Podcast
Questions and Answers
What is the purpose of the enzymes released by the sperm during fertilization?
What is the purpose of the enzymes released by the sperm during fertilization?
What is the approximate duration of sperm viability inside the female reproductive tract?
What is the approximate duration of sperm viability inside the female reproductive tract?
What is the location where fertilization of a human egg usually takes place?
What is the location where fertilization of a human egg usually takes place?
What is the purpose of the corona radiata during fertilization?
What is the purpose of the corona radiata during fertilization?
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What is the approximate number of sperm that reach the uterine tube out of those deposited in the vagina?
What is the approximate number of sperm that reach the uterine tube out of those deposited in the vagina?
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What is the result of the union of sperm and egg during fertilization?
What is the result of the union of sperm and egg during fertilization?
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What is the duration of time during which an unfertilized egg remains viable?
What is the duration of time during which an unfertilized egg remains viable?
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What is the percentage of sperm that encounter the egg in the uterine tube?
What is the percentage of sperm that encounter the egg in the uterine tube?
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What occurs if a person consumes excess water faster than their kidneys can excrete it?
What occurs if a person consumes excess water faster than their kidneys can excrete it?
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What is the function of the glomerulus?
What is the function of the glomerulus?
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What is the result of severe dehydration?
What is the result of severe dehydration?
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How many times does the entire blood volume pass through the kidneys daily?
How many times does the entire blood volume pass through the kidneys daily?
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What is the term for the process of maintaining blood osmolarity within strict limits?
What is the term for the process of maintaining blood osmolarity within strict limits?
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What is the function of the renal tubule?
What is the function of the renal tubule?
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What is the term for the microscopic urine-forming units in the kidneys?
What is the term for the microscopic urine-forming units in the kidneys?
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What occurs if the kidneys cannot conserve enough water?
What occurs if the kidneys cannot conserve enough water?
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What is the primary function of the antibodies that are selectively transported across the placenta?
What is the primary function of the antibodies that are selectively transported across the placenta?
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What is the primary mechanism by which the placenta allows exchange of substances between the fetus and mother?
What is the primary mechanism by which the placenta allows exchange of substances between the fetus and mother?
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What is the main function of the urinary system in most animals?
What is the main function of the urinary system in most animals?
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What is the term for the elimination of any form of waste from the body?
What is the term for the elimination of any form of waste from the body?
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What are the primary nitrogenous wastes excreted by the urinary system?
What are the primary nitrogenous wastes excreted by the urinary system?
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What is the composition of urine?
What is the composition of urine?
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What is the purpose of the umbilical arteries and veins?
What is the purpose of the umbilical arteries and veins?
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What organs make up the mammalian urinary system?
What organs make up the mammalian urinary system?
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What is the primary function of the distal tubule in the nephron?
What is the primary function of the distal tubule in the nephron?
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Which segment of the nephron is primarily responsible for secretion of substances into the renal tubule?
Which segment of the nephron is primarily responsible for secretion of substances into the renal tubule?
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What is the main difference between reabsorption in the proximal tubule and distal tubule?
What is the main difference between reabsorption in the proximal tubule and distal tubule?
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What is the composition of the filtrate when it enters the distal tubule?
What is the composition of the filtrate when it enters the distal tubule?
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What determines the concentration of urine produced in the distal tubule and collecting duct?
What determines the concentration of urine produced in the distal tubule and collecting duct?
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What is the primary function of the nephron loop?
What is the primary function of the nephron loop?
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Which of the following substances is NOT secreted into the renal tubule?
Which of the following substances is NOT secreted into the renal tubule?
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What is the main function of hormones in the distal tubule and collecting duct?
What is the main function of hormones in the distal tubule and collecting duct?
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What is the primary function of the glomerular filtration process in the nephron?
What is the primary function of the glomerular filtration process in the nephron?
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What percentage of the blood's fluid is forced out through the glomerular capillary walls during filtration?
What percentage of the blood's fluid is forced out through the glomerular capillary walls during filtration?
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What type of substances remain in the blood after glomerular filtration?
What type of substances remain in the blood after glomerular filtration?
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What is the primary function of the peritubular capillaries in the nephron?
What is the primary function of the peritubular capillaries in the nephron?
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What is the role of the bicarbonate ion (HCO3-) in the body?
What is the role of the bicarbonate ion (HCO3-) in the body?
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What percentage of the solutes in the glomerular filtrate is made up of urea?
What percentage of the solutes in the glomerular filtrate is made up of urea?
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What is the primary function of reabsorption in the nephron?
What is the primary function of reabsorption in the nephron?
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What is the function of the glomerular capsule in the nephron?
What is the function of the glomerular capsule in the nephron?
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Fertilization usually takes place in the uterus.
Fertilization usually takes place in the uterus.
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The corona radiata is a barrier that facilitates fertilization.
The corona radiata is a barrier that facilitates fertilization.
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All sperm deposited in the vagina reach the uterine tube.
All sperm deposited in the vagina reach the uterine tube.
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The enzymes released by the sperm strengthen the barriers around the egg.
The enzymes released by the sperm strengthen the barriers around the egg.
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Fertilization results in a haploid zygote.
Fertilization results in a haploid zygote.
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The jelly-like zona pellucida is the outermost layer of the egg.
The jelly-like zona pellucida is the outermost layer of the egg.
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Only one sperm reaches the egg during fertilization.
