Pharma- Arrhythmias Q4

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2 drugs of class IC drugs?

FP. Flecainide, propafenone.

side effect of flecainide?

can cause sudden death after MI

which drug give additional B-blocker effect?

propafenone. (Ic)

side effect of class Ic drugs (propafenone, Flecainide)?

potent negative inotropic effect, risk of heart failure. Signup and view all the answers

which class of drugs can be used for chemical cardioversion?

class Ic drugs (propafenone, flecainide) Signup and view all the answers

how class II drugs work (beta blockers) and whats their outcomes?

beta blockers bind to beta receptor agonism in heart and block their activity/block NE, EP (sympathetic innervation and nodal APs)>> deploy AP generation in (nodes), also have negative inotropic effect in myocytes due to lower Ca2+ activity. Signup and view all the answers

uses of class II drugs ( beta blockers)?

1- atria tachycardias. 2- reduce mortality following MI 3- reduce arrhythmias due to excessive sympathetic activity. Signup and view all the answers

what r B1-selective drugs and why we call them selective?

(ABM), atenolol, bisoprolol, metoprolol. because they don't affect smooth muscles, they just affect cardiac tissue (inotropic, and chronotropic). Signup and view all the answers

beta blockers drug that is (non-selective.)

propanolol. non-selective>can cause vasodilation. Signup and view all the answers

beta blocker drug that has some class III (K+) activity

Sotalol. Signup and view all the answers

Class IC drugs examples

Flecainide and propafenone are examples of Class IC antiarrhythmic drugs.

Flecainide side effect

Flecainide can increase the risk of sudden death after a heart attack (MI).

Propafenone additional effect

Propafenone has an added effect like a beta-blocker, influencing heart function.

Class IC drug side effects

Class IC drugs (flecainide, propafenone) can weaken the heart's pumping ability (negative inotropic effect) and increase the risk of heart failure.