Microbiology Quiz: Mycosis and Fungal Biology
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Questions and Answers

Which of the following is not a type of mycosis?

  • Systemic mycosis
  • Subcutaneous mycosis
  • Cutaneous mycosis
  • Infectious mycosis (correct)
  • Which of the following is a common example of a cutaneous mycosis?

  • Yeast infection
  • Ringworm (correct)
  • Athlete's foot (correct)
  • Pneumonia
  • What is the term for the microbes that typically cause cutaneous mycosis?

  • Protozoa
  • Viruses
  • Dermatophytes (correct)
  • Bacteria
  • Which type of mycosis involves the spread of fungal infection throughout the body?

    <p>Systemic mycosis (A)</p> Signup and view all the answers

    Which of the following is a common characteristic of opportunistic mycosis?

    <p>Occurs only in individuals with weakened immune systems (C)</p> Signup and view all the answers

    What enzyme do viruses need for reverse transcription?

    <p>Reverse transcriptase (D)</p> Signup and view all the answers

    What is the name of the integrated viral DNA within the host cell's genome?

    <p>Provirus (A)</p> Signup and view all the answers

    Which of the following enzymes is responsible for integrating viral DNA into the host cell's genome?

    <p>Integrase (A)</p> Signup and view all the answers

    What triggers the activation of the viral DNA genes?

    <p>Stress or illness (B)</p> Signup and view all the answers

    What is the final product of viral DNA transcription?

    <p>mRNA (A)</p> Signup and view all the answers

    What is the main role of fungi in the ecosystem?

    <p>To break down organic matter and recycle nutrients (D)</p> Signup and view all the answers

    Which of the following is NOT a defining characteristic of fungi?

    <p>They are prokaryotic organisms (C)</p> Signup and view all the answers

    What is the name of the network of filaments that make up a multicellular fungus?

    <p>Mycelium (D)</p> Signup and view all the answers

    Which of the following is an example of asexual reproduction in fungi?

    <p>All of the above (D)</p> Signup and view all the answers

    What is the name of the fungal cell wall component that is unique to fungi?

    <p>Chitin (D)</p> Signup and view all the answers

    What is the name of the sterol found specifically in fungal cell membranes?

    <p>Ergosterol (D)</p> Signup and view all the answers

    Which of the following is a characteristic of fungal infections compared to bacterial infections?

    <p>Fungal infections tend to grow more slowly than bacterial infections (A)</p> Signup and view all the answers

    What type of mycosis affects the epidermis, hair, and nails without digesting keratin?

    <p>Superficial mycosis (A)</p> Signup and view all the answers

    Which of the following can promote the transmission of fungal pathogens?

    <p>Moist environments (A)</p> Signup and view all the answers

    What is the term for a disease caused by a fungus?

    <p>Mycosis (C)</p> Signup and view all the answers

    What is the name of the protein coat that surrounds the nucleic acid of a virion?

    <p>Capsid (C)</p> Signup and view all the answers

    Which of the following is a characteristic of a non-enveloped virus?

    <p>It does not have a phospholipid layer surrounding the capsid (A)</p> Signup and view all the answers

    What is the function of the tail fibers in bacteriophages?

    <p>To attach the bacteriophage to the host cell (C)</p> Signup and view all the answers

    Which of the following is a type of capsid shape?

    <p>Icosahedral (D)</p> Signup and view all the answers

    What is the function of the spikes in enveloped viruses?

    <p>To attach the virus to the host cell (B)</p> Signup and view all the answers

    What type of nucleic acid is present in the virion?

    <p>Either DNA or RNA (C)</p> Signup and view all the answers

    What is the function of the capsomere in a virion?

    <p>To protect the nucleic acid from damage (B)</p> Signup and view all the answers

    What is the difference between a virion and a bacteriophage?

    <p>Bacteriophages have a more complex structure than virions (C)</p> Signup and view all the answers

    What is the name of the enzyme responsible for synthesizing viral DNA from RNA?

    <p>Reverse transcriptase (B)</p> Signup and view all the answers

    What is the function of integrase in viral replication?

    <p>It integrates viral DNA into host DNA. (A)</p> Signup and view all the answers

    What is the name of the process by which enveloped viruses exit the host cell?

    <p>Both B and C (C)</p> Signup and view all the answers

    What is the name of the structure that protects the viral genome?

    <p>Capsid (C)</p> Signup and view all the answers

    What is the name of the process by which a virus inserts its genetic material into a host cell?

    <p>Entry (B)</p> Signup and view all the answers

    During the biosynthesis stage of viral replication, what is the role of the viral RdRp (RNA-dependent RNA Polymerase)?

