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Nephrotic Syndrome Hypercoagulability Factors Quiz

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Nephrotic Syndrome Hypercoagulability Factors Quiz

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Questions and Answers

What is the primary cause of hypercoagulability in nephrotic syndrome?

Vascular stasis due to hemoconcentration

Decreased platelet number and aggregability

Increase in hepatic production of fibrinog

Urinary loss of antithrombin III (correct)

Infants with congenital nephrotic syndrome of the Finnish type (CNF) are typically born at which stage?

Full term

Extremely prematurely (28 to 32 weeks)

Prematurely (35 to 38 weeks) (correct)

After gestational age

Which of the following is NOT a common feature in infants with CNF at birth?

Mild proteinuria (correct)

Edema

Flexion deformities of hips, knees, and elbows

Delayed ossification

How does proteinuria progress in infants with CNF?

It becomes less selective over time (D) Signup and view all the answers

What is the main cause of hypoalbuminemia in infants with CNF?

Urinary protein losses (C) Signup and view all the answers

What is a common consequence of nephrotic syndrome in affected infants?

Susceptibility to bacterial infections (B) Signup and view all the answers

What is the typical position of ears in infants with CNF?

Low-set (C) Signup and view all the answers

What is a common characteristic of the kidneys in nephrotic syndrome?

Slightly enlarged and hyperechogenic (A) Signup and view all the answers

What is a common age range for end-stage kidney disease in nephrotic syndrome?

Three to eight years (A) Signup and view all the answers

What is a reported effect of certain NPHS1 variants?

Late onset of end-stage kidney disease (D) Signup and view all the answers

What was a common finding in a case series of Maori children with CNS?

Prolonged kidney survival with medical therapy (A) Signup and view all the answers

What is a medication used in medical therapy for CNS in Maori children?

Indomethacin (A) Signup and view all the answers