Neonatal Anesthesia and Airway Overview
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Questions and Answers

What is the most significant factor for ductal closure in a full-term neonate?

  • Inhalation of amniotic fluid
  • Oxygen levels increased from taking their first breath (correct)
  • Maternal medication during labor
  • Body temperature regulation
  • Which structure closes functionally within the first hour of a newborn's life? select 2

  • Foramen ovale (correct)
  • Ductus arteriosus
  • Ductus venosus (correct)
  • Pulmonary artery
  • What does a score of 7 or higher on the APGAR scale indicate?

  • Normal condition of the newborn (correct)
  • Poor cardiovascular function
  • Immediate intervention required
  • Severe respiratory distress
  • What technique regarding meconium aspiration is no longer recommended for newborns?

    <p>Routine suctioning</p> Signup and view all the answers

    What does functional closure of the fetal openings indicate in newborns?

    <p>The openings are essentially closed but may slightly remain open.</p> Signup and view all the answers

    What physiological change may occur if there is inadequate ductal closure after birth?

    <p>Persistent pulmonary hypertension leading to rapid desaturation.</p> Signup and view all the answers

    Which characteristic of the neonatal airway poses challenges to ventilation?

    <p>The airway has a more anterior and funnel-shaped structure.</p> Signup and view all the answers

    What is the main indicator of a potential shunt in a neonate?

    <p>Difference in SPO2 levels between hand and foot (preductally).</p> Signup and view all the answers

    What physiological condition is identified as the most common cause of neonatal depression?

    <p>Intrauterine asphyxia.</p> Signup and view all the answers

    What are the three fetal shunts? (Select all that apply)

    <p>Ductus arteriosus - PA to aorta</p> Signup and view all the answers

    What is anatomical closure in relation to shunts?

    <p>It refers to shunts being fully closed typically within the first year of life.</p> Signup and view all the answers

    What causes persistent pulmonary hypertension in the neonate? (Select all that apply)

    <p>Patent ductus arteriosus (PDA)</p> Signup and view all the answers

    What is the response to hypercapnia in neonates with pulmonary hypertension?

    <p>Decreased responsiveness</p> Signup and view all the answers

    Parasympathetic NS is more developed than the sympathetic nervous system in the neonate

    <p>True</p> Signup and view all the answers

    What is the benefit of the parasympathetic nervous system (PSNS) being more developed than the sympathetic nervous system (SNS) in neonates? select 3

    <p>Facilitation of rest and digestion</p> Signup and view all the answers

    What should be used to intubate a micropremie?

    <p>Miller 00 and 2.5 uncuffed ETT</p> Signup and view all the answers

    What should be used to intubate a newborn?

    <p>Miller 0 blade and uncuffed 3-3.5 ETT</p> Signup and view all the answers

    When should ventilatory support be given to a neonate?

    <p>Both A and C</p> Signup and view all the answers

    When should CPR be started in a neonate?

    <p>HR &lt; 60 bpm</p> Signup and view all the answers

    What is the dosage of atropine in pediatrics? select 2

    <p>IV 10 mcg/kg</p> Signup and view all the answers

    What medication can cause neurodegenerative changes in pediatric patients?

    <p>Ketamine</p> Signup and view all the answers

    What drug is a mainstay for sedation and analgesia in pediatric patients?

    <p>Fentanyl</p> Signup and view all the answers

    Which medication is not FDA approved for pediatric patients and has less clearance in neonates?

    <p>Dexmedetomidine</p> Signup and view all the answers

    Which neuromuscular blocking drug (NMBD) requires increased doses because of those listed below, it has the largest volume of distribution (Vd) due to its water solubility?

    <p>Succinylcholine</p> Signup and view all the answers

    Which medication requires serial EKGs due to its association with prolonged QT interval?

    <p>Methadone</p> Signup and view all the answers

    The second dose of ______ is associated with bradycardia and sinus arrest.

