Monoclonal Antibodies and Immune Technology
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Questions and Answers

What are monoclonal antibodies (MAbs)?

  • Antibodies produced in vitro by a clone of B cells hybridized with cancerous cells (correct)
  • Antibodies synthesized in a laboratory using chemical reactions
  • Antibodies generated through exposure to a wide range of antigens
  • Antibodies extracted from natural sources like human or animal immune systems

    • What is the primary advantage of monoclonal antibodies (MAbs)?

  • High specificity (correct)
  • Low cost production
  • Ability to target multiple antigens simultaneously
  • Natural extraction from immune systems

    • What is the function of Complementarity Determining Region (CDR) in antibody engineering?

  • Maintaining antibody stability
  • Regulating antibody production
  • Enhancing Fc region functionality
  • Targeting specific antigens (correct)

    • How are monoclonal antibodies (MAbs) produced?

    <p>In vitro by hybridizing B cells with cancerous cells</p> Signup and view all the answers

    Which type of monoclonal antibody was used to diagnose Oseomyelitis?

    <p>Murine</p> Signup and view all the answers

    What is the purpose of Abciximab (Reopro)?

    <p>Inhibiting platelet aggregation</p> Signup and view all the answers

    What is the function of Daclizumab (Zenapax)?

    <p>Preventing acute rejection of kidney transplant</p> Signup and view all the answers

    What is the result of injecting murine monoclonal antibodies into humans?

    <p>Rapid removal from the blood or destruction of the MAb itself</p> Signup and view all the answers

    What is the concept utilized by Alteplase (Activase)?

    <p>Antibody-Directed Enzyme Prodrug Therapy (ADEPT)</p> Signup and view all the answers

    Which type of monoclonal antibody is Xolair Omalizumab?

    <p>Humanized</p> Signup and view all the answers

    What are monoclonlonal antibodies (MAbs) primarily known for?

    <p>Being highly specific</p> Signup and view all the answers

    What is the function of Complementarity Determining Region (CDR) in antibody engineering?

    <p>It determines the specificity of the antibody</p> Signup and view all the answers

    What is a key advantage of monoclonal antibodies (MAbs)?

    <p>They are highly specific</p> Signup and view all the answers

    How are monoclonal antibodies (MAbs) produced?

    <p>In vitro by a clone of B cells hybridized with cancerous cells</p> Signup and view all the answers

    What is the main focus of current antibody engineering efforts?

    <p>The variable and Fc regions of the molecule</p> Signup and view all the answers

    What is the primary role of the immune system response to an infection?

    <p>To discriminate between pathogen species and strains within one species</p> Signup and view all the answers

    What makes Monoclonal Antibodies (MAbs) useful?

    <p>Their high specificity</p> Signup and view all the answers

    What is the function of antibodies in the immune system?

    <p>To maintain a balance between response to foreign antigens and tolerance with respect to self-antigens</p> Signup and view all the answers

    What is a characteristic feature of Monoclonal Antibodies (MAbs)?

    <p>Uniformity</p> Signup and view all the answers

    What is one of the main targets for current antibody engineering efforts?

    <p>The Fc region of the molecule</p> Signup and view all the answers

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