Motor Control and Reflexes Quiz
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Questions and Answers

What type of muscle do alpha motor neurons primarily innervate?

  • Cardiac muscle
  • Smooth muscle
  • Adipose tissue
  • Skeletal muscle (correct)
  • Where are the cell bodies of motor neurons located?

  • Thalamus
  • Cerebral cortex
  • Dorsal horn of the spinal cord
  • Ventral horn of the spinal cord (correct)
  • Which reflex is classified as monosynaptic?

  • Withdrawal reflex
  • Stretch reflex (correct)
  • Inverse stretch reflex
  • Flexion withdrawal reflex
  • What function do spinal interneurons serve concerning movements?

    <p>Coordinate complex movements and provide proprioceptive feedback (C)</p> Signup and view all the answers

    Which statement about spinal reflexes is true?

    <p>Spinal reflexes can be overridden. (A)</p> Signup and view all the answers

    What does the size of body structures in the primary motor cortex indicate?

    <p>The number of neurons dedicated to motor control (C)</p> Signup and view all the answers

    Which cortices are involved in the voluntary control of movement?

    <p>Premotor cortex and primary motor cortex (A)</p> Signup and view all the answers

    What is the primary function of the middle level in motor control?

    <p>Correction of errors during movement execution (A), Integration of sensory inputs and motor command (B), Execution of individual muscle contractions (C)</p> Signup and view all the answers

    What describes the somatotopic map of the primary motor cortex?

    <p>It reflects the degree of skill required for different body movements (B)</p> Signup and view all the answers

    Which component of movement is considered 'involuntary' despite being part of voluntary movements?

    <p>Corrections based on real-time feedback (D)</p> Signup and view all the answers

    Which pathway is primarily responsible for controlling voluntary, skilled movements?

    <p>Corticospinal pathway (A)</p> Signup and view all the answers

    What is the primary role of the extrapyramidal pathway?

    <p>Regulation of trunk and postural muscles (B)</p> Signup and view all the answers

    Which condition is characterized by decreased dopamine input to the basal nuclei?

    <p>Parkinson disease (D)</p> Signup and view all the answers

    Which of the following is a symptom of spasticity resulting from damage to descending pathways?

    <p>Constant muscle contraction (D)</p> Signup and view all the answers

    What term describes the resistance of skeletal muscle to stretch under normal conditions?

    <p>Muscle tone (B)</p> Signup and view all the answers

    What characterizes hyperkinetic disorder?

    <p>Excessive motor movements (A)</p> Signup and view all the answers

    Which of the following describes bradykinesia?

    <p>Slowed movements (A)</p> Signup and view all the answers

    Which condition results in jerky, random involuntary movements of limbs and face?

    <p>Choreiform movements (B)</p> Signup and view all the answers

    Which disease is known for causing widespread neuronal loss in the basal nuclei due to a genetic mutation?

    <p>Huntington disease (A)</p> Signup and view all the answers

    Which of the following describes dysmetria?

    <p>Inability to target movements correctly (C)</p> Signup and view all the answers

    What is the role of the cerebellum in motor control?

    <p>Receiving sensory information for balance and coordination (D)</p> Signup and view all the answers

    Which of the following is NOT a deficit associated with cerebellar damage?

    <p>Muscle weakness (C)</p> Signup and view all the answers

    What does the magnitude of the withdrawal reflex depend on?

    <p>The magnitude of the pain stimulus (C)</p> Signup and view all the answers

    Which statement correctly describes the ipsilateral response in the withdrawal reflex?

    <p>Flexor muscles contract while extensor muscles relax (A)</p> Signup and view all the answers

    What primary function do muscle spindles serve in the body?

    <p>Reporting muscle length (B)</p> Signup and view all the answers

    What is the role of interneurons in the withdrawal reflex?

    <p>They act as connectors between sensory input and motor output (D)</p> Signup and view all the answers

    Which characteristic is true for the contralateral response in the withdrawal reflex?

    <p>Flexor muscles relax while extensor muscles contract (A)</p> Signup and view all the answers

    What type of muscle fibers do Golgi tendon organs communicate with?

