12 Questions
What is the primary cause of hypercoagulability in nephrotic syndrome?
Urinary loss of antithrombin III
Infants with congenital nephrotic syndrome of the Finnish type (CNF) are typically born at which stage?
Prematurely (35 to 38 weeks)
Which of the following is NOT a common feature in infants with CNF at birth?
Mild proteinuria
How does proteinuria progress in infants with CNF?
It becomes less selective over time
What is the main cause of hypoalbuminemia in infants with CNF?
Urinary protein losses
What is a common consequence of nephrotic syndrome in affected infants?
Susceptibility to bacterial infections
What is the typical position of ears in infants with CNF?
Low-set
What is a common characteristic of the kidneys in nephrotic syndrome?
Slightly enlarged and hyperechogenic
What is a common age range for end-stage kidney disease in nephrotic syndrome?
Three to eight years
What is a reported effect of certain NPHS1 variants?
Late onset of end-stage kidney disease
What was a common finding in a case series of Maori children with CNS?
Prolonged kidney survival with medical therapy
What is a medication used in medical therapy for CNS in Maori children?
Indomethacin
Test your knowledge on the factors contributing to hypercoagulability in nephrotic syndrome. Learn about the increased platelet number and aggregability, vascular stasis, hepatic production of fibrinogen, urinary loss of antithrombin III, and protein S. Explore complications related to nephrotic syndrome in infants.
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