Monoclonal Antibodies and Immune Technology
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Questions and Answers

What are monoclonal antibodies (MAbs)?

  • Antibodies produced in vitro by a clone of B cells hybridized with cancerous cells (correct)
  • Antibodies synthesized in a laboratory using chemical reactions
  • Antibodies generated through exposure to a wide range of antigens
  • Antibodies extracted from natural sources like human or animal immune systems

What is the primary advantage of monoclonal antibodies (MAbs)?

  • High specificity (correct)
  • Low cost production
  • Ability to target multiple antigens simultaneously
  • Natural extraction from immune systems

What is the function of Complementarity Determining Region (CDR) in antibody engineering?

  • Maintaining antibody stability
  • Regulating antibody production
  • Enhancing Fc region functionality
  • Targeting specific antigens (correct)

How are monoclonal antibodies (MAbs) produced?

<p>In vitro by hybridizing B cells with cancerous cells (D)</p> Signup and view all the answers

Which type of monoclonal antibody was used to diagnose Oseomyelitis?

<p>Murine (C)</p> Signup and view all the answers

What is the purpose of Abciximab (Reopro)?

<p>Inhibiting platelet aggregation (C)</p> Signup and view all the answers

What is the function of Daclizumab (Zenapax)?

<p>Preventing acute rejection of kidney transplant (C)</p> Signup and view all the answers

What is the result of injecting murine monoclonal antibodies into humans?

<p>Rapid removal from the blood or destruction of the MAb itself (C)</p> Signup and view all the answers

What is the concept utilized by Alteplase (Activase)?

<p>Antibody-Directed Enzyme Prodrug Therapy (ADEPT) (C)</p> Signup and view all the answers

Which type of monoclonal antibody is Xolair Omalizumab?

<p>Humanized (C)</p> Signup and view all the answers

What are monoclonlonal antibodies (MAbs) primarily known for?

<p>Being highly specific (C)</p> Signup and view all the answers

What is the function of Complementarity Determining Region (CDR) in antibody engineering?

<p>It determines the specificity of the antibody (D)</p> Signup and view all the answers

What is a key advantage of monoclonal antibodies (MAbs)?

<p>They are highly specific (A)</p> Signup and view all the answers

How are monoclonal antibodies (MAbs) produced?

<p>In vitro by a clone of B cells hybridized with cancerous cells (D)</p> Signup and view all the answers

What is the main focus of current antibody engineering efforts?

<p>The variable and Fc regions of the molecule (A)</p> Signup and view all the answers

What is the primary role of the immune system response to an infection?

<p>To discriminate between pathogen species and strains within one species (C)</p> Signup and view all the answers

What makes Monoclonal Antibodies (MAbs) useful?

<p>Their high specificity (D)</p> Signup and view all the answers

What is the function of antibodies in the immune system?

<p>To maintain a balance between response to foreign antigens and tolerance with respect to self-antigens (B)</p> Signup and view all the answers

What is a characteristic feature of Monoclonal Antibodies (MAbs)?

<p>Uniformity (C)</p> Signup and view all the answers

What is one of the main targets for current antibody engineering efforts?

<p>The Fc region of the molecule (B)</p> Signup and view all the answers

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