Only one sperm reaches the egg during fertilization.
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Cell differentiation, gastrulation, and organogenesis occur during the last two months of pregnancy.
Cell differentiation, gastrulation, and organogenesis occur during the last two months of pregnancy.
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The zygote undergoes multiple cleavage divisions in the uterus, becoming a morula on its way to the uterine tube.
The zygote undergoes multiple cleavage divisions in the uterus, becoming a morula on its way to the uterine tube.
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By about the seventh day after fertilization, the zygote has developed into a hollow ball of cells, known as a blastocyst.
By about the seventh day after fertilization, the zygote has developed into a hollow ball of cells, known as a blastocyst.
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The inner cell mass of the blastocyst will become the chorion.
The inner cell mass of the blastocyst will become the chorion.
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Gastrulation occurs during the first week of development.
Gastrulation occurs during the first week of development.
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The embryonic disk consists of three layers of cells.
The embryonic disk consists of three layers of cells.
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The slit in the amnion side of the embryonic disk is equivalent to the blastopore in amphibians.
The slit in the amnion side of the embryonic disk is equivalent to the blastopore in amphibians.
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The cells exposed to the blastocyst fluid produce the embryo proper.
The cells exposed to the blastocyst fluid produce the embryo proper.
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All the cells of the inner cell mass have the potential to develop into only specific types of tissue in the human body.
All the cells of the inner cell mass have the potential to develop into only specific types of tissue in the human body.
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The cells remaining on the surface become endoderm
The cells remaining on the surface become endoderm
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Organogenesis begins during the first two weeks of development
Organogenesis begins during the first two weeks of development
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The heart starts to beat around the end of the fifth week
The heart starts to beat around the end of the fifth week
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The umbilical cord forms from the fusion of the yolk stalk and the amnion
The umbilical cord forms from the fusion of the yolk stalk and the amnion
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The chorion grows finger-like villi that extend into the yolk sac
The chorion grows finger-like villi that extend into the yolk sac
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The embryo's blood and the mother's blood mix directly in the chorionic villi
The embryo's blood and the mother's blood mix directly in the chorionic villi
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Oxygen and nutrients diffuse from the embryo to the mother
Oxygen and nutrients diffuse from the embryo to the mother
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Carbon dioxide and other wastes diffuse from the mother to the embryo
Carbon dioxide and other wastes diffuse from the mother to the embryo
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The collecting duct carries urine through decreasingly concentrated interstitial fluid within the renal medulla.
The collecting duct carries urine through decreasingly concentrated interstitial fluid within the renal medulla.
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The interstitial fluid within the renal medulla contains low concentrations of salt and urea.
The interstitial fluid within the renal medulla contains low concentrations of salt and urea.
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When the collecting duct is impermeable to water, the difference in osmolarity between the urine and the interstitial fluid causes water to leave the urine and enter the interstitial fluid by osmosis.
When the collecting duct is impermeable to water, the difference in osmolarity between the urine and the interstitial fluid causes water to leave the urine and enter the interstitial fluid by osmosis.
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The key to producing concentrated urine lies in the decreased solute concentration of the surrounding fluid.
The key to producing concentrated urine lies in the decreased solute concentration of the surrounding fluid.
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The distal tubule and collecting duct will become less permeable to water in order to conserve water.
The distal tubule and collecting duct will become less permeable to water in order to conserve water.
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Returning water to the blood is a minor function of the collecting duct.
Returning water to the blood is a minor function of the collecting duct.
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The concentration of dissolved substances in the filtrate is indicated by the intensity of the red color.
The concentration of dissolved substances in the filtrate is indicated by the intensity of the red color.
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The nephron loop is responsible for reabsorption of substances into the renal tubule.
The nephron loop is responsible for reabsorption of substances into the renal tubule.
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If the kidneys cannot conserve enough water, blood osmolarity increases and blood volume decreases.
If the kidneys cannot conserve enough water, blood osmolarity increases and blood volume decreases.
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The renal corpuscle is responsible for conducting the filtrate as it is converted to urine.
The renal corpuscle is responsible for conducting the filtrate as it is converted to urine.
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The glomerulus is a knot of impermeable capillaries that allow only small molecules to ooze out.
The glomerulus is a knot of impermeable capillaries that allow only small molecules to ooze out.
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Each kidney contains roughly 2 million microscopic urine-forming units called nephrons.
Each kidney contains roughly 2 million microscopic urine-forming units called nephrons.
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The entire blood volume passes through the kidneys about 30 times daily.
The entire blood volume passes through the kidneys about 30 times daily.
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The renal tubule is responsible for pressure-filtering the blood and collecting the resulting fluid.
The renal tubule is responsible for pressure-filtering the blood and collecting the resulting fluid.
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Nephrons are packed together in the renal medulla, with a thin extension of each nephron extending into the renal cortex.
Nephrons are packed together in the renal medulla, with a thin extension of each nephron extending into the renal cortex.
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Swelling in brain cells causes high blood pressure, dizziness, and confusion.
Swelling in brain cells causes high blood pressure, dizziness, and confusion.
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What is the primary function of the nephron loop in the renal tubule?
What is the primary function of the nephron loop in the renal tubule?
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What is the sequence of blood vessels that support the nephron's role in filtering the blood?
What is the sequence of blood vessels that support the nephron's role in filtering the blood?
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What are the three processes involved in urine formation in the nephrons of the kidneys?
