Microbiology Quiz: Neisseria Species
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Questions and Answers

Which species of Neisseria is linked to meningitis?

  • Neisseria meningitidis (correct)
  • Neisseria gonorrhoeae
  • Neisseria lactamica
  • Neisseria sicca
  • What type of organism is Neisseria gonorrhoeae?

  • Gram-positive coccus
  • Gram-positive bacillus
  • Gram-negative spirillum
  • Gram-negative cocci (correct)
  • How is Neisseria gonorrhoeae primarily transmitted?

  • Airborne droplets
  • Sexual contact (correct)
  • Insect bites
  • Contaminated food
  • Which of the following best describes the morphology of Neisseria species?

    <p>Non-motile diplococci</p> Signup and view all the answers

    What condition is primarily caused by Neisseria gonorrhoeae?

    <p>Gonorrhea</p> Signup and view all the answers

    What is the common appearance of Neisseria species under the microscope?

    <p>Diplococci</p> Signup and view all the answers

    What type of bacteria is Neisseria classified as?

    <p>Aerobic</p> Signup and view all the answers

    Which of the following is a common characteristic of Neisseria gonorrhoeae in clinical samples?

    <p>Presence in polymorphonuclear leukocytes</p> Signup and view all the answers

    What is the primary reason why the organism cannot survive long outside the human body?

    <p>It is highly sensitive to dehydration.</p> Signup and view all the answers

    Which symptom is most commonly associated with a gonococcal infection in females?

    <p>Greenish-yellow cervical discharge.</p> Signup and view all the answers

    What complication is associated with untreated gonococcal salpingitis in women?

    <p>Infertility due to tubal scarring.</p> Signup and view all the answers

    Ophthalmia neonatorum can be treated effectively with which antibiotic?

    <p>Erythromycin.</p> Signup and view all the answers

    Which of the following describes a potential outcome of infection with N. meningitidis?

    <p>Fulminant meningococcemia without meningitis.</p> Signup and view all the answers

    What population is at higher risk for outbreaks of meningitis caused by N. meningitidis?

    <p>People in crowded environments like schools and military barracks.</p> Signup and view all the answers

    Which of the following conditions may follow acute conjunctivitis if left untreated?

    <p>Permanent blindness.</p> Signup and view all the answers

    Which symptom is associated with both males and females suffering from gonococcal infections?

    <p>Pain during urination.</p> Signup and view all the answers

    What is the most important virulence factor of N.meningitidis?

    <p>Polysaccharide capsule</p> Signup and view all the answers

    Which group does the conjugate meningococcal vaccine (MCV4) target?

    <p>Adolescents and adults aged 11 to 55 years</p> Signup and view all the answers

    What symptoms are characteristic of meningitis caused by N.meningitidis?

    <p>Severe headache and rigid neck</p> Signup and view all the answers

    N.meningitidis initially colonizes which part of the body?

    <p>Nasopharynx</p> Signup and view all the answers

    What type of vaccine is Bexsero®?

    <p>Serogroup B meningococcal vaccine</p> Signup and view all the answers

    What can occur within several hours after the onset of symptoms in a meningococcal infection?

    <p>Coma</p> Signup and view all the answers

    Which of the following is NOT a serogroup included in the MCV4 vaccine?

    <p>Serogroup B</p> Signup and view all the answers

    Acute, fulminating meningococcal septicemia occurs mainly in which population?

    <p>Very young children</p> Signup and view all the answers

    Which genera are primarily associated with gastrointestinal diseases?

    <p>Escherichia</p> Signup and view all the answers

    What characteristic do members of the genus Acinetobacter possess?

    <p>Nonmotile coccobacilli</p> Signup and view all the answers

    What is the role of fimbriae or pili in E. coli?

    <p>Adherence to mucosal surfaces</p> Signup and view all the answers

    Which of the following pathogens is described as an opportunistic pathogen?

    <p>E. coli</p> Signup and view all the answers

    What distinguishes the transmission of organisms causing GI diseases?

    <p>Fecal contamination</p> Signup and view all the answers

    Which organisms primarily cause extraintestinal diseases?

    <p>Klebsiella and Proteus</p> Signup and view all the answers

    What type of bacteria are found in the gastrointestinal tract of humans or animals?

    <p>Facultative anaerobes</p> Signup and view all the answers

    Which statement about lipopolysaccharide (LPS) is true?

    <p>It acts as an endotoxin</p> Signup and view all the answers

    What is a major cause of neonatal meningitis within the first month of life?

    <p>E.coli</p> Signup and view all the answers

    What condition is primarily caused by serotype Typhi of Salmonella?

    <p>Typhoid fever</p> Signup and view all the answers

    Which symptom is NOT commonly associated with salmonella gastroenteritis?

    <p>Constipation</p> Signup and view all the answers

    Which species is known for causing shigellosis?

    <p>Shigella</p> Signup and view all the answers

    What is a common non-specific symptom associated with enteric (typhoid) fever?

    <p>Chills</p> Signup and view all the answers

    What can Campylobacter infections lead to in otherwise healthy individuals?