    <p>Succinylcholine</p> Signup and view all the answers

    Which neuromuscular blocking drug (NMBD) is characterized by hepatic metabolism with active metabolites, requiring decreased doses in neonates?

    <p>Vecuronium</p> Signup and view all the answers

    Sugammadex is not approved for use in pediatric patients

    <p>True</p> Signup and view all the answers

    What reversal agents are used to reverse the effects of neuromuscular blocking drugs (NMBDs) in pediatrics?

    <p>Neostigmine with glycopyrrolate</p> Signup and view all the answers

    What is involved in the transition to newborn circulation after birth? (Select all that apply)

    <p>Closure of the ductus arteriosus allowing all the blood leaving the RV to travel to the lungs via the PA</p> Signup and view all the answers

    At what gestational age is the neonate's pulmonary system mature enough for gas exchange?

    <p>24-26 weeks</p> Signup and view all the answers

    The neonate's neuromuscular junction (NMJ) is more sensitive to the effects of ______

    <p>non-depolarizing neuromuscular blockers due to increased loading doses and immaturity of muscle fibers</p> Signup and view all the answers

    What is an expected finding in the complete blood count (CBC) of a neonate?

    <p>Hgb levels are higher due to fetal hemoglobin</p> Signup and view all the answers

    Neonates do not respond well to inotropes due to their poorly developed SNS

    <p>True</p> Signup and view all the answers

    What does preductal SpO2 measure?

    <p>Oxygen saturation in the blood before it passes to the ductus arteriosus</p> Signup and view all the answers

    When does functional closure of the ductus arteriosus occur?

    <p>10-96 hours after birth</p> Signup and view all the answers

    When does functional closure of the foramen ovale and ductus venosus occur?

    <p>Within several minutes after birth</p> Signup and view all the answers

    Study Notes

    Neonatal Anesthesia

    • Transition to Newborn Circulation: Critical 72-hour period after birth.

      • Immediate first breath triggers closure of 3 fetal openings:
        • Ductus arteriosus
        • Ductus venosus
        • Foramen ovale (closes within the first hour).
      • Functional closure differs from anatomic closure:
        • Functional closure is largely closed, but not completely.
        • Anatomic closure is fully closed (occurs within the first year for most).
    • APGAR Score: A measure of newborn health.

      • A score of 7 or greater is considered normal.
      • Scored at 1 and 5 minutes after birth.
    • Persistent Pulmonary Hypertension (PPHN): A complication where shunts (PDA and PFO) do not close immediately.

      • Characterized by rapid desaturation and decreased responsiveness to increased carbon dioxide.

    Neonatal Airway

    • Structure: Airway is more anterior and funnel-shaped than in adults.
      • Larger tongue and occiput (back of head) are present.
      • Cricoid cartilage is the narrowest part of the pediatric airway.

    Meconium Aspiration

    • Cause: A stressed fetus may pass meconium (first stool) into the amniotic fluid.
      • This can occur in utero or at birth.
    • Complications: Meconium can obstruct the airway (tracheobronchial system), requiring respiratory support.
    • Current Practice: Routine suctioning of newborns is no longer recommended.

    Neonatal Cardiovascular System

    • Oxygen's Role: In full-term newborns, oxygen levels are key for ductal closure.
    • Nervous System: Parasympathetic nervous system (PSNS) is more developed than the sympathetic nervous system (SNS)
    • Monitoring: Pulse oximetry (SPO2) should be measured pre-ductally (in right hand) and compared to the foot.
      • Differences indicate a shunt.
    • Common Cause of Depression: Intrauterine asphyxia (lack of oxygen).
    • Interventions: Ventilation support may be required based on Heart Rate.

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    Description

    This quiz covers critical aspects of neonatal anesthesia, including the transition to newborn circulation, APGAR scoring, and persistent pulmonary hypertension. Additionally, it explores the structure of the neonatal airway, focusing on its unique characteristics compared to adults. Test your understanding of these vital concepts in neonatal care.

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