    <p>Extrafusal muscle fibers (C)</p> Signup and view all the answers

    What is the primary role of Ia afferent fibers in muscle spindles?

    <p>Detecting changes in muscle length (B)</p> Signup and view all the answers

    What does the term 'irradiation' refer to in the context of the withdrawal reflex?

    <p>The increase in reflex response with stronger stimuli (C)</p> Signup and view all the answers

    Which of the following describes the afterdischarge phenomenon?

    <p>The response continues even after the pain stimulus ceases (D)</p> Signup and view all the answers

    Which reflex is responsible for protecting limbs from injury?

    <p>Withdrawal reflex (D)</p> Signup and view all the answers

    What type of reflex is categorized as polysynaptic?

    <p>Reflex that requires multiple neurons and synapses (D)</p> Signup and view all the answers

    What muscle spindle characteristic contributes to its sensitivity?

    <p>Intrafusal fibers (A)</p> Signup and view all the answers

    Which of the following best describes the function of the flexor withdrawal reflex?

    <p>To initiate a protective response to harmful stimuli (D)</p> Signup and view all the answers

    What do Golgi tendon organs primarily report?

    <p>Muscle tension (C)</p> Signup and view all the answers

    Which part of the brain plays a role in initiating movement based on sensory information?

    <p>Cerebral cortex (A)</p> Signup and view all the answers

    What is the primary function of gamma motor neurons?

    <p>Innervate intrafusal muscle spindle (B)</p> Signup and view all the answers

    Which reflex is specifically responsible for controlling muscle tension?

    <p>Inverse stretch reflex (A)</p> Signup and view all the answers

    In the context of spinal reflexes, which statement is true regarding monosynaptic and polysynaptic reflexes?

    <p>Monosynaptic reflexes do not involve interneurons. (C)</p> Signup and view all the answers

    Which of the following accurately describes the role of spinal interneurons?

    <p>They coordinate complex movements through voluntary feedback. (A)</p> Signup and view all the answers

    What defines the withdrawal reflex in terms of its properties?

    <p>It is a protective reflex that responds to harmful stimuli. (A)</p> Signup and view all the answers

    What is the primary function of the amygdala within the limbic system?

    <p>Processing and regulating emotions (A)</p> Signup and view all the answers

    Which neurotransmitters are commonly targeted in the treatment of mood disorders?

    <p>Serotonin and norepinephrine (A)</p> Signup and view all the answers

    What is the role of the hippocampus in learning processes?

    <p>Consolidation of short-term memories into long-term memories (C)</p> Signup and view all the answers

    What is typically observed in a person with aphasia?

    <p>Difficulty in articulating or comprehending language (D)</p> Signup and view all the answers

    Which type of muscle action is characterized by the contraction of flexor muscles while extensor muscles relax?

    <p>Flexion (C)</p> Signup and view all the answers

    Which condition is often characterized by hallucinations and delusions?

    <p>Schizophrenia (C)</p> Signup and view all the answers

    What does reciprocal innervation of muscles ensure during movement?

    <p>Balanced contraction and relaxation of flexor and extensor muscles (D)</p> Signup and view all the answers

    Which brain region is primarily responsible for language comprehension?

    <p>Wernicke’s area (C)</p> Signup and view all the answers

    Which of the following statements accurately describes the contralateral response in the withdrawal reflex?

    <p>Extensor muscle contraction takes place. (B), Flexor muscle relaxation occurs. (C)</p> Signup and view all the answers

    What is the primary characteristic of the withdrawal reflex regarding its synaptic nature?

    <p>It is a polysynaptic reflex. (C)</p> Signup and view all the answers

    How does the magnitude of the withdrawal reflex respond to varying intensities of a pain stimulus?

    <p>It increases with the strength of the stimulus. (B)</p> Signup and view all the answers

    What phenomenon describes the maintained response after the termination of a stimulus in the withdrawal reflex?

    <p>Afterdischarge. (D)</p> Signup and view all the answers

    What role do interneurons play in the withdrawal reflex?