What are the three processes involved in urine formation in the nephrons of the kidneys?
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What is the main function of the distal tubule in the nephron?
What is the main function of the distal tubule in the nephron?
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What is the purpose of the peritubular capillaries surrounding the renal tubule?
What is the purpose of the peritubular capillaries surrounding the renal tubule?
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What is the function of the glomerulus in the nephron?
What is the function of the glomerulus in the nephron?
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What is the term for the microscopic urine-forming units in the kidneys?
What is the term for the microscopic urine-forming units in the kidneys?
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What is the primary function of the collecting ducts in the kidney?
What is the primary function of the collecting ducts in the kidney?
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What two factors facilitate glomerular filtration in the nephron?
What two factors facilitate glomerular filtration in the nephron?
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What percentage of the blood's fluid is forced out through the glomerular capillary walls during filtration?
What percentage of the blood's fluid is forced out through the glomerular capillary walls during filtration?
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What is the primary function of reabsorption in the nephron?
What is the primary function of reabsorption in the nephron?
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What is the role of the bicarbonate ion (HCO3-) in the body?
What is the role of the bicarbonate ion (HCO3-) in the body?
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What percentage of the solutes in the glomerular filtrate is made up of urea?
What percentage of the solutes in the glomerular filtrate is made up of urea?
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What is the function of the peritubular capillaries in the nephron?
What is the function of the peritubular capillaries in the nephron?
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What is the function of the glomerular capsule in the nephron?
What is the function of the glomerular capsule in the nephron?
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How do substances move from the renal tubules back into the bloodstream during reabsorption?
How do substances move from the renal tubules back into the bloodstream during reabsorption?
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What is the primary consequence of excessive water consumption, leading to osmosis into the interstitial fluid and then into cells?
What is the primary consequence of excessive water consumption, leading to osmosis into the interstitial fluid and then into cells?
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Describe the structure and function of the glomerulus in the nephron.
Describe the structure and function of the glomerulus in the nephron.
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What is the consequence of severe dehydration, if the kidneys cannot conserve enough water?
What is the consequence of severe dehydration, if the kidneys cannot conserve enough water?
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What is the primary function of the renal tubule in the nephron?
What is the primary function of the renal tubule in the nephron?
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What is the significance of the entire blood volume passing through the kidneys about 60 times daily?
What is the significance of the entire blood volume passing through the kidneys about 60 times daily?
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Describe the role of the glomerular capsule in the nephron.
Describe the role of the glomerular capsule in the nephron.
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What is the consequence of the kidneys' inability to conserve enough water in cases of dehydration?
What is the consequence of the kidneys' inability to conserve enough water in cases of dehydration?
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What is the significance of the renal corpuscle in the nephron?
What is the significance of the renal corpuscle in the nephron?
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What is the primary function of the distal tubule in terms of reabsorption?
What is the primary function of the distal tubule in terms of reabsorption?
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What is the primary function of secretion in the nephron?
What is the primary function of secretion in the nephron?
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What determines the concentration of urine produced in the distal tubule and collecting duct?
What determines the concentration of urine produced in the distal tubule and collecting duct?
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What is the primary function of the nephron loop in terms of reabsorption?
What is the primary function of the nephron loop in terms of reabsorption?
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What is the primary difference between reabsorption in the proximal tubule and distal tubule?
What is the primary difference between reabsorption in the proximal tubule and distal tubule?
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What is the composition of the filtrate when it enters the distal tubule?
What is the composition of the filtrate when it enters the distal tubule?
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What is the primary function of hormones in the distal tubule and collecting duct?
What is the primary function of hormones in the distal tubule and collecting duct?
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What is the primary function of the renal tubule in terms of secretion?
What is the primary function of the renal tubule in terms of secretion?
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What role do certain types of antibodies play in defending the newborn infant against disease, and how are they transported to the embryo?
What role do certain types of antibodies play in defending the newborn infant against disease, and how are they transported to the embryo?
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What are the two major roles that urinary systems play in most animals, and what substances do they excrete?
What are the two major roles that urinary systems play in most animals, and what substances do they excrete?
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How does the placenta allow for the exchange of substances between the fetus and mother, while keeping their blood supplies separate?
How does the placenta allow for the exchange of substances between the fetus and mother, while keeping their blood supplies separate?
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What is the term for the process of eliminating any form of waste from the body, and what are the primary nitrogenous wastes excreted by the urinary system?
What is the term for the process of eliminating any form of waste from the body, and what are the primary nitrogenous wastes excreted by the urinary system?
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What are the components of the mammalian urinary system, and what is the function of the urinary system in most animals?
What are the components of the mammalian urinary system, and what is the function of the urinary system in most animals?
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What is the composition of urine, and what is its role in the body?
What is the composition of urine, and what is its role in the body?
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What are the umbilical arteries and veins responsible for, and how do they contribute to the development of the fetus?
What are the umbilical arteries and veins responsible for, and how do they contribute to the development of the fetus?
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Why is the placenta not a complete barrier to the transfer of substances between the mother and fetus, and what are the implications of this?
Why is the placenta not a complete barrier to the transfer of substances between the mother and fetus, and what are the implications of this?
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Fertilization, the union of sperm and egg, produces a ______ zygote.
Fertilization, the union of sperm and egg, produces a ______ zygote.
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Men produce sperm more or less ______, and women ovulate about once a month.
