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Questions and Answers
What happens during the G1 phase of interphase?
What happens during the G1 phase of interphase?
Which phase of the cell cycle involves the duplication of chromosomes?
Which phase of the cell cycle involves the duplication of chromosomes?
What is the main function of the mitotic phase in the cell cycle?
What is the main function of the mitotic phase in the cell cycle?
What is the key feature of eukaryotic cell cycle regulation?
What is the key feature of eukaryotic cell cycle regulation?
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Which phase is the most variable in length in different types of cells?
Which phase is the most variable in length in different types of cells?
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During which phase does duplication of chromosomes occur?
During which phase does duplication of chromosomes occur?
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What is the main function of the G1 phase?
What is the main function of the G1 phase?
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Which phase involves intense metabolic activity and growth despite its misnaming?
Which phase involves intense metabolic activity and growth despite its misnaming?
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What is the last stage of the cell cycle?
What is the last stage of the cell cycle?
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Which phase involves the formation of a mitotic spindle and condensation of chromosomes?
Which phase involves the formation of a mitotic spindle and condensation of chromosomes?
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What occurs during anaphase?
What occurs during anaphase?
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What is the main function of the S phase?
What is the main function of the S phase?
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What is the function of the M phase?
What is the function of the M phase?
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During which phase do the centrosomes move away from each other?
During which phase do the centrosomes move away from each other?
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Which phase involves the movement of centrosomes and extension of microtubules into the nuclear area?
Which phase involves the movement of centrosomes and extension of microtubules into the nuclear area?
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What is the phase for preparation for cell division?
What is the phase for preparation for cell division?
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What is the function of cell division in multicellular eukaryotes?
What is the function of cell division in multicellular eukaryotes?
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What is the typical number of chromosomes in human somatic cells?
What is the typical number of chromosomes in human somatic cells?
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What is the structure of eukaryotic chromosomes?
What is the structure of eukaryotic chromosomes?
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What is the primary reason for packaging DNA into chromosomes?
What is the primary reason for packaging DNA into chromosomes?
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What is the characteristic number of chromosomes in human reproductive cells?
What is the characteristic number of chromosomes in human reproductive cells?
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What is the role of chromosomes during cell division?
What is the role of chromosomes during cell division?
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What is the purpose of eukaryotic cell division?
What is the purpose of eukaryotic cell division?
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What is the accuracy of DNA passage during cell division?
What is the accuracy of DNA passage during cell division?
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What is the length of DNA in a typical human cell?
What is the length of DNA in a typical human cell?
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What is the number of genes carried by a eukaryotic chromosome?
What is the number of genes carried by a eukaryotic chromosome?
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What is the variation in the number of chromosomes in eukaryotic somatic cells among species?
What is the variation in the number of chromosomes in eukaryotic somatic cells among species?
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What is the distribution of identical genetic material to daughter cells during cell division?
What is the distribution of identical genetic material to daughter cells during cell division?
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During cell division, what happens to sister chromatids?
During cell division, what happens to sister chromatids?
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What is the result of mitosis followed by cytokinesis?
What is the result of mitosis followed by cytokinesis?
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When is DNA replication followed by the condensation of chromosomes?
When is DNA replication followed by the condensation of chromosomes?
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What do duplicated chromosomes consist of?
What do duplicated chromosomes consist of?
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What is the portion of a chromatid to either side of the centromere referred to as?
What is the portion of a chromatid to either side of the centromere referred to as?
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What separates the sister chromatids into two chromosomes and distributes them to daughter cells?
What separates the sister chromatids into two chromosomes and distributes them to daughter cells?
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Which phase of the cell cycle includes metabolic activity and growth?
Which phase of the cell cycle includes metabolic activity and growth?
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What reduces the chromosome number from 46 to 23 in gametes?
What reduces the chromosome number from 46 to 23 in gametes?
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What is the result of mitosis?
What is the result of mitosis?
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What is the form of chromosomes when a cell is not dividing?
What is the form of chromosomes when a cell is not dividing?
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What is the role of sister chromatid cohesion?
What is the role of sister chromatid cohesion?
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What is the part of the cell cycle that includes G1, S, and G2 phases?
What is the part of the cell cycle that includes G1, S, and G2 phases?
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What is responsible for the poleward movement of chromosomes during anaphase?
What is responsible for the poleward movement of chromosomes during anaphase?
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During which phase do cohesins holding together sister chromatids get cleaved by an enzyme called separase?
During which phase do cohesins holding together sister chromatids get cleaved by an enzyme called separase?
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Where does the assembly of spindle microtubules start in animal cells?
Where does the assembly of spindle microtubules start in animal cells?
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What is the role of the mitotic spindle in mitosis events?
What is the role of the mitotic spindle in mitosis events?
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What happens to the cell during cytokinesis in animal cells?
What happens to the cell during cytokinesis in animal cells?
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What is the function of nonkinetochore microtubules during mitosis?
What is the function of nonkinetochore microtubules during mitosis?
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When does the cell elongate as nonkinetochore microtubules lengthen?
When does the cell elongate as nonkinetochore microtubules lengthen?
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What occurs during prophase and prometaphase in animal cells?
What occurs during prophase and prometaphase in animal cells?
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What organizes the cell’s microtubules?
What organizes the cell’s microtubules?
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What is the role of kinetochores during prometaphase?
What is the role of kinetochores during prometaphase?
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What happens to spindle microtubules during mitosis?
What happens to spindle microtubules during mitosis?
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What is the region containing material that organizes the cell’s microtubules?
What is the region containing material that organizes the cell’s microtubules?
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Study Notes
Mitotic Spindle and Chromosome Movement in Cell Division
- Mitosis, the division of one nucleus into two genetically identical nuclei, is completed with the cell elongating as nonkinetochore microtubules lengthen
- Cytokinesis in animal cells involves the formation of a cleavage furrow that pinches the cell in two
- The mitotic spindle, consisting of microtubules and associated proteins, plays a crucial role in mitosis events
- Spindle microtubules elongate and shorten through polymerization and depolymerization, respectively
- In animal cells, the assembly of spindle microtubules starts at the centrosome, a region containing material that organizes the cell’s microtubules
- During interphase in animal cells, the single centrosome duplicates, forming two centrosomes, which move apart during prophase and prometaphase
- Each sister chromatid of a duplicated chromosome has a kinetochore, and during prometaphase, some spindle microtubules attach to the kinetochores
- At metaphase, the centromeres of all the duplicated chromosomes are on the metaphase plate, with microtubules overlapping and interacting
- Anaphase begins when cohesins holding together sister chromatids are cleaved by an enzyme called separase, allowing the chromatids to move toward opposite ends of the cell
- Mechanisms involving motor proteins on the kinetochores are responsible for the poleward movement of chromosomes during anaphase
- One mechanism suggests that motor proteins on the kinetochores "walk" the chromosomes along the microtubules, which depolymerize at their kinetochore ends
- Other research has shown that chromosomes are "reeled in" by motor proteins at the.
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Description
Test your understanding of mitotic spindle and chromosome movement in cell division with this quiz. Explore the key events of mitosis, including spindle assembly, kinetochore attachment, metaphase alignment, anaphase separation, and cytokinesis in animal cells.