    <p>They connect sensory inputs to motor outputs. (D)</p> Signup and view all the answers

    Which statement about irradiation in the context of the withdrawal reflex is true?

    <p>It indicates enhanced response rates with increased stimulus intensity. (A)</p> Signup and view all the answers

    What follows the activation of sensory neurons in the pathway of the withdrawal reflex?

    <p>Integration with motor neuron activation pathways. (B)</p> Signup and view all the answers

    What best describes the feedback loops involved in the withdrawal reflex?

    <p>They enable sustained reflex action post-stimulus. (D)</p> Signup and view all the answers

    What aspect of consciousness is measured by neural activity near the scalp?

    <p>State of consciousness level (A)</p> Signup and view all the answers

    Which of the following is true regarding EEG measurement?

    <p>Frequency relates to levels of responsiveness (A)</p> Signup and view all the answers

    What physiological change occurs during REM sleep?

    <p>Increased inhibitions of skeletal muscle activity (A)</p> Signup and view all the answers

    Which structure in the brain is involved in regulating circadian rhythms?

    <p>Preoptic area of the hypothalamus (D)</p> Signup and view all the answers

    In motivational psychology, motivation is best described as a drive towards what?

    <p>Goal-directed behavior (A)</p> Signup and view all the answers

    What primary neurotransmitter is involved in the mesolimbic dopamine pathway?

    <p>Dopamine (C)</p> Signup and view all the answers

    What neuron activity is associated with increased histamine during sleep?

    <p>Aminergic neurons (C)</p> Signup and view all the answers

    Continuous activation of reward-related brain areas is linked to which phenomenon?

    <p>Self-stimulation experiments (D)</p> Signup and view all the answers

    What pattern characterizes low amplitude and high frequency brain activity?

    <p>Awake and alert state (B)</p> Signup and view all the answers

    Which of the following best describes the emotional experiences associated with consciousness?

    <p>They accompany conscious experiences (A)</p> Signup and view all the answers

    What is the primary function of muscle spindles?

    <p>Detect muscle length. (B)</p> Signup and view all the answers

    Which type of muscle fibers do Golgi tendon organs respond to?

    <p>Extrafusal fibers. (B)</p> Signup and view all the answers

    What response is activated by the Golgi tendon organ when there is increased muscle tension?

    <p>Excitation of motor neurons in the ipsilateral flexor. (B), Inhibition of motor neurons innervating the ipsilateral extensor. (D)</p> Signup and view all the answers

    What type of afferent fibers are responsible for reporting information from the Golgi tendon organ?

    <p>Ib afferents. (B)</p> Signup and view all the answers

    What is the characteristic of Ia primary afferent fibers related to muscle spindles?

    <p>Detect changes in muscle length. (B)</p> Signup and view all the answers

    The stretch reflex primarily controls which aspect of muscle function?

    <p>Muscle length. (B)</p> Signup and view all the answers

    Which of the following best describes the relationship between muscle spindles and extrafusal muscle fibers?

    <p>They are located in parallel with one another. (B)</p> Signup and view all the answers

    What is the primary purpose of the withdrawal reflex?

    <p>To protect limbs from injury (B)</p> Signup and view all the answers

    Which statement accurately describes the stretch reflex?

    <p>It is responsible for controlling muscle length. (D)</p> Signup and view all the answers

    How do gamma motor neurons contribute to muscle spindle sensitivity?

    <p>By activating intrafusal fibers to maintain sensitivity (D)</p> Signup and view all the answers

    What effect does the activation of the primary afferent fibers have during the stretch reflex?

    <p>Excitation of motor neurons innervating the extensor (D)</p> Signup and view all the answers

    Which type of reflex is classified as polysynaptic?

    <p>Withdrawal reflex (D)</p> Signup and view all the answers

    What is the role of intrafusal fibers in the muscle spindle?

    <p>To provide sensory information about muscle length (B)</p> Signup and view all the answers

    Which type of stretch reflex is primarily responsible for knee jerking?

    <p>Monosynaptic stretch reflex (C)</p> Signup and view all the answers

    What is the consequence of prolonged muscle shortening on muscle spindle activity?