Men produce sperm more or less ______, and women ovulate about once a month.
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Sperm, under ideal conditions, may live for 2 to (rarely) ______ days inside the female reproductive tract.
Sperm, under ideal conditions, may live for 2 to (rarely) ______ days inside the female reproductive tract.
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The egg is surrounded by ______ follicle cells when it leaves the ovary.
The egg is surrounded by ______ follicle cells when it leaves the ovary.
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The ______ pellucida lies between the corona radiata and the egg.
The ______ pellucida lies between the corona radiata and the egg.
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Perhaps 1 in ______ of the sperm deposited in the vagina reaches the uterine tube.
Perhaps 1 in ______ of the sperm deposited in the vagina reaches the uterine tube.
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Cell differentiation, gastrulation, and organogenesis occur during the first two ______.
Cell differentiation, gastrulation, and organogenesis occur during the first two ______.
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Fertilization of a human egg usually takes place in the ______ tube.
Fertilization of a human egg usually takes place in the ______ tube.
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The outermost layer of each kidney is the ______ cortex.
The outermost layer of each kidney is the ______ cortex.
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The ______ medulla surrounds a branched, funnel-like chamber called the renal pelvis.
The ______ medulla surrounds a branched, funnel-like chamber called the renal pelvis.
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The average adult ______ can hold about a pint (500 milliliters) of urine.
The average adult ______ can hold about a pint (500 milliliters) of urine.
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Urine is retained in the bladder by two circular ______ muscles.
Urine is retained in the bladder by two circular ______ muscles.
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An important function of the kidney is ______ regulation.
An important function of the kidney is ______ regulation.
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The ureter is a narrow, muscular tube that contracts rhythmically to propel the urine from the kidney to the ______.
The ureter is a narrow, muscular tube that contracts rhythmically to propel the urine from the kidney to the ______.
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Urine exits the body through the ______, a single narrow tube.
Urine exits the body through the ______, a single narrow tube.
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Water balance is essential for ______.
Water balance is essential for ______.
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The renal tubule consists of three parts: The first portion is the _______________ tubule.
The renal tubule consists of three parts: The first portion is the _______________ tubule.
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The filtrate then enters the second portion of the tubule, the nephron loop (also called the _______________ of Henle).
The filtrate then enters the second portion of the tubule, the nephron loop (also called the _______________ of Henle).
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The main function of the nephron loop is to produce and maintain a high concentration of _______________ ions (Na+ and Cl-) in the interstitial fluid of the renal medulla.
The main function of the nephron loop is to produce and maintain a high concentration of _______________ ions (Na+ and Cl-) in the interstitial fluid of the renal medulla.
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The filtrate is finally converted into _______________ in the distal tubule.
The filtrate is finally converted into _______________ in the distal tubule.
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Urine is produced in the nephrons of the kidneys by three processes: _______________, Reabsorption, and Secretion.
Urine is produced in the nephrons of the kidneys by three processes: _______________, Reabsorption, and Secretion.
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Blood is carried to the kidney by the _______________ artery.
Blood is carried to the kidney by the _______________ artery.
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Collecting ducts conduct urine from the renal cortex, through the renal medulla, and into the _______________ pelvis.
Collecting ducts conduct urine from the renal cortex, through the renal medulla, and into the _______________ pelvis.
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The peritubular capillaries conduct the blood into a _______________ that joins the renal vein.
The peritubular capillaries conduct the blood into a _______________ that joins the renal vein.
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When the collecting duct is ______ permeable, water will leave the urine and enter the interstitial fluid by osmosis.
When the collecting duct is ______ permeable, water will leave the urine and enter the interstitial fluid by osmosis.
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The ______ fluid within the renal medulla contains high concentrations of salt and urea.
The ______ fluid within the renal medulla contains high concentrations of salt and urea.
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Returning water to the blood to avoid ______ is a major function of the collecting duct.
Returning water to the blood to avoid ______ is a major function of the collecting duct.
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The key to producing concentrated urine lies in the elevated ______ concentration of the surrounding fluid.
The key to producing concentrated urine lies in the elevated ______ concentration of the surrounding fluid.
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The distal tubule and collecting duct will become more ______ to water, which will leave the urine by osmosis.
The distal tubule and collecting duct will become more ______ to water, which will leave the urine by osmosis.
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The collecting duct carries urine through increasingly concentrated ______ fluid within the renal medulla.
The collecting duct carries urine through increasingly concentrated ______ fluid within the renal medulla.
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Salt enters the ______ fluid from the nephron loop.
Salt enters the ______ fluid from the nephron loop.
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The concentration of dissolved substances in the filtrate is indicated by the intensity of ______ color.
The concentration of dissolved substances in the filtrate is indicated by the intensity of ______ color.
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Most reabsorption takes place in the ______ tubule.
Most reabsorption takes place in the ______ tubule.
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In the ______ tubule, reabsorption is generally under hormonal control.
In the ______ tubule, reabsorption is generally under hormonal control.
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The ______ tubule fine-tunes blood composition by regulating the reabsorption of water and ions.
The ______ tubule fine-tunes blood composition by regulating the reabsorption of water and ions.
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The fluid that has travelled through the nephron becomes ______ as it leaves the distal tubule.
The fluid that has travelled through the nephron becomes ______ as it leaves the distal tubule.
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Secretion occurs primarily in the ______ tubule, but some also occurs in the distal tubule.
