Pharma- Arrhythmias Q4
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Questions and Answers

2 drugs of class IC drugs?

FP. Flecainide, propafenone.

side effect of flecainide?

can cause sudden death after MI

which drug give additional B-blocker effect?

propafenone. (Ic)

side effect of class Ic drugs (propafenone, Flecainide)?

<p>potent negative inotropic effect, risk of heart failure.</p> Signup and view all the answers

which class of drugs can be used for chemical cardioversion?

<p>class Ic drugs (propafenone, flecainide)</p> Signup and view all the answers

how class II drugs work (beta blockers) and whats their outcomes?

<p>beta blockers bind to beta receptor agonism in heart and block their activity/block NE, EP (sympathetic innervation and nodal APs)&gt;&gt; deploy AP generation in (nodes), also have negative inotropic effect in myocytes due to lower Ca2+ activity.</p> Signup and view all the answers

uses of class II drugs ( beta blockers)?

<p>1- atria tachycardias. 2- reduce mortality following MI 3- reduce arrhythmias due to excessive sympathetic activity.</p> Signup and view all the answers

what r B1-selective drugs and why we call them selective?

<p>(ABM), atenolol, bisoprolol, metoprolol. because they don't affect smooth muscles, they just affect cardiac tissue (inotropic, and chronotropic).</p> Signup and view all the answers

beta blockers drug that is (non-selective.)

<p>propanolol. non-selective&gt;can cause vasodilation.</p> Signup and view all the answers

beta blocker drug that has some class III (K+) activity

<p>Sotalol.</p> Signup and view all the answers

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