    <p>Decreased spindle responsiveness (D)</p> Signup and view all the answers

    What initiates the activation of the muscle spindle during a stretch reflex?

    <p>Change in muscle length (A)</p> Signup and view all the answers

    The inverse stretch reflex primarily regulates which aspect of muscle function?

    <p>Muscle tension (D)</p> Signup and view all the answers

    Flashcards

    Motor Neurons

    Neurons that carry signals from the central nervous system to muscles, causing movement.

    Alpha motor neurons

    Motor neurons that innervate skeletal muscles.

    Withdrawal Reflex

    A reflex that quickly moves a limb away from a painful stimulus.

    Stretch Reflex

    A reflex that maintains muscle length and posture.

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    Spinal Reflexes

    Automatic, involuntary movements controlled by the spinal cord. Examples are withdrawal, stretch, and inverse stretch reflexes.

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    Ipsilateral Response

    The reflex response occurs on the same side (same) as the stimulus.

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    Contralateral Response

    The reflex response occurs on the opposite side (opposite) of the stimulus, like in cross extensor reflex

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    Polysynaptic Reflex

    A reflex arc involving multiple synapses (i.e. interneurons) between sensory input and motor output.

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    Irradiation

    Increased reflex response with stronger stimulus, involving additional motor unit recruitment.

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    Afterdischarge

    Continued reflex response after the stimulus ends due to spinal feedback.

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    Cross Extensor Reflex

    A contralateral response in which the extensor muscle contracts on the opposite side to the flexor muscle contracting on the same side.

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    Magnitude of Response

    The strength or intensity of the withdrawal reflex, which is proportional to the stimulus strength.

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    Extrapyramidal System

    A network of brain structures involved in controlling involuntary movements, particularly those related to posture and body balance.

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    Muscle Spindle

    A sensory receptor within muscles that detects changes in muscle length, sending feedback to the nervous system about muscle stretch.

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    Golgi Tendon Organ

    A sensory receptor located within tendons that detects muscle tension, sending signals to the nervous system.

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    Somatotopic Map

    A representation of the body in the primary motor cortex, where specific areas of the cortex control specific muscle groups.

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    What is the relationship between the size of a body structure in the primary motor cortex and the skill required to control it?

    The larger the representation of a body structure in the primary motor cortex, the more neurons are dedicated to controlling that area, and the more fine-grained and skillful the movement is.

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    Ia Afferent

    Sensory nerve fibers that carry information about changes in muscle length from the muscle spindle's nuclear bag fibers to the spinal cord.

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    II Afferent

    Sensory nerve fibers that carry information about static muscle length from the muscle spindle's nuclear chain fibers to the spinal cord.

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    Intrafusal Fibers

    Specialized muscle fibers within the muscle spindle that maintain its sensitivity and responsiveness.

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    Alpha-Gamma Coactivation

    The simultaneous activation of alpha motor neurons (controlling extrafusal muscle fibers) and gamma motor neurons (controlling intrafusal muscle fibers), ensuring the muscle spindle remains sensitive during muscle contraction.

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    Inverse Stretch Reflex

    A reflex that inhibits muscle contraction when excessive tension is detected by the Golgi tendon organ.

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    Ib Afferent

    Sensory nerve fibers that carry information about muscle tension from the Golgi tendon organ to the spinal cord.

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    Corticospinal Tract

    A direct pathway from the motor cortex to the spinal cord that controls skilled voluntary movements, primarily in the extremities, especially the hands and feet.

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    Extrapyramidal Tract

    A set of indirect pathways originating in the brainstem that control posture, balance, and walking, primarily affecting trunk and postural muscles.

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    Muscle Tone

    The resistance of a muscle to passive stretch, indicating its state of readiness and tension.

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    Hypertonia & Spasticity

    Increased muscle tone, often accompanied by exaggerated reflexes, resulting from damage to descending motor pathways.

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    Rigidity

    Constant muscle contraction, resulting in stiffness throughout the range of motion, often due to damage to descending motor pathways.

