Minimal Change Disease and Nephrotic Syndrome Quiz

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Questions and Answers

What is the most common pathology associated with the given symptoms?

Minimal Change Disease (MCD)

Which symptom is often observed in cases of Focal Segmental Glomerulosclerosis (FSGS) but not in Minimal Change Disease (MCD)?

Hematuria

What is the typical age of onset for Minimal Change Disease (MCD)?

7-12 years

What is the usual response to steroids in cases of Minimal Change Disease (MCD)?

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Study Notes

Nephrotic Syndrome Pathologies

  • Focal Segmental Glomerulosclerosis (FSGS) and Minimal Change Disease (MCD) are two common pathologies associated with nephrotic syndrome.

Distinguishing Features

  • The presence of hemosiderin in the urine is often observed in FSGS but not in MCD.

Minimal Change Disease (MCD)

  • Typical age of onset is in childhood, with peak incidence between 6-10 years old.
  • MCD is typically steroid-responsive, with rapid remission of proteinuria following steroid treatment.

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