Secretion occurs primarily in the ______ tubule, but some also occurs in the distal tubule.
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When the filtrate enters the ______ tubule, about 80% of its water has already been reabsorbed.
When the filtrate enters the ______ tubule, about 80% of its water has already been reabsorbed.
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Concentration of urine occurs in the ______ tubule and collecting duct.
Concentration of urine occurs in the ______ tubule and collecting duct.
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If fluid intake has been low, ______ urine will be produced.
If fluid intake has been low, ______ urine will be produced.
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What is the primary function of the antibodies that are selectively transported across the placenta?
What is the primary function of the antibodies that are selectively transported across the placenta?
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The placenta provides complete protection against disease-causing organisms and harmful chemicals.
The placenta provides complete protection against disease-causing organisms and harmful chemicals.
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What is the primary role of the urinary system in most animals?
What is the primary role of the urinary system in most animals?
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The urinary system excretes cellular wastes, primarily the nitrogenous wastes _______________, urea, and uric acid.
The urinary system excretes cellular wastes, primarily the nitrogenous wastes _______________, urea, and uric acid.
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Match the following components of the mammalian urinary system with their descriptions:
Match the following components of the mammalian urinary system with their descriptions:
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The umbilical arteries carry oxygenated blood from the placenta to the fetus.
The umbilical arteries carry oxygenated blood from the placenta to the fetus.
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What is the term for the elimination of any form of waste from the body?
What is the term for the elimination of any form of waste from the body?
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The placenta allows exchange of _______________ and nutrients between fetal capillaries and maternal blood pools.
The placenta allows exchange of _______________ and nutrients between fetal capillaries and maternal blood pools.
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What happens if a person consumes excess water faster than their kidneys can excrete it?
What happens if a person consumes excess water faster than their kidneys can excrete it?
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The kidneys can filter blood without any problems even if a person is severely dehydrated.
The kidneys can filter blood without any problems even if a person is severely dehydrated.
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What is the function of the renal corpuscle?
What is the function of the renal corpuscle?
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The entire blood volume passes through the kidneys approximately _______________ times daily.
The entire blood volume passes through the kidneys approximately _______________ times daily.
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Match the following parts of the nephron with their functions:
Match the following parts of the nephron with their functions:
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The kidneys can only filter blood, but not produce urine.
The kidneys can only filter blood, but not produce urine.
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What is the result of severe dehydration on brain cells?
What is the result of severe dehydration on brain cells?
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What is the term for the process of maintaining blood osmolarity within strict limits?
What is the term for the process of maintaining blood osmolarity within strict limits?
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What is the primary function of the glomerular filtration process in the nephron?
What is the primary function of the glomerular filtration process in the nephron?
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Blood cells and plasma proteins can pass through the glomerular capillary walls during filtration.
Blood cells and plasma proteins can pass through the glomerular capillary walls during filtration.
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What percentage of the blood's fluid is forced out through the glomerular capillary walls during filtration?
What percentage of the blood's fluid is forced out through the glomerular capillary walls during filtration?
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The bicarbonate ion (HCO3-) is crucial for maintaining a constant ______________________ required for metabolic reactions.
The bicarbonate ion (HCO3-) is crucial for maintaining a constant ______________________ required for metabolic reactions.
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Match the following substances with their functions in the body:
Match the following substances with their functions in the body:
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What is the primary function of reabsorption in the nephron?
What is the primary function of reabsorption in the nephron?
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Urea makes up about 60% of the solutes in the glomerular filtrate.
Urea makes up about 60% of the solutes in the glomerular filtrate.
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What is the primary function of the peritubular capillaries in the nephron?
What is the primary function of the peritubular capillaries in the nephron?
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What is the primary function of the nephron loop?
What is the primary function of the nephron loop?
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The distal tubule is the first part of the renal tubule.
The distal tubule is the first part of the renal tubule.
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What is the main function of the renal tubule?
What is the main function of the renal tubule?
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The collecting ducts conduct urine from the renal cortex, through the renal medulla, and into the ______________.
The collecting ducts conduct urine from the renal cortex, through the renal medulla, and into the ______________.
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What is the term for the process of producing urine in the nephrons?
What is the term for the process of producing urine in the nephrons?
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Match the following parts of the renal tubule with their functions:
Match the following parts of the renal tubule with their functions:
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The renal artery supplies blood to the entire kidney.
The renal artery supplies blood to the entire kidney.
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What is the function of the peritubular capillaries in the nephron?
What is the function of the peritubular capillaries in the nephron?
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What is the main function of the collecting duct in the nephron?
What is the main function of the collecting duct in the nephron?
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The interstitial fluid within the renal medulla has low concentrations of salt and urea.
The interstitial fluid within the renal medulla has low concentrations of salt and urea.
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What is the result of the difference in osmolarity between the urine and the interstitial fluid in the collecting duct?
What is the result of the difference in osmolarity between the urine and the interstitial fluid in the collecting duct?
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The key to producing concentrated urine lies in the elevated solute concentration of the surrounding ________________.
The key to producing concentrated urine lies in the elevated solute concentration of the surrounding ________________.
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What is the primary function of the nephron loop?
What is the primary function of the nephron loop?
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Match the following structures with their functions:
Match the following structures with their functions:
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The proximal tubule is primarily responsible for secretion of substances into the renal tubule.
The proximal tubule is primarily responsible for secretion of substances into the renal tubule.