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    Hypotonia & Atrophy

    Decreased muscle tone and loss of muscle mass, often due to damage to motor neurons.

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    Basal Nuclei (Ganglia)

    A group of brain structures that play a critical role in planning and executing movements, modulating motor commands, and controlling muscle tone.

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    Parkinson's Disease

    A movement disorder characterized by a lack of dopamine in the basal nuclei, leading to tremors, rigidity, slow movement, and difficulty initiating movement.

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    Hyperkinetic disorder

    A condition characterized by excessive, involuntary muscle movements.

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    Choreiform movements

    Jerky, random, involuntary movements of the limbs and face.

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    Asynergia

    Difficulty coordinating movements, resulting in broken-down, disjointed movements.

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    Dysmetria

    Inaccurate movements, often overshooting or undershooting the intended target.

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    Ataxia

    Lack of coordination and control of muscle movements, leading to unsteady gait and clumsiness.

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    State of consciousness

    A person's level of alertness or awareness at any given time, ranging from fully awake to deep sleep.

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    Conscious experience

    The subjective, personal experience of thoughts, feelings, desires, and perceptions. It's what makes you aware of yourself and your surroundings.

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    EEG

    A tool used to measure the electrical activity in the brain, often used to diagnose epilepsy or sleep disorders.

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    Sleep Stages

    Different phases of sleep characterized by unique brainwave patterns and physiological changes.

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    REM Sleep

    A sleep stage marked by rapid eye movements, vivid dreams, and muscle paralysis.

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    Circadian Rhythm

    The body's natural 24-hour cycle that regulates sleep-wake patterns, hormone release, and body temperature.

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    Motivation

    The internal drive that pushes us to act in a certain way, often directed towards achieving a goal.

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    Emotion

    Our subjective feelings and responses to events or situations.

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    Mesolimbic dopamine pathway

    A brain circuit associated with reward, pleasure, and motivation, often implicated in addiction.

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    Self-stimulation experiments

    Studies where animals are given the ability to stimulate their own brains, revealing how certain brain areas are involved in reward and motivation.

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    Limbic System

    A group of brain structures involved in processing emotions, memory, and motivation. It plays a crucial role in our emotional responses, learning, and behavior.

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    Hippocampus

    A part of the limbic system critical for forming new memories and transferring them from short-term to long-term memory. It is also involved in spatial navigation.

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    Amygdala

    A part of the limbic system involved in processing emotions, especially fear and anxiety. It plays a crucial role in evaluating threats and triggering appropriate responses.

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    Schizophrenia

    A mental disorder characterized by a range of symptoms including hallucinations, delusions, and impaired cognitive function. It affects how a person thinks, feels, and behaves.

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    Depression

    A mood disorder characterized by persistent sadness, loss of interest, and feelings of hopelessness. It is often associated with decreased activity in the anterior limbic system.

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    Bipolar Disorder

    A mood disorder characterized by extreme shifts in mood, energy, and activity levels, ranging from periods of mania or hypomania to episodes of depression.

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    Broca's Area

    A region in the left hemisphere of the brain primarily responsible for speech production and articulation. Damage to this area can result in difficulty speaking.

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    Wernicke's Area

    A region in the left hemisphere of the brain primarily responsible for language comprehension and understanding spoken and written language. Damage to this area can result in difficulty understanding language.

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    Motor Neurons: What are they?

    Specialised nerve cells that carry signals from the brain and spinal cord to muscles, triggering movement.

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    Alpha Motor Neurons: What do they do?

    They directly control the skeletal muscles (the ones that make you move) by sending signals to make them contract.

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    Gamma Motor Neurons: What's their role?

    They control the muscle spindle, a sensory organ within the muscle that helps to sense changes in muscle length.

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    Spinal Reflexes: What are they?

    Automatic, involuntary responses to stimuli that are controlled by the spinal cord, not the brain. Examples include withdrawal reflexes and stretch reflexes.

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    Withdrawal Reflex: What does it do?

    A reflex that quickly moves a body part away from a painful stimulus to prevent injury.

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    Flexion Withdrawal Reflex

    A reflex that quickly moves a limb away from a painful stimulus.

