Micronutrients: Fat-Soluble Vitamins

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Questions and Answers

Which of the following is the earliest symptom associated with Vitamin A deficiency?

  • Xerophthalmia
  • Night blindness (correct)
  • Hemolytic anemia
  • Liver damage

A patient is diagnosed with osteomalacia. Which vitamin deficiency is most likely the cause?

  • Vitamin A
  • Vitamin K
  • Vitamin E
  • Vitamin D (correct)

Which of the following vitamins primarily functions as an antioxidant, protecting cells, especially red blood cells, from oxidative stress?

  • Vitamin E (correct)
  • Vitamin D
  • Vitamin A
  • Vitamin K

Newborns are typically given a Vitamin K injection shortly after birth. What is the primary reason for this practice?

<p>To promote blood clotting (A)</p> Signup and view all the answers

Scurvy, a condition characterized by bleeding gums and poor wound healing, is caused by a deficiency in which vitamin?

<p>Vitamin C (A)</p> Signup and view all the answers

Which of the following vitamins is essential for DNA synthesis and is particularly important during pregnancy to prevent neural tube defects?

<p>Vitamin B9 (Folate) (A)</p> Signup and view all the answers

Pernicious anemia, a condition caused by impaired absorption of Vitamin B12, is most commonly seen in which of the following populations?

<p>Vegetarians and the elderly (C)</p> Signup and view all the answers

A patient presents with fatigue and weakness and is diagnosed with iron-deficiency anemia. Which dietary recommendation would be most effective in increasing iron absorption?

<p>Consuming iron-rich foods with citrus fruits (D)</p> Signup and view all the answers

Individuals with lactose intolerance are at a higher risk of developing a deficiency in which mineral?

<p>Calcium (B)</p> Signup and view all the answers

Which mineral is critical for muscle and nerve function, acts as an enzyme cofactor, and supports bone health?

<p>Magnesium (C)</p> Signup and view all the answers

Endurance athletes who sweat excessively during prolonged exercise are at risk of losing which electrolyte, potentially leading to hyponatremia?

<p>Sodium (D)</p> Signup and view all the answers

Which vitamin can interfere with blood-thinning medications if taken in excessive amounts?

<p>Vitamin E (B)</p> Signup and view all the answers

Which of the following micronutrients is synthesized in the skin upon exposure to sunlight?

<p>Vitamin D (C)</p> Signup and view all the answers

Beriberi, characterized by muscle weakness and nerve damage, is a deficiency syndrome associated with which vitamin?

<p>Vitamin B1 (Thiamin) (A)</p> Signup and view all the answers

A diet heavily reliant on corn is most likely to lead to a deficiency in which of the following vitamins?

<p>Vitamin B3 (Niacin) (A)</p> Signup and view all the answers

Flashcards

Vitamin A Functions

Vision, cell growth, immune function, and antioxidant activity.

Vitamin A Deficiency

Night blindness and Xerophthalmia.

Vitamin D Functions

Calcium absorption, bone health, immune support.

Vitamin D Deficiency

Rickets (children), Osteomalacia (adults).

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Vitamin E Functions

Protects cells from oxidative stress.

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Vitamin E Deficiency

Hemolytic anemia, neuromuscular dysfunction.

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Vitamin K Function

Activates blood clotting factors.

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Vitamin K Deficiency

Increased bleeding time.

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Vitamin C Functions

Collagen synthesis, antioxidant, enhances iron absorption.

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Vitamin C Deficiency

Bleeding gums, poor wound healing (Scurvy).

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Vitamin B1 (Thiamin) Function

Energy metabolism, nerve function.

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Vitamin B1 (Thiamin) Deficiency

Beriberi (muscle weakness, nerve damage).

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Iron Functions

Oxygen transport, enzyme function.

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Iron Deficiency

Iron-deficiency anemia (fatigue, weakness).

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Calcium Functions

Bone health, muscle contraction, nerve function.

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Study Notes

  • Topic is Micronutrients
  • Key vitamins and minerals are essential for various bodily functions

Fat-Soluble Vitamins (A, D, E, K)

Vitamin A

  • Functions include vision, cell growth and differentiation, immune function, and antioxidant properties.
  • Retinal is a component of rhodopsin in the retina.
  • Important, especially in skin and mucous membranes.
  • Supports white blood cell production.
  • Animal sources include liver, dairy, eggs, and fish.
  • Plant sources include carrots, sweet potatoes, and spinach, containing beta-carotene.
  • Night blindness is an early symptom of deficiency.
  • Xerophthalmia is a severe deficiency that can lead to blindness.
  • Toxicity can cause liver damage, birth defects, nausea, and dizziness.
  • Infants, pregnant women, and people with fat malabsorption disorders are at risk of deficiency.
  • Absorption is enhanced by dietary fat and bile salts.
  • Absorption is inhibited by excessive alcohol and a low-fat diet.