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What is the result of the collecting duct being water permeable?
What is the result of the collecting duct being water permeable?
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Study Notes
Fertilization, Implantation, and Role of Placenta
- Fertilization: union of sperm and egg, produces a diploid zygote
- Sperm and egg nuclei unite during fertilization
- Process of fertilization:
- Sperm released into vagina during intercourse
- Sperm move through cervix, into uterus, and enter uterine tubes
- Sperm may live for 2-4 days inside female reproductive tract, egg remains viable for a day or so
- Copulation within a day or two of ovulation allows sperm to meet egg in uterine tube
- Barriers to fertilization:
- Corona radiata (accessory follicle cells) surrounds egg
- Zona pellucida (jelly-like) lies between corona radiata and egg
- Fertilization process:
- Hundreds of sperm surround corona radiata, release enzymes to weaken barriers
- Sperm wriggle through to egg, only a few hundred join in attacking barriers
- Importance of fertilization:
- Fertilization usually takes place in uterine tube
- Certain antibodies are selectively transported across placenta from mother to embryo, defending newborn against disease
Role of Placenta
- Placenta:
- Isolates fetus from many assaults, but does not provide complete protection
- Allows exchange of wastes and nutrients between fetal capillaries and maternal blood pools, keeping fetal and maternal blood supplies separate
- Umbilical arteries carry deoxygenated blood from fetus to placenta, umbilical vein carries oxygenated blood back to fetus
Human Excretory System
Urinary System
- Urinary systems: produce and eliminate urine
- Urine composition:
- Waste products from proteins, ions, and excess water-soluble nutrients
- Contains cellular wastes, primarily nitrogenous wastes (ammonia, urea, uric acid)
- Urinary systems' roles:
- Excrete cellular wastes
- Help maintain homeostasis
Mammalian Urinary System
- Consists of paired kidneys, ureters, bladder, and urethra
- Osmoregulation: maintaining blood osmolarity within strict limits
Nephron and its Blood Supply
- Nephrons in kidneys: filter blood, produce urine
- Nephron structure:
- Renal corpuscle and renal tubule
- Renal corpuscle: glomerulus and glomerular capsule
- Nephron function:
- Filtration: removes small molecules and ions from blood
- Reabsorption: returns important substances to blood
- Secretion: actively transports substances into renal tubule for excretion
- Concentration of urine: occurs in distal tubule and collecting duct
Filtration
- Filtration: first step in urine formation, removes small molecules and ions from blood
- Factors facilitating glomerular filtration:
- Porous glomerular capillaries
- High pressure within glomerular capillaries due to narrow arterioles
- Filtration process:
- Fluid forced out of glomerular capillaries into surrounding glomerular capsule
- Blood cells and plasma proteins too large to penetrate capillary walls, remain in blood
Reabsorption
- Reabsorption: returns important substances to blood
- Substances reabsorbed:
- Water, ions (Na+, Cl-, K+, Ca2+, HCO3-), and organic nutrients (vitamins, glucose, amino acids)
- Reabsorption process:
- Molecules move by diffusion or active transport through renal tubule walls into peritubular capillaries
- Most reabsorption occurs in proximal tubule, but also occurs in nephron loop and distal tubule
Secretion
- Secretion: actively transports substances into renal tubule for excretion
- Substances secreted:
- Excess K+, H+, small quantities of ammonia, medicinal and recreational drugs or breakdown products, food additives, and pesticides
- Secretion process:
- Occurs primarily in proximal tubule, but also in distal tubule
- Regulated by circulating hormones to maintain homeostasis
Concentration of Urine
- Concentration of urine: occurs in distal tubule and collecting duct
- Process:
- Filtrate enters distal tubule, about 80% of water has been reabsorbed in proximal tubule and nephron loop
- Additional reabsorption of water precisely regulated to maintain blood osmolarity within narrow limits
- Fluid intake affects concentration of urine produced
Fertilization
- Fertilization is the union of sperm and egg, producing a diploid zygote.
- Sperm and egg nuclei unite during fertilization, with the sperm releasing enzymes to weaken the corona radiata and zona pellucida, allowing the sperm to reach the egg.
- Only a few hundred sperm out of the millions deposited in the vagina reach the uterine tube, and only one sperm fertilizes the egg.
Implantation
- Fertilization usually takes place in the uterine tube, and the resulting zygote undergoes cleavage divisions, becoming a morula on its way to the uterus.
- By around the fifth day after fertilization, the zygote develops into a hollow ball of cells called a blastocyst.
- The outer cell layer of the blastocyst attaches to and then burrows into the lining of the uterus, a process called implantation, forming the placenta.
Cell Differentiation, Gastrulation, and Organogenesis
- During the first two months, cell differentiation, gastrulation, and organogenesis occur.
- Gastrulation begins near the end of the second week, with cells migrating in through a slit in the embryonic disk to form mesoderm, endoderm, and ectoderm.
- Organogenesis begins during weeks three to eight, with the formation of the spinal cord, brain, and heart.
Role of Placenta
- The placenta exchanges materials between the mother and embryo, with the chorion forming finger-like chorionic villi that extend into the endometrium.
- The embryo's blood and the mother's blood remain separated, but oxygen and nutrients diffuse from the mother to the embryo, and carbon dioxide and wastes diffuse from the embryo to the mother.