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    Ipsilateral

    The reflex response occurs on the same side of the body as the stimulus.

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    Contralateral

    The reflex response occurs on the opposite side of the body from the stimulus.

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    Polysynaptic

    A reflex arc involving multiple synapses between the sensory input and motor output.

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    Recruitment

    Increasing the number of motor units involved in a reflex response, leading to a greater contraction force.

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    What are the types of stretch reflex?

    Stretch reflex can be monosynaptic or polysynaptic. Monosynaptic reflexes are simpler and involve only one synapse, while polysynaptic reflexes involve multiple synapses.

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    What is the purpose of gamma motor neurons?

    Gamma motor neurons control the tension within the intrafusal muscle fibers of the muscle spindle, ensuring the spindle remains sensitive during muscle contraction.

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    What are the properties of stretch reflex?

    Stretch reflex resists changes in muscle length, contributing to muscle tone and postural control.

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    Study Notes

    Consciousness

    • State of consciousness: Level of arousal (awake, asleep, etc.)
    • Measured by behavior and brain activity
    • Conscious experience: Thoughts, feelings, desires, ideas, etc.
    • This is the capacity to experience one's existence, rather than just reacting to stimuli like an automaton.
    • A laptop, for example, would not be considered conscious.

    The Electroencephalograph (EEG)

    • Measures the activity of neurons near the scalp in the gray matter of the cortex.
    • Voltage (typically 20-100 microvolts) is measured
    • Frequency is related to responsiveness levels.
    • Amplitude is linked to synchronous neural activity.
    • EEG patterns change during different mental states and sleep stages

    EEGs and Mental States

    • Alpha rhythm: Observed when relaxed with eyes closed, has slow frequencies
    • Beta rhythm: Seen when alert, has fast frequencies

    Stages of Sleep

    • Awake: Characterized by low amplitude, high frequency waves
    • NREM (Non-Rapid Eye Movement) sleep: Slow-wave sleep, has progressively higher amplitude and lower frequency waves as sleep deepens, (stages 1-4). Specifically:
      • Stage 1: Transition to sleep.
      • Stage 2: Light sleep.
      • Stage 3: Deeper sleep.
      • Stage 4: Deepest sleep. (NREM Stages 3 & 4 are sometimes combined).
    • REM (Rapid Eye Movement) sleep: Characterized by low amplitude, high frequency waves, associated with dreaming, temporary skeletal muscle inhibition, rapid eye movements

    Physiological Changes During Sleep

    • Reflects changes in brain activity at each sleep stage
    • During REM sleep, there is an increase in eye movements, and inhibition of skeletal muscle. Also, heart rate and respiration rates increase.
    • Sleep apnea is a sudden reduction in respiration.

    States of Consciousness and Brain Regions

    • Preoptic area of hypothalamus: Plays a critical role in regulating sleep.
    • Suprachiasmatic nucleus (SCN) of the hypothalamus: Regulates the circadian rhythm.
    • Reticular activating System: A critical neural network involved in regulating arousal and consciousness

    Regulating States of Consciousness

    • Aminergic neurons (Norepinephrine, serotonin) and cholinergic neurons (acetylcholine) are active in different states of consciousness.
    • These neurons are influenced by the presence and level of certain neurochemicals
    • Chemical factors are involved in the regulations of states of consciousness.
    • The interplay between these chemicals results in specific states of consciousness.
    • Histamine and GABA are two specific chemicals involved in regulating consciousness.

    Motivation and Emotion

    • Motivation: Produces goal-directed behavior.
    • Emotions: Accompany our conscious experiences.

    Mesolimbic Dopamine Pathway

    • A key part of the brain's reward pathway.
    • Dopamine is the primary neurotransmitter.

    Self-Stimulation Experiments

    • Continuous activation of reward-related areas of the brain.

