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Molecular Genetics of ABO: Advanced Concepts

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Molecular Genetics of ABO: Advanced Concepts

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Questions and Answers

What is one of the main reasons for normal levels of H substances to be present in saliva?

Secretor status (correct)

Genetic mutations in the ABO gene

Thalassemia

Chromosome 9 translocations

How are A and B substances present in secretions?

When both A and B genes are present (correct)

Regardless of the A and B genes

Only when A gene is present

Only when B gene is present

Which of the following is NOT mentioned as an association with blood groups in the text?

'Intelligence' in group AB individuals (correct)

Hangover in A blood groups

'Good teeth' in group O individuals

'Criminality' in group B blood groups

What term is used to describe the additional acquired pseudoantigens seen during forward grouping as a result of various disease states altering RBC antigens?

Mixed-field agglutination Signup and view all the answers

Which condition has been shown to depress antigen strength, resulting in cells appearing to show mixed-field agglutination?

Thalassemia Signup and view all the answers

What do scientists refer to as 'part of blood group mythology' according to the text?

'Criminality' in group B blood groups Signup and view all the answers

Which of the following disorders is NOT mentioned as being associated with ABH antigens in the text?

'Heart disease' Signup and view all the answers

In terms of blood group serology, what is an important impact of various disease states on RBC antigens?

'Acquired pseudoantigens' Signup and view all the answers

'Tiny agglutinates in a sea of unagglutinated cells' is characteristic of which phenomenon mentioned in the text?

'Mixed-field agglutination' Signup and view all the answers

'Progressively weaker reactions or additional acquired pseudoantigens' can be observed during which process according to the text?

'Forward grouping' Signup and view all the answers