Vitamin D

  • Functions include calcium absorption, bone health, immune system support, muscle function, and cardiovascular health.
  • Animal sources include fatty fish (salmon, tuna), egg yolks, and fortified dairy products.
  • Synthesized in skin when exposed to sunlight.
  • Rickets (soft bones) occurs in children with deficiency.
  • Osteomalacia (weak bones) occurs in adults with deficiency.
  • Toxicity leads to hypercalcemia (excess calcium in blood) and kidney damage.
  • The elderly, people with limited sun exposure, and those with darker skin are at risk.
  • Absorption is enhanced by the presence of dietary fat and adequate sun exposure.
  • Absorption is inhibited by lack of sunlight and low dietary fat intake.

Vitamin E

  • Functions as an antioxidant, protecting cells from oxidative stress.
  • Maintains membrane integrity, especially in red blood cells, and supports immune function.
  • Sources include vegetable oils (sunflower, safflower), nuts (almonds, hazelnuts), and seeds.
  • Deficiency can result in hemolytic anemia due to red blood cell breakdown and neuromuscular dysfunction.
  • Toxicity can increase the risk of bleeding and impair blood clotting.
  • Premature infants and individuals with fat malabsorption disorders are at risk.
  • Absorption is enhanced by dietary fat.
  • Absorption is inhibited by high heat and food processing.

Vitamin K

  • Functions include blood clotting by activating clotting factors and bone mineralization involved in osteocalcin activation.
  • Sources include leafy green vegetables (spinach, kale, broccoli) and some synthesis by gut bacteria.
  • Deficiency leads to increased bleeding time.
  • Toxicity is rare but can interfere with blood-thinning medications.
  • Newborns receive a Vitamin K injection at birth, and people on long-term antibiotics are at risk.
  • Absorption is enhanced by dietary fat.
  • Absorption is inhibited by excessive vitamin E intake.

Water-Soluble Vitamins

Vitamin C

  • Functions: collagen synthesis for skin, blood vessels, and wound healing, antioxidant properties, and enhances iron absorption (especially non-heme iron).
  • Sources: citrus fruits, strawberries, bell peppers, and tomatoes.
  • Deficiency: results in scurvy (bleeding gums, poor wound healing).
  • People at Risk: smokers and individuals with poor fruit/vegetable intake.
  • Enhanced by: presence of iron
  • Inhibited by: heat and prolonged storage.

Vitamin B Group

Vitamin Functions Food Sources Deficiency Symptoms People at Risk
B1 (Thiamin) Energy metabolism, nerve function Whole grains, pork, legumes Beriberi (muscle weakness, nerve damage) Alcoholics, malnourished individuals
B2 (Riboflavin) Energy production, skin and eye health Dairy, eggs, leafy greens Cracks at mouth corners, inflamed tongue Individuals with poor dairy intake
B3 (Niacin) Energy metabolism, skin and digestive health Meat, fish, whole grains Pellagra (diarrhea, dermatitis, dementia) Populations with diets reliant on corn
B6 (Pyridoxine) Amino acid metabolism, neurotransmitter synthesis Poultry, bananas, potatoes Depression, confusion Alcoholics, individuals on certain medications
B9 (Folate) DNA synthesis, prevents neural tube defects Leafy greens, legumes, fortified grains Megaloblastic anemia, neural tube defects Pregnant women, alcoholics
B12 (Cobalamin) Red blood cell formation, nerve function Meat, dairy, eggs, fortified cereals Pernicious anemia, nerve damage Vegetarians, elderly with reduced stomach acid

Key Minerals

Mineral Functions Food Sources Deficiency Symptoms People at Risk
Iron Oxygen transport, enzyme function Red meat, poultry, fish (heme); Beans, spinach, fortified cereals (non-heme) Iron-deficiency anemia (fatigue, weakness) Women with heavy periods, vegetarians
Calcium Bone health, muscle contraction, nerve function Dairy, leafy greens, fortified foods Osteoporosis (weak bones, fractures) Postmenopausal women, lactose-intolerant individuals
Magnesium Muscle and nerve function, enzyme cofactor, bone health Nuts, seeds, whole grains, leafy greens Muscle cramps, irregular heartbeat Alcoholics, chronically ill individuals
Sodium Fluid balance, nerve Salt, processed foods, soy Hyponatremia (weakness, confusion) Endurance athletes, people with excessive sweating
Potassium Muscle contraction, nerve function, blood pressure regulation Bananas, potatoes, beans, dairy Muscle Weakness, irregular heartbeat Individuals on diuretics, high sodium intake

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