Molecular Imaging: In Vivo Nuclear Imaging

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What is the primary goal of in vivo radiation detection?

To develop miniature gamma-ray probes for surgical use

To diagnose and treat diseases using radiopharmaceuticals (correct)

To understand the effects of collimation and scattering on radiation detection

To visualize the intrinsic properties of tissues and organs

What is the primary purpose of radiopharmaceutical administration in in vivo nuclear imaging?

To distinguish between normal and abnormal tissues

To detect radiation emanation from outside the human body

To administer radiation therapy directly to tissues

To assess the distribution of radionuclides in different parts of an organ (correct)

What is the main difference between anatomical/morphological imaging and molecular imaging?

The use of biomarkers in anatomical imaging

The use of radiopharmaceuticals in molecular imaging

The visualization of cellular function in molecular imaging (correct)

The non-invasive nature of anatomical imaging

What is the name of the probe system used for in vivo counting?

NaI (Tl) probe system Signup and view all the answers

What is the usual method of radiopharmaceutical administration in in vivo nuclear imaging?

Intravenous administration Signup and view all the answers

What is the term for the use of very small amounts of radioactive materials to diagnose and treat disease?

Theragnostic Signup and view all the answers

What is the advantage of gamma cameras in in vivo nuclear imaging?

They permit the static and dynamic acquisition of images with better spatial resolution Signup and view all the answers

What is the purpose of using tracers in in vivo nuclear imaging?

To accumulate in tissues over a longer period of time Signup and view all the answers

What is the main application of radiotracer imaging using nuclear medicine techniques?

Molecular imaging Signup and view all the answers

What is the term for the non-invasive visualization of living organisms for research or diagnostic purposes?

In vivo imaging Signup and view all the answers

What is the role of NaI(Tl) or other crystal detectors in in vivo nuclear imaging?

To form an image of the radionuclide distribution Signup and view all the answers

What is the significance of radiopharmaceuticals being specifically made for certain organs or tissues?

To target specific organs or tissues for nuclear imaging or therapy Signup and view all the answers

What is the approximate energy level above which the fraction of γ rays absorbed in tissue-equivalent material becomes negligible?

100 keV Signup and view all the answers

What type of in vivo counting systems are used to measure radioactive concentrations in single organs or localized parts of the body?

Probe systems Signup and view all the answers

What is the primary purpose of a thyroid probe?

To measure the uptake of 131I or 123I in the thyroid gland Signup and view all the answers

What is the typical diameter and thickness of a NaI(Tl) detector used in a thyroid probe?

5 cm in diameter by 5 cm in thickness Signup and view all the answers

What is the primary advantage of probe systems over imaging techniques?

Higher degree of measurement localization Signup and view all the answers

Why are most in vivo counting systems designed to detect γ rays?

Because radiation generally passes through several centimeters of soft tissue to reach the detector Signup and view all the answers