10 Questions
What is one of the main reasons for normal levels of H substances to be present in saliva?
Secretor status
How are A and B substances present in secretions?
When both A and B genes are present
Which of the following is NOT mentioned as an association with blood groups in the text?
'Intelligence' in group AB individuals
What term is used to describe the additional acquired pseudoantigens seen during forward grouping as a result of various disease states altering RBC antigens?
Mixed-field agglutination
Which condition has been shown to depress antigen strength, resulting in cells appearing to show mixed-field agglutination?
Thalassemia
What do scientists refer to as 'part of blood group mythology' according to the text?
'Criminality' in group B blood groups
Which of the following disorders is NOT mentioned as being associated with ABH antigens in the text?
'Heart disease'
In terms of blood group serology, what is an important impact of various disease states on RBC antigens?
'Acquired pseudoantigens'
'Tiny agglutinates in a sea of unagglutinated cells' is characteristic of which phenomenon mentioned in the text?
'Mixed-field agglutination'
'Progressively weaker reactions or additional acquired pseudoantigens' can be observed during which process according to the text?
'Forward grouping'
Explore advanced concepts in the molecular genetics of the ABO blood group system, including the identification of over 250 ABO alleles and the structure of the ABO gene on chromosome 9 with its seven exons. Focus on exons 6 and 7, which encode the catalytic domain of ABO glycosyltransferases.
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