Monoclonal Antibodies and Immune Technology

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What are monoclonal antibodies (MAbs)?

Antibodies produced in vitro by a clone of B cells hybridized with cancerous cells (correct)

Antibodies synthesized in a laboratory using chemical reactions

Antibodies generated through exposure to a wide range of antigens

Antibodies extracted from natural sources like human or animal immune systems

What is the primary advantage of monoclonal antibodies (MAbs)?

High specificity (correct)

Low cost production

Ability to target multiple antigens simultaneously

Natural extraction from immune systems

What is the function of Complementarity Determining Region (CDR) in antibody engineering?

Maintaining antibody stability

Regulating antibody production

Enhancing Fc region functionality

Targeting specific antigens (correct)

How are monoclonal antibodies (MAbs) produced?

In vitro by hybridizing B cells with cancerous cells Signup and view all the answers

Which type of monoclonal antibody was used to diagnose Oseomyelitis?

Murine Signup and view all the answers

What is the purpose of Abciximab (Reopro)?

Inhibiting platelet aggregation Signup and view all the answers

What is the function of Daclizumab (Zenapax)?

Preventing acute rejection of kidney transplant Signup and view all the answers

What is the result of injecting murine monoclonal antibodies into humans?

Rapid removal from the blood or destruction of the MAb itself Signup and view all the answers

What is the concept utilized by Alteplase (Activase)?

Antibody-Directed Enzyme Prodrug Therapy (ADEPT) Signup and view all the answers

Which type of monoclonal antibody is Xolair Omalizumab?

Humanized Signup and view all the answers

What are monoclonlonal antibodies (MAbs) primarily known for?

Being highly specific Signup and view all the answers

What is the function of Complementarity Determining Region (CDR) in antibody engineering?

It determines the specificity of the antibody Signup and view all the answers

What is a key advantage of monoclonal antibodies (MAbs)?

They are highly specific Signup and view all the answers

How are monoclonal antibodies (MAbs) produced?

In vitro by a clone of B cells hybridized with cancerous cells Signup and view all the answers

What is the main focus of current antibody engineering efforts?

The variable and Fc regions of the molecule Signup and view all the answers

What is the primary role of the immune system response to an infection?

To discriminate between pathogen species and strains within one species Signup and view all the answers

What makes Monoclonal Antibodies (MAbs) useful?

Their high specificity Signup and view all the answers

What is the function of antibodies in the immune system?

To maintain a balance between response to foreign antigens and tolerance with respect to self-antigens Signup and view all the answers

What is a characteristic feature of Monoclonal Antibodies (MAbs)?

Uniformity Signup and view all the answers

What is one of the main targets for current antibody engineering efforts?

The Fc region of the molecule Signup and view all the answers

Monoclonal Antibodies and Immune Technology

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Questions and Answers

What are monoclonal antibodies (MAbs)?

What is the primary advantage of monoclonal antibodies (MAbs)?

What is the function of Complementarity Determining Region (CDR) in antibody engineering?

How are monoclonal antibodies (MAbs) produced?

Which type of monoclonal antibody was used to diagnose Oseomyelitis?

What is the purpose of Abciximab (Reopro)?

What is the function of Daclizumab (Zenapax)?

What is the result of injecting murine monoclonal antibodies into humans?

What is the concept utilized by Alteplase (Activase)?

Which type of monoclonal antibody is Xolair Omalizumab?

What are monoclonlonal antibodies (MAbs) primarily known for?

What is the function of Complementarity Determining Region (CDR) in antibody engineering?

What is a key advantage of monoclonal antibodies (MAbs)?

How are monoclonal antibodies (MAbs) produced?

What is the main focus of current antibody engineering efforts?

What is the primary role of the immune system response to an infection?

What makes Monoclonal Antibodies (MAbs) useful?

What is the function of antibodies in the immune system?

What is a characteristic feature of Monoclonal Antibodies (MAbs)?

What is one of the main targets for current antibody engineering efforts?

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