Excretory System
Osmoregulation
- Osmoregulation is the process of maintaining blood osmolarity within strict limits to prevent dehydration or overhydration.
- Dehydration can cause low blood pressure, dizziness, and confusion, while excess water can cause headaches, nausea, and vomiting.
Nephrons
- The kidneys filter blood and produce urine through nephrons, which are packed together in the renal cortex and medulla.
- Each nephron has two major parts: the renal corpuscle and the renal tubule.
- The renal corpuscle pressure-filters the blood and collects the resulting fluid, called filtrate.
- The renal tubule conducts the filtrate as it is converted to urine, with the distal tubule and collecting duct regulating water reabsorption to prevent dehydration.
Urine Formation
- The key to producing concentrated urine lies in the elevated solute concentration of the surrounding fluid in the renal medulla.
- The collecting duct carries urine through increasingly concentrated interstitial fluid, causing water to leave the urine and enter the interstitial fluid by osmosis, resulting in concentrated urine.
The Placenta and Antibodies
- The placenta selectively transports certain antibodies from mother to embryo, especially late in pregnancy, to defend the newborn against disease.
- The placenta isolates the fetus from many assaults, but does not provide complete protection; some disease-causing organisms and harmful chemicals can pass through.
- The placenta allows exchange of wastes and nutrients between fetal capillaries and maternal blood pools, while keeping the fetal and maternal blood supplies separate.
- The umbilical arteries carry deoxygenated blood from the fetus to the placenta, and the umbilical vein carries oxygenated blood back to the fetus.
The Human Urinary System
- Urinary systems produce and eliminate urine, a watery fluid containing waste products from proteins, ions, and other water-soluble nutrients, and certain foreign substances.
- Urinary systems play two major roles in most animals: excreting cellular wastes and maintaining homeostasis.
Urinary Systems Excrete Cellular Wastes
- Excretion is a general term that encompasses the elimination of any form of waste from the body.
- Urinary systems excrete cellular wastes, primarily nitrogenous wastes (ammonia, urea, and uric acid).
The Mammalian Urinary System
- The mammalian urinary system consists of the paired kidneys and ureters, as well as a single bladder and urethra.
- Osmoregulation is the process of maintaining blood osmolarity (the concentration of ions and other solutes in the blood plasma) within strict limits.
- If a person consumes excess water or becomes dehydrated, it can lead to serious health issues (headaches, nausea, seizures, coma, and death).
An Individual Nephron and Its Blood Supply
- Nephrons in the kidneys filter blood and produce urine.
- The entire blood volume passes through the kidneys about 60 times daily, allowing them to fine-tune its composition.
- Each kidney contains roughly 1 million microscopic urine-forming units called nephrons.
- Nephrons have two major parts: the renal corpuscle and the renal tubule.
The Renal Corpuscle and Renal Tubule
- The renal corpuscle is responsible for pressure-filtering the blood and collecting the resulting fluid, called filtrate.
- The renal corpuscle consists of two parts: the glomerulus and the glomerular capsule.
- The glomerulus is a knot of exceptionally porous capillaries that allow water and small molecules dissolved in the blood plasma to ooze out as blood flows through them.
- The glomerular capsule captures the filtrate.
- The filtrate then enters the renal tubule, which conducts the filtrate as it is converted to urine.
- The renal tubule consists of three parts: the proximal tubule, the nephron loop, and the distal tubule.
Blood Vessels Support the Nephron's Role in Filtering the Blood
- Blood is carried to the kidney by the renal artery, which gives rise to thousands of microscopically narrow arterioles.
- Each arteriole supplies blood to a nephron.
- The arteriole branches to form the capillaries of the glomerulus, which empty into an outgoing arteriole.
- The outgoing arteriole gives rise to peritubular capillaries, which form a network surrounding the renal tubule.
- The peritubular capillaries conduct the blood into a venule that joins the renal vein.
How Is Urine Formed?
- Urine is produced in the nephrons of the kidneys by three processes: filtration, reabsorption, and secretion.
- As urine is formed, dissolved substances move between the parts of the nephron and the interstitial fluid that surrounds these structures.
Filtration Removes Small Molecules and Ions from the Blood
- Filtration, the first step in urine formation, occurs when fluid is forced by blood pressure through the walls of the nephron's glomerular capillaries.
- Two factors facilitate glomerular filtration: the glomerular capillaries are far more porous than most other capillaries, and the arterioles that collect blood from the capillaries are narrower than the arterioles that supply them, creating an unusually high pressure within the glomerular capillaries.
- As a result, about 20% of the blood's fluid, along with its small dissolved molecules, is forced out through the glomerular capillary walls.
- Blood cells and plasma proteins, which are too large to penetrate the capillary walls, remain in the blood.
Reabsorption Returns Important Substances to the Blood
- Reabsorption returns to the blood nearly all the water, ions (Na+, Cl-, K+, Ca2+, HCO3-), and organic nutrients such as vitamins, glucose, and amino acids that were previously removed during filtration.
- The reabsorbed molecules move by diffusion or active transport through the walls of the renal tubule and into the peritubular capillaries, which return them to the bloodstream.
Secretion Actively Transports Substances into the Renal Tubule for Excretion
- Secretion, which occurs mainly through active transport, moves wastes and excess ions from the blood into the renal tubule.
- Secreted substances include excess K+ and H+, small quantities of ammonia, some medicinal and recreational drugs or their breakdown products, as well as certain food additives and pesticides.