    <p>It replicates viral RNA. (A)</p> Signup and view all the answers

    What is the name of the DNA molecule that results from the integration of viral DNA into the host cell's genome?

    <p>Provirus (B)</p> Signup and view all the answers

    What is the nature of prions?

    <p>Prions are small, non-cellular infectious agents that contain only protein. (C)</p> Signup and view all the answers

    How can prions cause disease?

    <p>Prions induce the misfolding of normal proteins in the brain, leading to neurodegenerative diseases. (A)</p> Signup and view all the answers

    Which of the following is a characteristic of prion diseases?

    <p>Prion diseases are slow-progressing and often fatal. (C)</p> Signup and view all the answers

    What is the most common route of transmission for prion diseases?

    <p>Prion diseases are often transmitted through contaminated medical instruments or tissues. (B)</p> Signup and view all the answers

    Which of the following diseases are caused by prions?

    <p>Creutzfeldt-Jakob disease and Mad Cow disease. (C)</p> Signup and view all the answers

    How can cats become re-infected with a parasite?

    <p>By consuming contaminated food or water (C), By consuming infected intermediate hosts like birds or rodents (D)</p> Signup and view all the answers

    Which of the following is NOT a method of transmission for the parasite?

    <p>Direct contact with infected animals (B)</p> Signup and view all the answers

    What is the role of birds and rodents in the parasite's life cycle?

    <p>They are intermediate hosts, harboring the parasite's larval stages (A)</p> Signup and view all the answers

    What is the most likely way a pregnant cat can pass the infection to her fetus?

    <p>Through the placenta (B)</p> Signup and view all the answers

    What is the primary way the parasite spreads through the environment?

    <p>Through contaminated water (B)</p> Signup and view all the answers

    What is the name of the disease caused by Entamoeba histolytica?

    <p>Amoebiasis (B)</p> Signup and view all the answers

    How is the transmission of amoebic cysts primarily facilitated?

    <p>Contaminated food or water ingestion (A)</p> Signup and view all the answers

    What is a potential complication of amoebiasis?

    <p>Formation of cysts that spread to other organs (C)</p> Signup and view all the answers

    Which mosquito genus is recognized as the definitive host for the organism responsible for malaria?

    <p>Anopheles (A)</p> Signup and view all the answers

    Which of the following symptoms is associated with amoebiasis?

    <p>Diarrhea with mucus (B)</p> Signup and view all the answers

    What substance does a mosquito inject into a human when it bites?

    <p>Gametes (D)</p> Signup and view all the answers

    What is the intermediate host in the life cycle of Plasmodium?

    <p>Human (D)</p> Signup and view all the answers

    What is the name of the stage where sporozoites undergo division to form merozoites?

    <p>Schizogony (A)</p> Signup and view all the answers

    What do trophozoites eventually form after infecting red blood cells?

    <p>More merozoites (B)</p> Signup and view all the answers

    What is a key symptom of the infection caused by Plasmodium?

    <p>Extreme fever and chills (A)</p> Signup and view all the answers

    Which organism is the definitive host for Toxoplasmosis gondii?

    <p>Cat (B)</p> Signup and view all the answers

    What do merozoites infect in humans to cause disease?

    <p>Red blood cells (B)</p> Signup and view all the answers

    What are the toxins released from lysed RBCs mainly responsible for?

    <p>Causing symptoms (B)</p> Signup and view all the answers

    What is a primary method of transmission for prion diseases?

    <p>Consumption of contaminated food (B)</p> Signup and view all the answers

    Which of the following best describes how prions cause disease?

    <p>By forming abnormal proteins that induce misfolding of normal proteins (C)</p> Signup and view all the answers

    Which of the following diseases is an example of a prion disease?

    <p>Mad cow disease (D)</p> Signup and view all the answers

    What is the structural nature of prions?

    <p>Misfolded proteins lacking nucleic acids (B)</p> Signup and view all the answers

    Which characteristic distinguishes prions from other infectious agents?

    <p>Lack of nucleic acids (D)</p> Signup and view all the answers

    What type of nucleic acid can be found in a virion?

    <p>DNA or RNA (A)</p> Signup and view all the answers

    Which term describes the protein coat surrounding the nucleic acid in a virion?

    <p>Capsid (C)</p> Signup and view all the answers

    What shape is a virus with an icosahedral capsid?

    <p>Polygon with 20 sides (C)</p> Signup and view all the answers

    What feature do enveloped viruses possess that non-enveloped viruses do not?

