Nephrotic Syndrome Hypercoagulability Factors Quiz
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Questions and Answers

What is the primary cause of hypercoagulability in nephrotic syndrome?

  • Vascular stasis due to hemoconcentration
  • Decreased platelet number and aggregability
  • Increase in hepatic production of fibrinog
  • Urinary loss of antithrombin III (correct)
  • Infants with congenital nephrotic syndrome of the Finnish type (CNF) are typically born at which stage?

  • Full term
  • Extremely prematurely (28 to 32 weeks)
  • Prematurely (35 to 38 weeks) (correct)
  • After gestational age
  • Which of the following is NOT a common feature in infants with CNF at birth?

  • Mild proteinuria (correct)
  • Edema
  • Flexion deformities of hips, knees, and elbows
  • Delayed ossification
  • How does proteinuria progress in infants with CNF?

    <p>It becomes less selective over time</p> Signup and view all the answers

    What is the main cause of hypoalbuminemia in infants with CNF?

    <p>Urinary protein losses</p> Signup and view all the answers

    What is a common consequence of nephrotic syndrome in affected infants?

    <p>Susceptibility to bacterial infections</p> Signup and view all the answers

    What is the typical position of ears in infants with CNF?

    <p>Low-set</p> Signup and view all the answers

    What is a common characteristic of the kidneys in nephrotic syndrome?

    <p>Slightly enlarged and hyperechogenic</p> Signup and view all the answers

    What is a common age range for end-stage kidney disease in nephrotic syndrome?

    <p>Three to eight years</p> Signup and view all the answers

    What is a reported effect of certain NPHS1 variants?

    <p>Late onset of end-stage kidney disease</p> Signup and view all the answers

    What was a common finding in a case series of Maori children with CNS?

    <p>Prolonged kidney survival with medical therapy</p> Signup and view all the answers

    What is a medication used in medical therapy for CNS in Maori children?

    <p>Indomethacin</p> Signup and view all the answers

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