10 Questions
What is the main characteristic of monoclonal antibodies (MAbs)?
They are highly specific
How are monoclonal antibodies (MAbs) produced?
They are produced in vitro by a clone of B cells hybridized with cancerous cells
What is the result of injecting murine monoclonal antibodies (MAbs) produced from mice/rats into humans?
Rapid removal from the blood or destruction of the MAb itself
What is the purpose of using antibody engineering to make a human murine hybrid?
To prevent rapid removal or destruction of the MAb
Which biopharmaceutical product is used for the diagnosis of Oseomyelitis and is murine in origin?
LeukoScan Sulesomab
What is the therapeutic application of Abciximab (Reopro)?
Prevention of platelet aggregation and thrombus formation
What is the purpose of Daclizumab (Zenapax)?
Prevent acute rejection of kidney transplant
What is the function of Alteplase (Activase) in Antibody-Directed Enzyme Prodrug Therapy (ADEPT)?
Activation of plasminogen resulting in dissolution of fibrin clots
What is the therapeutic application of Raptiva Efalizumab?
Treatment for psoriasis in adult patients
'Xolair Omalizumab' is utilized for the treatment of which condition?
Asthma
Test your knowledge on the function and generation of monoclonal antibodies and their therapeutic applications, as well as the immune system's specificity in response to infections.
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