    <p>Phospholipid layer (A)</p> Signup and view all the answers

    What structure of a bacteriophage is primarily responsible for attachment to the host cell?

    <p>Tail fibers (A)</p> Signup and view all the answers

    What is the term for viruses that lack an envelope?

    <p>Naked viruses (A)</p> Signup and view all the answers

    Which type of genome do bacteriophages predominantly have?

    <p>DNA (D)</p> Signup and view all the answers

    What are the smaller subunits that make up the capsid called?

    <p>Capsomeres (B)</p> Signup and view all the answers

    What characterizes an acute viral infection?

    <p>The virus reproduces rapidly and causes symptoms over a brief period. (D)</p> Signup and view all the answers

    What type of viral infection involves the immune system's inactivation?

    <p>Chronic viral infection (D)</p> Signup and view all the answers

    How can some viruses contribute to cancer development?

    <p>By transforming normal cells into malignant cells. (C)</p> Signup and view all the answers

    What are prions primarily composed of?

    <p>Misfolded proteins (D)</p> Signup and view all the answers

    What is one method by which prions can spread from animals to humans?

    <p>Ingesting contaminated meat (D)</p> Signup and view all the answers

    What occurs when a prion comes into contact with a normal protein?

    <p>The normal protein misfolds, losing its function. (A)</p> Signup and view all the answers

    Which of the following diseases is an example of a chronic viral infection?

    <p>Hepatitis C (A)</p> Signup and view all the answers

    Which of the following best defines a latent viral infection?

    <p>The virus remains inactive within the host cell. (A)</p> Signup and view all the answers

    What key characteristic defines cancer cells?

    <p>They grow uncontrollably. (A)</p> Signup and view all the answers

    What is the primary route of transmission for inherited prion diseases?

    <p>Inherited genetic mutations (A)</p> Signup and view all the answers

    Flashcards

    Cutaneous Mycosis

    A fungal infection affecting the epidermis, hair, and nails, caused by dermatophytes.

    Dermatophytes

    Microbes that cause cutaneous mycosis by digesting keratin.

    Subcutaneous Mycosis

    A fungal infection that penetrates deeper tissues beyond the dermis.

    Systemic Mycosis

    A fungal infection that spreads throughout the body, often from the respiratory system.

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    Opportunistic Mycosis

    Fungal infections occurring in immunocompromised patients, like yeast infections.

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    Role of Fungi

    Fungi mainly act as decomposers and are used in food production.

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    Reverse transcriptase

    An enzyme required by retroviruses to convert RNA into DNA.

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    Fungal Cell Membrane Component

    Fungal cell membranes contain ergosterol.

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    Integrase

    An enzyme that integrates viral DNA into the host's DNA, forming a provirus.

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    Fungal Cell Wall Component

    Fungal cell walls contain chitin.

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    Provirus

    Viral DNA that is integrated into the host DNA permanently.

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    Multicellular Fungi

    Multicellular fungi are known as molds, consisting of filaments called hyphae.

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    Trigger for activation

    A specific event that activates proviral genes; often linked to illness.

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    Unicellular Fungi

    Unicellular fungi are referred to as yeasts.

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    Viral biosynthesis

    The process through which viruses are produced after their activation.

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    Fungi Sexual Reproduction

    Fungi reproduce sexually by producing gametes.

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    Asexual Reproduction in Fungi

    Fungi reproduce asexually through mitosis, budding, fragmentation, or spores.

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    Mycosis

    A disease caused by fungi is called mycosis.

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    Skin Infection Pathway

    Fungus-causing skin infections can enter through wounds or be part of resident microbiota.

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    Superficial Mycosis

    A superficial mycosis is a fungal infection of the epidermis, hair, and nails without keratin digestion.

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    Diseases caused by prions

    Two examples are Creutzfeldt-Jakob disease and Mad Cow disease.

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    Structure of platyhelminths

    Platyhelminths have a flat body, no body cavity, and a mouth but no anus.

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    Schistosoma transmission

    Schistosoma is transmitted through water contaminated with larvae from infected snails.

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    Types of persistent viral infections

    Two types are latent infections and chronic infections.

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    Differences between an animal virus and bacteriophage

    Animal viruses infect animal cells, while bacteriophages infect bacteria.

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    Virion

    A complete virus particle that can infect eukaryote cells.

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    Nucleic Acid

    The genetic material of a virus, which can be DNA or RNA.

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    Capsid

    A protein coat that surrounds and protects the viral nucleic acid.

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    Capsomere

    The smaller protein subunits that make up the capsid.

