensory (afferent) neurons?
What is the primary function of sensory (afferent) neurons?
Signup and view all the answers
What characterizes the action potentials in neurons?
What characterizes the action potentials in neurons?
Signup and view all the answers
Which of the following statements about ion channels is incorrect?
Which of the following statements about ion channels is incorrect?
Signup and view all the answers
What is the primary role of oligodendrocytes in the CNS?
What is the primary role of oligodendrocytes in the CNS?
Signup and view all the answers
What distinguishes a unipolar neuron from other types?
What distinguishes a unipolar neuron from other types?
Signup and view all the answers
Study Notes
Nervous System Objectives
- Describe the divisions of the nervous system and their characteristics.
- Identify the structures and functions of a typical neuron.
- Describe the location and function of neuroglia.
- Describe resting membrane potentials.
- Discuss the events in the generation and propagation of an action potential.
- Define the structure and function of a synapse.
Nervous System
- The master controlling and communicating system of the body.
- Functions:
- Sensory input - stimuli goes to the CNS.
- Integration - interpretation of sensory input.
- Motor output - response to stimuli coming from the CNS.
Terminology
-
Input (Sensory):
- Receptors monitor changes.
- Changes are called stimuli.
- Information is sent by afferent nerves.
-
Integration:
- Information is processed.
- A decision is made about what should be done.
-
Output (Motor):
- Effector organs (muscles or glands) are activated.
- Effected by efferent nerves.
Organization of the Nervous System
-
Central nervous system (CNS):
- Brain and spinal cord.
- Integration and command center.
-
Peripheral nervous system (PNS):
- Paired spinal and cranial nerves.
- Carries messages to and from the spinal cord and brain.
Peripheral Nervous System (PNS): Two Functional Divisions
-
1. Sensory (afferent) division:
- Somatic sensory fibers - carry impulses from skin, skeletal muscles, and joints to the brain.
- Visceral sensory fibers - transmit impulses from visceral organs to the brain.
-
2. Motor (efferent) division:
- Carries impulses from the CNS to effector organs (muscles and glands).
Motor Division: Two Main Parts
-
1. Somatic Nervous System:
- Voluntary - carry impulses from the CNS to skeletal muscles.
-
2. Autonomic Nervous System (ANS):
- Involuntary - carry impulses from the CNS to smooth muscle, cardiac muscle, and glands.
ANS Division: Two Main Parts
- Sympathetic and Parasympathetic.
Histology of Nerve Tissue
- The two principal cell types of the nervous system are neurons and neuroglia (glial).
- Neurons: Excitable cells that transmit electrical signals.
- Neuroglia (glial): Cells that surround and wrap neurons (supporting cells).
Supporting Cells: Neuroglia
- Provide a supportive scaffolding for neurons.
- Segregate and insulate neurons.
- Guide young neurons to the proper connections.
- Promote neuron health and growth.
- Six types: 4 in CNS, 2 in PNS.
Neuroglia of the CNS
-
Astrocytes:
- Most abundant, versatile, and highly branched glial cells.
- Maintain blood-brain barrier.
- Cling to neurons and their synaptic endings.
- Wrap around capillaries, regulating their permeability.
- Provide structural framework for the neuron.
- Guide migration of young neurons.
- Control the chemical environment.
- Repair damaged neural tissue
-
Microglia: Small, ovoid cells with spiny processes.
- Phagocytes that monitor the health of neurons.
-
Ependymal cells: Range in shape from squamous to columnar.
- Line the central cavities of the brain and spinal column.
-
Oligodendrocytes: Branched cells with myelin.
- Myelin: Wraps oligodendrocyte processes around nerve fibers
- Insulates nerve fibers.
Neuroglia of the PNS
-
Schwann cells (neurolemmocytes):
- Myelin: Wraps itself around nerve fibers, insulating them.
- Satellite cells: Surround neuron cell bodies in ganglia, regulating the environment around the neurons.
Myelin in the Peripheral and Central Nervous Systems
- Myelin sheaths can either be formed by Schwann cells (PNS), or by oligodendrocytes (CNS).
Action Potentials (APs)
- Brief reversal of membrane potential, only generated by muscle cells and neurons.
- Do not decrease in strength over distance.
- Principal means of neural communication.
- An action potential in the axon of a neuron is a nerve impulse.
Action Potential: Resting State
- Na+ and K+ channels are closed.
Action Potential: Depolarization Phase
- Na+ permeability increases, membrane potential reverses. Na+ gates open; K+ gates close.
- Threshold: critical level of depolarization (-55 to -50 mV). Depolarization becomes self-generating at threshold.
Action Potential: Repolarization Phase
- Sodium inactivation gates close; membrane permeability to Na+ declines to resting levels.
- Voltage-sensitive K+ gates open; K+ exits the cell.
- Internal negativity of the resting neuron is restored.