Concentration of Urine Occurs in the Distal Tubule and Collecting Duct
- When the filtrate enters the distal tubule, about 80% of its water has already been reabsorbed in the proximal tubule and nephron loop, but the filtrate is still considerably more dilute than the surrounding interstitial fluid in the renal cortex.
- From this point on, additional reabsorption of water is precisely regulated to maintain the blood's osmolarity within narrow limits.
- If fluid intake has been high, more water will be left behind in the filtrate, and watery urine will be produced until the normal blood volume is restored.
- If fluid intake has been low, concentrated urine will be produced.
Fertilization
- Fertilization produces a diploid zygote through the union of sperm and egg.
- Men produce sperm continuously, while women ovulate about once a month.
- During fertilization, sperm move through the cervix, uterus, and uterine tubes, where they can live for 2-4 days.
- The egg is surrounded by accessory follicle cells (corona radiata) and a jelly-like zona pellucida, which act as barriers to sperm.
- Sperm release enzymes to weaken these barriers, allowing a single sperm to fertilize the egg.
- Only a few hundred sperm out of the millions deposited in the vagina reach the uterine tube, and only one fertilizes the egg.
Cell Differentiation, Gastrulation, and Organogenesis
- These processes occur during the first two months of development.
- Fertilization typically takes place in the uterine tube.
Structure and Blood Supply of the Human Kidney
- The human kidney is a fist-sized organ located at waist level on either side of the spinal column.
- The outermost layer is the renal cortex, beneath which lies the renal medulla (kidney marrow).
- The renal medulla surrounds the renal pelvis (kidney bucket), which collects and conducts urine into the ureter.
- The ureter is a muscular tube that propels urine into the bladder.
- The bladder is a hollow, muscular chamber that stores and collects urine.
Urine Formation and Excretion
- Urine is produced in the nephrons of the kidneys through three processes: filtration, reabsorption, and secretion.
- Filtration occurs in the renal corpuscle, where the arteriole branches into capillaries.
- Reabsorption occurs mainly in the proximal tubule, where water and essential molecules are returned to the blood.
- Secretion occurs mainly in the proximal tubule, where wastes and excess ions are actively transported into the renal tubule.
- The distal tubule fine-tunes blood composition by regulating reabsorption and secretion to maintain homeostasis.
- Concentrated urine is produced in the distal tubule and collecting duct through precise regulation of water reabsorption.
Osmoregulation and Urine Concentration
- The kidney regulates water balance by producing concentrated urine to conserve water.
- The nephron loop produces a high concentration of salt ions (Na+ and Cl-) in the interstitial fluid, which helps the kidney produce concentrated urine.
- The collecting duct becomes more permeable to water when fluid intake is low, allowing water to leave the urine by osmosis and return to the blood.
- The elevated solute concentration of the surrounding fluid in the renal medulla enables the production of concentrated urine.
Placenta and Fetus
- The placenta allows exchange of wastes and nutrients between fetal capillaries and maternal blood pools, while keeping the fetal and maternal blood supplies separate.
- The umbilical arteries carry deoxygenated blood from the fetus to the placenta, and the umbilical vein carries oxygenated blood back to the fetus.
- Certain antibodies are selectively transported across the placenta from mother to embryo, especially late in pregnancy, and play an important role in defending the newborn infant against disease.
- The placenta does not provide complete protection: some disease-causing organisms and many harmful chemicals can pass through the placenta.
Human Urinary System
- Urinary systems are organ systems that produce and eliminate urine, which contains waste products from proteins, ions, and other water-soluble nutrients in excess of the body's needs, and certain foreign substances.
- Urinary systems play two major roles in most animals: they excrete cellular wastes and help maintain homeostasis.
- The mammalian urinary system consists of the paired kidneys and ureters, as well as a single bladder and urethra.
Osmoregulation
- Osmoregulation is the process of maintaining blood osmolarity (the concentration of ions and other solutes in the blood plasma) within very strict limits.
- If a person consumes excess water, the surplus water in the blood will move by osmosis into the interstitial fluid and then into cells, causing them to swell.
- If a person becomes dehydrated, blood osmolarity increases and blood volume decreases, leading to low blood pressure, dizziness, and confusion.
Nephron and Blood Supply
- Each kidney contains roughly 1 million microscopic urine-forming units called nephrons.
- Nephrons are packed together in the renal cortex, with a thin extension of each nephron extending into the renal medulla.
- Each nephron has two major parts: the renal corpuscle and the renal tubule.
- The renal corpuscle is responsible for pressure-filtering the blood and collecting the resulting fluid, called filtrate.
- The renal tubule consists of three parts: the proximal tubule, the nephron loop (also called the loop of Henle), and the distal tubule.
Urine Formation
- Urine is produced in the nephrons of the kidneys by three processes: filtration, reabsorption, and secretion.
- Filtration removes small molecules and ions from the blood, including about 20% of the blood's fluid and small dissolved molecules.
- Reabsorption returns to the blood nearly all the water, ions, and organic nutrients that were previously removed during filtration.
- The collecting duct carries urine through increasingly concentrated interstitial fluid within the renal medulla, allowing water to leave the urine and enter the interstitial fluid by osmosis, producing concentrated urine.
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Description
A biology quiz covering the process of fertilization, implantation, and the role of the placenta in reproduction. Topics include sperm and egg nuclei union and human reproductive cycles.