7 Questions
How many antibodies does IgA have, and how many antigen-binding sites does it have?
2 antibodies, 4 antigen-binding sites
What is the function of J chain in secretory IgA synthesis and transport?
Binding to IgA in plasma cells
Which function is unique to sIgA compared to IgG?
Immune exclusion
What is a function carried out only by IgG, not by sIgA?
Opsonisation
What do mucosal T cells help maintain?
Environment that doesn't respond to commensal microbiota
Which two factors play key roles in regulating T cell responses?
TGF-b and Retinoic acid
What is the purpose of oral tolerance?
"State of immune non-responsiveness by oral administration of antigens"
Test your knowledge on the main route of entry for infectious microorganisms, the presence of resident microflora at mucosal epithelia, and the differences between systemic and mucosal environments. Challenge yourself with reasons why mucosal surfaces are important for immune responses.
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