Action Potential: Hyperpolarization
- Potassium gates remain open, causing an excessive efflux of K+.
- This efflux causes hyperpolarization of the membrane (undershoot).
- The neuron is insensitive to stimulus and depolarization during this time.
Action Potential: Role of the Sodium-Potassium Pump
- Restores resting electrical conditions of the neuron, but does not restore the resting ionic conditions.
Propagation of an Action Potential:
- Continuous and Saltatory Propagation
- Continuous: Unmyelinated axons, current flows across the entire membrane.
- Saltatory: Myelinated axons, current jumps between Nodes of Ranvier.
- Action potential only generated at the Nodes of Ranvier.
Types of Stimuli
- Threshold Stimulus: Strong enough to bring the membrane potential to a threshold voltage, causing an action potential.
- Subthreshold Stimulus: Weak stimuli that cause depolarization (graded potentials), but not action potentials.
Coding for Stimulus Intensity
- Action potentials are all-or-none; strong stimuli generate action potentials more often than weaker ones.
- The CNS determines stimulus intensity by the frequency of impulse transmission.
Absolute Refractory Period
- Time from Na+ activation gates opening to inactivation gates closing.
- Prevents the neuron from generating another action potential ensuring separate action potentials.
- Enforces one-way transmission of nerve impulses.
Relative Refractory Period
- Interval following the absolute refractory period; Sodium gates are closed, potassium gates are open, and repolarization is occurring.
Synapse
- The means by which adjacent neurons communicate.
- Most synapses occur between the axon of one neuron and the dendrites of another (axodendritic) or between the axon of one neuron and the cell body of another (axosomatic).
- The presynaptic neuron sends information, and the postsynaptic neuron receives it.
- Neurons may have 1000 to 10000 axonal terminals making synapses.
Grey and White Matter
- Grey Matter: Consists of unsheathed nerve fibers, cannot be regenerated if damaged (in cortex or surface layer).
- White Matter: Makes up the internal structures and consists of myelinated nerve fibers. The brain and spinal cord receive impulses, process the information, and respond with the appropriate action.
Electrical Synapses
- Less common than chemical synapses.
- Correspond to gap junctions found in other cell types.
- Very fast propagation of action potentials.
- Important in the CNS for arousal from sleep, mental attention, emotions, and memory.
- Important for ion and water homeostasis.
Chemical Synapses
- Specialized for the release and reception of neurotransmitters.
- Composed of presynaptic and postsynaptic neurons.
- Presynaptic Neuron: Contains synaptic vesicles, which release neurotransmitters across the synaptic cleft to the postsynaptic neuron.
- Postsynaptic Neuron: Receptors are located on dendrites and soma.
Chemical Synapses: Other Features
- Synaptic cleft: Fluid-filled space separating the neurons; transmission is a chemical event, unlike the electrical one.
- Synaptic cleft: Information Transfer: Nerve impulses reach the axon terminal of the presynaptic neuron, open Ca2+ channels. Neurotransmitter is released into the synaptic cleft via exocytosis. Neurotransmitter crosses the synaptic cleft and binds to receptors on the postsynaptic neuron; postsynaptic membrane permeability changes, causing excitatory or inhibitory effect.
Termination of Neurotransmitter Effects
- Neurotransmitter bound to a postsynaptic neuron produces a continuous postsynaptic effect, blocking reception of additional messages. Must be removed from its receptor.
Postsynaptic Potentials
- Neurotransmitter receptors mediate changes in membrane potential according to the amounts of neurotransmitter released and the time the neurotransmitter is bound to receptors.
- Types:
- EPSPs: Excitatory postsynaptic potentials. Cause depolarization, increasing likelihood of action potential.
- IPSPs: Inhibitory postsynaptic potentials. Cause hyperpolarization, reducing likelihood of action potential.
Terminology for Quiz
- Neuron: nerve cell
- Neuroglia: supporting cell
- Nerve fiber: long axon
- Nerve: collection of axons in PNS
- Tract: collection of axons in CNS
- Nucleus: cluster of cell bodies in CNS
- Ganglia: cluster of cell bodies in PNS
- Unilateral: one side
- Ipsilateral: same side
- Contralateral: opposite side
- CNS: Central Nervous System
- PNS: Peripheral Nervous System
- Input/sensory: afferent; to brain
- Output/motor: efferent; from brain
Examine Yourself
- Neurons: inside/outside CNS
- Structures concerned with CSF formation: arachnoid villi, choroid plexus, subdural space, dural venous sinus
- Peripheral nervous system involves: spinal ganglia, spinal cord, brain, tracts
- Lateral ventricle lies in: cerebrum, diencephalon, midbrain, cerebellum
References
- Information was compiled from multiple referenced sources; it is impossible to identify all sources.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
Test your knowledge on the autonomic and somatic nervous systems with this quiz. Explore the roles of different divisions, nerve fibers, and their functions within the human body. Perfect for students studying physiology or related fields.