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Monoclonal Antibodies and Immune Technology Quiz

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Monoclonal Antibodies and Immune Technology Quiz

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Questions and Answers

What is the main characteristic of monoclonal antibodies (MAbs)?

They are produced in small quantities

They are variable and non-specific

They are produced in vivo by the immune system

They are highly specific (correct)

How are monoclonal antibodies (MAbs) produced?

They are produced in vitro by a clone of B cells hybridized with cancerous cells (correct)

They are extracted from natural sources such as plants or animals

They are synthesized chemically in a laboratory

They are produced in vivo by the immune system

What is the result of injecting murine monoclonal antibodies (MAbs) produced from mice/rats into humans?

Production of human anti-mouse antibodies

Rapid removal from the blood or destruction of the MAb itself (correct)

Occasional kidney failure

Systemic inflammatory effects

What is the purpose of using antibody engineering to make a human murine hybrid?

To prevent rapid removal or destruction of the MAb (A) Signup and view all the answers

Which biopharmaceutical product is used for the diagnosis of Oseomyelitis and is murine in origin?

LeukoScan Sulesomab (A) Signup and view all the answers

What is the therapeutic application of Abciximab (Reopro)?

Prevention of platelet aggregation and thrombus formation (C) Signup and view all the answers

What is the purpose of Daclizumab (Zenapax)?

Prevent acute rejection of kidney transplant (B) Signup and view all the answers

What is the function of Alteplase (Activase) in Antibody-Directed Enzyme Prodrug Therapy (ADEPT)?

Activation of plasminogen resulting in dissolution of fibrin clots (C) Signup and view all the answers

What is the therapeutic application of Raptiva Efalizumab?

Treatment for psoriasis in adult patients (C) Signup and view all the answers

'Xolair Omalizumab' is utilized for the treatment of which condition?

Asthma (D) Signup and view all the answers