    <p>Acute enteritis</p> Signup and view all the answers

    What characteristic does the Shiga toxin possess?

    <p>Both enterotoxic and cytotoxic properties</p> Signup and view all the answers

    What type of lesions can Campylobacter cause in the intestines?

    <p>Ulcerative, inflammatory lesions</p> Signup and view all the answers

    Which type of E.coli is primarily associated with traveler's diarrhea?

    <p>Enterotoxigenic E.coli (ETEC)</p> Signup and view all the answers

    What primarily differentiates Enterohemorrhagic E.coli (EHEC) from other types of E.coli?

    <p>Produces an exotoxin causing bloody diarrhea</p> Signup and view all the answers

    Which strain of E.coli is most commonly associated with severe complications such as hemolytic uremic syndrome (HUS)?

    <p>O157:H7</p> Signup and view all the answers

    In which population is Enteropathogenic E.coli (EPEC) particularly significant as a cause of diarrhea?

    <p>Infants in areas with poor sanitation</p> Signup and view all the answers

    What type of disease is Enteroinvasive E.coli (EIEC) known to cause?

    <p>Dysentery-like syndrome</p> Signup and view all the answers

    What is the most common source of extraintestinal E.coli infections?

    <p>Patient's own nonpathogenic flora</p> Signup and view all the answers

    Which E.coli type causes persistent diarrhea in young children?

    <p>Enteroadherent E.coli (EAEC)</p> Signup and view all the answers

    Why are women particularly at risk for urinary tract infections (UTIs) caused by E.coli?

    <p>Shorter urethra</p> Signup and view all the answers

    Study Notes

    Gram-Negative Bacteria

    • Gram-negative bacteria are a diverse group of organisms, common in the gastrointestinal tract of animals, and sometimes pathogenic in humans.
    • Many gram-negative bacteria are aerobic, some are facultative anaerobes.
    • Important genera include: Neisseria, Moraxella, Haemophilus, Bordetella, Brucella, Enteric bacteria (e.g., Escherichia, Salmonella, Shigella, etc.), Campylobacter, Vibrio, Helicobacter, Legionella, Pseudomonas, Acinetobacter, Bacteroides, and Francisella.
    • These bacteria can be categorized as cocci, coccobacilli, or rods (bacilli - both straight and curved).
    • Various gram-negative bacteria cause diseases of the respiratory, gastrointestinal, genitourinary and other systems and can potentially cause a life-threatening condition.
    • Some are important nosocomial (hospital-acquired) pathogens.

    Gram-Negative Cocci

    • Members of Neisseria are nonmotile, gram-negative cocci, often found in pairs (diplococci)
    • Neisseria gonorrhoeae (gonococcus): sexually transmitted, causes gonorrhea
    • Neisseria meningitidis (meningococcus): causes meningitis
    • Both are nonmotile diplococci, and indistinguishable microscopically

    Gram-Negative Rods (Bacilli)

    • Key rod-shaped gram-negative bacteria categorized in different types based on their characteristics:
    • Respiratory organisms: Haemophilus, Bordetella, Legionella
    • Zoonotic organisms: Brucella, Francisella, Pasteurella, Yersinia
    • Enteric and related organisms: Escherichia, Enterobacter, Serratia, Salmonella etc.
    • Curved rods (also called Vibrios): Vibrio

    Other Gram-Negative Bacteria

    • Campylobacter: curved bacteria, cause enteritis
    • Shigella: causes shigellosis, usually among young children.
    • Helicobacter pylori: causes acute gastritis as well as duodenal and gastric ulcers.

    Specific Diseases

    • Ophthalmia neonatorum: conjunctival sac infection acquired from the mother during birth canal passage; can lead to blindness
    • Meningitis: inflammation of meninges; Neisseria meningitidis is a frequent cause, often resulting in a sudden onset and potentially life-threatening
    • Septicemia: presence of pathogenic microorganisms in the blood, often causing fatal consequences, caused by Neisseria meningitidis.
    • Urinary tract infection (UTI): E. coli is a leading cause of UTIs, including cystitis and pyelonephritis.
    • Gastroenteritis (intestinal infections): different types of E. coli cause different forms of diarrhea, both in the gastrointestinal tract and outside of it.

    Vaccination

    • Meningococcal conjugate vaccine (MCV4) and serogroup B meningococcal vaccines are available to prevent the disease.

    Treatment and Clinical Significance

    • Specific antibiotics are used to treat gram-negative bacterial infections, depending on the specific organism involved.
    • Many gram-negative bacteria cause life-threatening disease.
    • Treatment is frequently important and crucial to treat patients with diseases caused by gram-negative bacteria.

    Important Note: This information is for study purposes only. Consult healthcare professionals for accurate and timely medical advice. Always follow professional medical guidelines.

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    Description

    Test your knowledge on Neisseria species, including Neisseria gonorrhoeae and its relation to meningitis. This quiz covers their transmission, morphology, and clinical characteristics crucial for understanding microbiology. Challenge yourself with these key concepts!

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