    Limbic System

    • Involved in emotions
    • Includes the olfactory bulb, hippocampus (memory) and amygdala

    Altered States of Consciousness

    • Schizophrenia: Diverse set of problems in basic cognitive processing, including delusions and hallucinations; affects about one out of every 100 people.
    • Mood disorders:
      • Depression: Decreased activity in the anterior limbic system. Treatments increase serotonin and norepinephrine levels.
      • Bipolar disorder: Swings between mania and depression. Treatments include lithium, which reduces certain synaptic signaling pathways.

    Learning and Memory

    • Declarative memory: Conscious experiences put into words.
      • Short-term: Hippocampus and other temporary lobe structures.
      • Long-term: Many parts of the association cortex.
    • Procedural memory: Skilled behavior.
      • Short-term: Widely distributed.
      • Long-term: Basal nuclei, cerebellum, premotor cortex.
    • Sleep: Plays a role in consolidating short-term memories into long-term memories
    • Hippocampus: Important structure in learning and memory

    Inside the Brain

    • H.M.: Amnesic patient who underwent medial temporal lobe removal affecting different brain areas.

    Language

    • Broca's area: Usually in the left hemisphere; articulation.
    • Wernicke's area: Usually in the left hemisphere; comprehension.
    • Aphasia: Language deficit

    Parietal Damage

    • Sensory neglect: A condition resulting from parietal lobe damage characterized by a reduction in awareness of one side of the body or one side of space.

    When Things Go Wrong

    • Descriptions of cases of brain damage, or brain diseases. Cases are often cited with the use of specific medical terminology.

    Motor Behavior

    • Purposeful or goal-directed: Voluntary and reflexive.

    Muscle Control: Extension vs. Flexion

    • Extension: Extensor muscle contracts, agonist, increases the angle
    • Flexion: Flexor muscle contracts, agonist, decreases the angle
    • Antagonistic muscles have opposing actions during movements

    Reciprocal Innervation of Muscles

    • Coordinated activation and relaxation of flexor and extensor muscles.
    • Maintaining limb position is a balance of flexor and extensor muscle tension.

    Motor Neurons

    • Only excitatory (acetylcholine).
    • Alpha: Innervate skeletal (extrafusal) muscle.
    • Gamma: Innervate muscle spindle (intrafusal) muscle.
    • Cell bodies located in the ventral horn of the spinal cord (spinal nerves).
    • Receive input mainly from interneurons.

    Spinal Afferent (Sensory) and Efferent (Motor) Pathways

    • Sensory information travels up the spinal cord in the dorsal columns.
    • Descending motor commands travel down the spinal cord.
    • Interneurons also are located in different levels throughout the spinal cord.

    Spinal Interneurons

    • Receive inputs from different receptor types involved with movement and sensory information.
    • Involved in complex movements
    • Involved in length monitoring of muscles on both sides of the body
    • Coordinating complex movements

    Spinal Reflexes

    • Withdrawal reflex: Protects limbs from injury.
    • Stretch reflex: Controls muscle length (monosynaptic and polysynaptic).
    • Inverse stretch reflex: Controls muscle tension.
    • Reflexes can be modified, these reflexes can be overridden

    Flexion Withdrawal Reflex

    • Polysynaptic: Involves multiple interneurons.
    • Involves inhibition of ipsilateral extensor, and excitation of ipsilateral flexor.
    • Cross-extensor reflex: Involves inhibition of contralateral flexor, and excitation of contralateral extensor.

    Magnitude of Withdrawal Reflex

    • Depends on the magnitude of the pain stimulus.
    • Recruitment of interneurons increases in response to greater stimuli
    • Feedback loops in the spinal cord are involved in the response

    Properties of Withdrawal Reflex

    • Ipsilateral, contralateral, polysynaptic, irradiation, afterdischarge

    Monosynaptic Stretch Reflex (Knee Jerk)

    • Excitation of motor neuron innervating the ipsilateral extensor.
    • Inhibition of motor neuron innervating the ipsilateral flexor.
    • Activation and stretch receptor causes the reflex

    Muscle Spindle and Golgi Tendon Organ

    • Muscle spindle: Parallel to muscle fibers, reports muscle length, vital for the stretch reflex and muscle length control
    • Golgi tendon organ: In series with muscle fibers, reports muscle tension, involved with the inverse stretch reflex and controlling muscle tension

    Muscle Spindle Properties

    • Reports muscle length.
    • Afferents (la and II): Types of nerve fibers, La (primary) detects changes in muscle length, II (secondary) detects static length.
    • In parallel with extrafusal muscle fibers.
    • Intrafusal fibers: Maintain muscle spindle sensitivity.
    • Alpha-gamma coactivation.

