Nephrotic Syndrome Characteristics Quiz
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Questions and Answers

What are the primary components indicating nephrotic syndrome?

  • Bacteriuria, edema, azotemia
  • Proteinuria, hematuria, hypertension
  • Hematuria, azotemia, hypertension
  • Proteinuria, edema, hyperlipidemia (correct)

A 22-year-old girl presents to you after waking with a swollen face. Arterial hypertension, blood pressure is 160/80 mmHg. There is swelling of the face, abdomen, and legs. Serum creatinine is 1.6 mg/dl; (normal range up to 1.0 mg/dl); Albumin is 2.7 g/dl; (normal range 3.5-4.5 g/dl); The 24-hour urine excretion is 2.6g. The most likely diagnostic test should be performed is

  • Kidney biopsy
  • Renal scan with Tc-99
  • MRI
  • CT (correct)

Which of the following classes of antihypertensive medications is not recommended for initial treatment?

  • Thiazide-type diuretics
  • Angiotensin receptor blockers
  • Potassium-sparing diuretics (correct)
  • ACE inhibitor

Which of the following causes of renovascular hypertension is more common among younger patients?

<p>Fibromuscular dysplasia (B)</p> Signup and view all the answers

Which of the following diagnostic tests for renovascular hypertension may also be therapeutic?

<p>Renal angiography (A)</p> Signup and view all the answers

The cause of death of most patients with chronic kidney disease is

<p>Cardiovascular disease (C)</p> Signup and view all the answers

In a patient with GFR 22, the drug of choice for hypertension is?

<p>ACE inhibitors (B)</p> Signup and view all the answers

The nephrotic syndrome is primarily due to:

<p>Increased permeability of the glomerular filtration barrier (A)</p> Signup and view all the answers

Nephrotic syndrome is characterized by:

<p>Proteinuria, edema, hyperlipidemia (D)</p> Signup and view all the answers

Normal range for proteinuria in a 24-hour urine collection is

<p>&lt; 140 (150) (B)</p> Signup and view all the answers

The clinical stage of chronic kidney disease called "renal insufficiency" or stage 3 to 4 disease,

<p>Is associated with a nephron loss of about 20% (B)</p> Signup and view all the answers

A 75-year-old male with hypertension (170/100) has had a renal ultrasound performed: right kidney is shrunken, left - N. What is the primary diagnosis?

<p>Renal artery stenosis (C)</p> Signup and view all the answers

Flashcards

Nephrotic syndrome characteristics

A condition marked by proteinuria, edema, and hyperlipidemia.

Proteinuria in 24-hour urine

The amount of protein in a 24-hour urine sample; a normal range needs information to be stated.

Nephrotic syndrome exclusion

Not characterized by hematuria(blood in urine), azotemia(waste product buildup in the blood ), or hypertension(high blood pressure).

Benign prostate hyperplasia

An often age-related enlargement of the prostate gland.

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Normal range for 24-hour urine protein

A specified range that is crucial to interpret the health of the urinary system.

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Swollen face, abdomen, and legs

A symptom of fluid retention in the body (edema), commonly seen in cases of kidney dysfunction.

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High serum creatinine (1.6 mg/dl)

Indicates kidney damage, as creatinine is a waste product normally filtered by the kidneys.

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Low albumin (2.7 g/dl)

Indicates reduced protein in the blood, often a sign of kidney disease where proteins are lost in urine.

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High 24-hour urine protein (2.6g)

A key characteristic of nephrotic syndrome, indicating significant protein leakage through the damaged kidneys.

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Nephrotic syndrome

A kidney disorder characterized by massive proteinuria, edema, and hyperlipidemia.

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Kidney biopsy

A procedure where a small tissue sample is taken from the kidney to examine under a microscope, aiding in diagnosing kidney diseases.

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Why not potassium-sparing diuretics first?

They are not recommended for initial treatment of hypertension because they can worsen potassium levels in the blood, potentially causing complications.

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Fibromuscular dysplasia

A condition where the arteries in the kidneys develop abnormal growth, leading to narrowing and high blood pressure.

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Renal angiography

A diagnostic test that uses a dye and X-rays to visualize the blood vessels in the kidneys.

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Why is renal angiography therapeutic?

It can diagnose and treat renovascular hypertension by widening narrowed arteries with balloon angioplasty or stents.

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Cardiovascular disease

The leading cause of death in patients with chronic kidney disease.

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GFR (glomerular filtration rate)

Measures how well the kidneys are filtering waste products from the blood.

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ACE inhibitors for low GFR

These medications are often preferred for managing hypertension in patients with low GFR as they help protect the kidneys.

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Increased glomerular filtration barrier permeability

The primary cause of nephrotic syndrome, where the filtering membrane in the kidneys becomes leaky, allowing proteins to escape into the urine.

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Nephrotic syndrome symptoms

Characterized by proteinuria, edema, and hyperlipidemia.

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Study Notes

Nephrotic Syndrome Characteristics

  • Characterized by proteinuria, edema, and hyperlipidemia.

Normal Proteinuria Range

  • (Missing data; the question asks for the normal range, but no range is provided)

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Description

Test your knowledge on the characteristics of nephrotic syndrome, focusing on key features like proteinuria, edema, and hyperlipidemia. This quiz will help reinforce your understanding of nephrology concepts and the clinical implications of these symptoms.

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