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Questions and Answers
SE of beta blockers?
SE of beta blockers?
1- hypotension>dizziness. 2- fatigue. 3- peripheral vasoconstriction. 4- contraindicated with asthma.
SE of sotalol
SE of sotalol
as it has some class III activity, it may be more potent> TdP risk
how class III (k+) blockers work?
how class III (k+) blockers work?
delay repolarisation (phase 3), extend ERF, lengthen the AP. > negative chronotropic (decrease HR), positive inotropic (increase contractility). effect on myocytes and nodal.
what pharmakinetic issues that class III drugs have? eg (Amiodarone)
what pharmakinetic issues that class III drugs have? eg (Amiodarone)
whats highly effective anti-arrhythmic for chronic and acute use, has some class 1a,2,3 activity?
whats highly effective anti-arrhythmic for chronic and acute use, has some class 1a,2,3 activity?
SE of class III drugs eg (Amiodarone)
SE of class III drugs eg (Amiodarone)
alternatives of the use of Amiodarone (class 3 drug)
alternatives of the use of Amiodarone (class 3 drug)
mechanism of class 4 (ca++9 blockers).
mechanism of class 4 (ca++9 blockers).
what effects class 4 drugs (Ca2+) have on nodal AP?
what effects class 4 drugs (Ca2+) have on nodal AP?
what effects that class 4 drugs (ca2+ blockers) have on myocytes AP?
what effects that class 4 drugs (ca2+ blockers) have on myocytes AP?
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