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Musculoskeletal Disorders: Hypocalcemia, Hypercalcemia, Osteoporosis, and Gout

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Musculoskeletal Disorders: Hypocalcemia, Hypercalcemia, Osteoporosis, and Gout

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Questions and Answers

What is the primary cause of pain and inflammation in patients with gout?

Calcium buildup in the joints
GI toxicity
Uric crystals accumulation in the joints (correct)
Bone marrow suppression

What is the therapeutic class of Colchicine?

Antigout (correct)
Antidiarrheal
Antihypertensive
Anti-inflammatory

Why is Colchicine reserved for certain clients?

It is only effective in treating chronic gout
It has a very narrow safety margin (correct)
It is a prototype drug
It can only be administered intravenously

What is the primary action of Colchicine in treating gout?

Decreasing inflammation caused by gout (B) Signup and view all the answers

What is the recommended route of administration for Colchicine?

Oral administration with meals and a full glass of water (C) Signup and view all the answers

What is the condition characterized by weakened bones that are spongy and less dense?

Osteoporosis (C) Signup and view all the answers

What is the primary mechanism of action of calcium salts in treating hypocalcemia?

Suppressing the activity of osteoclasts to decrease bone resorption (B) Signup and view all the answers

Why must alendronate be taken on an empty stomach with a full glass of water?

To decrease the risk of esophageal irritation (B) Signup and view all the answers

What is the primary reason for taking hydroxychloroquine with milk?

To reduce the risk of gastrointestinal disturbances (D) Signup and view all the answers

What is the primary adverse effect of methotrexate that requires close monitoring?

Bone marrow suppression (D) Signup and view all the answers

What is the primary mechanism of action of xanthine oxidase inhibitors?

Inhibiting the production of uric acid in the body (D) Signup and view all the answers

Why is it essential to encourage 2-3 liters of fluid intake when taking xanthine oxidase inhibitors?

To reduce the risk of kidney damage (B) Signup and view all the answers