    Response of la (primary) and II (secondary) Afferents

    • la primary: Signals dynamic and some static changes in muscle length.
    • II secondary: Signals static muscle length.

    Muscle Spindles Can Lose Sensitivity

    • Results with voluntary flexion and extension as muscles lengthen and shorten.
    • Muscle spindle collapses leading to reduction in sensitivity.

    Gamma Motor Neurons Maintain Muscle Spindle Sensitivity

    • Alpha-gamma coactivation maintains sensitivity.
    • Intrafusal fibers contract and muscle spindle is stretched.

    Alpha-Gamma Coactivation

    • Motor command, alpha and gamma motor neuron activation.
    • Extra-fusal muscle activation and shortening is linked to maintaining spindle sensitivity.
    • Change in length activates the muscle spindle

    Properties of Stretch Reflex

    • Resists changes in muscle length.
    • Mono- and polysynaptic components.
    • Feedback from muscle spindles.

    Properties of Golgi Tendon Organ

    • Reports muscle tension.
    • In series with extrafusal muscle fibers.
    • Ib afferents.
    • Underlies inverse stretch reflex.

    Motor Control Involves Many Brain Areas

    • Corticospinal pathway: Skilled movements.
    • Extrapyramidal pathway: Trunk and posture.
    • Voluntary movements have an involuntary component.
    • Multiple brain regions are involved with motor control
    • Middle level: Executes individualized muscle contractions. Also makes corrections based on sensory information.
    • Brain stem: Plays a critical role with muscle contraction, and control
    • Cerebellum: Involved with timing, planning, error correction and learning new motor skills.
    • Basal Nuclei: Determine the sequence of movements necessary for the execution of an action
    • Higher Centers: Conscious initiation of movement

    Direct Cortical Control of Movement

    • Corticospinal and extrapyramidal pathways.
    • Crossing of the pathways in the medulla.
    • Involvement with alpha and gamma motor neurons.

    Descending Motor Pathways

    • Corticospinal: Originates in the primary motor cortex, compact and direct to spinal cord, controls contralateral muscles, predominately involved with hands and feet, and skilled voluntary movements
    • Extrapyramidal: Originates from neurons in the brainstem, diffused and indirect via the brainstem, involved in trunk and postural muscles, controls upright posture, balance, and walking

    Muscle Tone

    • Resistance of skeletal muscles to stretch.
    • Normal: Slight and uniform.
    • Damage to descending pathways:
      • Hypertonia: Abnormally high muscle tone
      • Spasticity: Overactive motor reflexes
      • Rigidity: Constant muscle contraction.
    • Damage to motor neurons:
      • Hypotonia: Abnormally low muscle tone
      • Atrophy: Loss of muscle mass
      • Decreased or missing reflexes

    Basal Nuclei (Ganglia)

    • Structure: A group of nuclei located deep within the brain.
    • Function: Involved in regulating movement, muscle tone, and posture.

    Basal Nuclei Movement Disorders

    • Parkinson's disease: Reduced dopamine input to basal nuclei, resulting in akinesia, bradykinesia, muscular rigidity, and resting tremor.
    • Huntington's disease: Widespread loss of neurons in the brain, especially in the basal nuclei, resulting in hyperkinetic disorders, like choreiform movements.

    Deep Brain Stimulation

    • A surgical treatment to help control movement disorders like Parkinson's disease through stimulating specific areas of the brain.

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    Cook Cognitive Motor Slides PDF

    Description

    Test your knowledge on the intricate functions of motor neurons, reflexes, and the motor cortex. This quiz covers key concepts related to voluntary and involuntary movements as well as the pathways involved in motor control. Perfect for students studying neuroscience or physiology!

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