Molecular Genetics of ABO: Advanced Concepts
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Questions and Answers

What is one of the main reasons for normal levels of H substances to be present in saliva?

  • Secretor status (correct)
  • Genetic mutations in the ABO gene
  • Thalassemia
  • Chromosome 9 translocations

How are A and B substances present in secretions?

  • When both A and B genes are present (correct)
  • Regardless of the A and B genes
  • Only when A gene is present
  • Only when B gene is present

Which of the following is NOT mentioned as an association with blood groups in the text?

  • 'Intelligence' in group AB individuals (correct)
  • Hangover in A blood groups
  • 'Good teeth' in group O individuals
  • 'Criminality' in group B blood groups

What term is used to describe the additional acquired pseudoantigens seen during forward grouping as a result of various disease states altering RBC antigens?

<p>Mixed-field agglutination (A)</p> Signup and view all the answers

Which condition has been shown to depress antigen strength, resulting in cells appearing to show mixed-field agglutination?

<p>Thalassemia (C)</p> Signup and view all the answers

What do scientists refer to as 'part of blood group mythology' according to the text?

<p>'Criminality' in group B blood groups (D)</p> Signup and view all the answers

Which of the following disorders is NOT mentioned as being associated with ABH antigens in the text?

<p>'Heart disease' (B)</p> Signup and view all the answers

In terms of blood group serology, what is an important impact of various disease states on RBC antigens?

<p>'Acquired pseudoantigens' (A)</p> Signup and view all the answers

'Tiny agglutinates in a sea of unagglutinated cells' is characteristic of which phenomenon mentioned in the text?

<p>'Mixed-field agglutination' (A)</p> Signup and view all the answers

'Progressively weaker reactions or additional acquired pseudoantigens' can be observed during which process according to the text?

<p>'Forward grouping' (D)</p> Signup and view all the answers

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