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    Helical Capsid

    A capsid shape that is spiral or rod-like in form.

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    Icosaheral Capsid

    A virus shape with 20 triangular faces (polygons).

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    Enveloped Virus

    A virus that has a lipid layer surrounding its capsid.

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    Bacteriophage

    A virus that specifically infects bacteria.

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    Viral Entry

    The process where a virus attaches to and enters a host cell.

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    Viral Assembly

    The spontaneous process where viral capsid and genome come together.

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    Viral Release

    The method by which a virus exits a host cell.

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    Budding

    A viral exit method where the virus acquires an envelope from the host's membrane.

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    Cell Lysis

    A process where non-enveloped viruses burst the host cell to escape.

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    RNA-dependent RNA polymerase (RdRp)

    An enzyme that synthesizes RNA from an RNA template during viral biosynthesis.

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    Fusion (in viral entry)

    The process by which a virus merges with the host cell membrane to enter the cell.

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    Re-infection in Cats

    Cats can be re-infected by consuming infected intermediate hosts or feces.

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    Fecal-oral route

    The fecal-oral route is how infections spread through contaminated food or water.

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    Intermediate hosts

    Animals that can carry and pass infections to cats, like birds and rodents.

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    Transmission through placenta

    Pregnant animals can pass infections from themselves to the fetus via the placenta.

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    Cysts in food

    Cysts can be transferred by consuming the meat of infected animals.

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    Amoebiasis

    A disease caused by Entamoeba histolytica, leading to dysentery.

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    Transmission of amoebic cysts

    Amoebic cysts are passed through fecal-oral route via contaminated food/water.

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    Symptoms of amoebiasis

    Main symptoms include diarrhea, mucus, pain, and flatulence.

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    Complications of amoebiasis

    Can include cyst formation and chronic infection, affecting other organs.

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    Plasmodium spp. and malaria

    Plasmodium species are responsible for causing malaria, transmitted by Anopheles mosquitoes.

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    Plasmodium

    A genus of parasites that cause malaria and require mosquitoes to complete their lifecycle.

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    Sporozoites

    The infectious form of Plasmodium that enters the human bloodstream through mosquito bites.

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    Merozoites

    The form of Plasmodium that infects red blood cells, produced from sporozoites.

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    Trophozoites

    The stage of Plasmodium where merozoites grow and then lyse red blood cells.

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    Lyse

    To break down or burst; in malaria, it refers to red blood cells being destroyed by trophozoites.

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    Toxoplasmosis gondii

    A parasite that causes toxoplasmosis, often associated with cats as the definitive host.

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    Key symptoms of malaria

    Extreme fever, chills, and anemia due to red blood cell destruction.

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    Virion Structure

    The general arrangement of viral components including nucleic acid, capsid, and sometimes envelope.

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    Bacteriophage Structure

    The structure of a bacteriophage, which includes a polyhedral capside, sheath, and tail fibers.

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    Tail Fibres

    Structures attached to the sheath of a bacteriophage, involved in attachment to host bacteria.

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    Non-Enveloped Virus

    A virus that lacks an envelope and is more resistant to environmental conditions.

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    Acute Viral Infection

    A viral infection where the virus rapidly reproduces, causing symptoms over a brief period.

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    Examples of Acute Viral Infection

    Common viral infections like the cold and influenza.

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    Persistent Viral Infection

    A viral infection where the virus cannot be cleared from the body.

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    Latent Viral Infection

    A persistent infection where the virus becomes dormant in the host cell.

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    Example of Latent Infection

    Herpes simplex virus, which can remain dormant in nerve cells.

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    Chronic Viral Infection

    A persistent infection where symptoms are recurrent and the virus evades the immune system.

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    How Viruses Cause Cancer

    Viruses can transform normal cells into malignant cells by inserting their genome.

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    How Prions Spread

    Prions transmit disease through ingestion of contaminated meat or contact with infected tissues.

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    Transmission of Schistosoma

    Schistosoma is transmitted through water contaminated with larvae from infected snails.

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    Types of platyhelminths

    The two types are cestodes (tapeworms) and trematodes (flukes).

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    Life cycle of non-enveloped RNA viruses

    Non-enveloped RNA viruses enter host cells, replicate, and are released without a lipid envelope.

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    Study Notes

    Eukaryotic Pathogens (Fungi)

    • Fungi are decomposers, playing a key role in breaking down structural components.
    • Fungal cell membranes contain ergosterol, and cell walls contain chitin.
    • Fungi exist in two main forms: multicellular molds (hyphae, mycelium) and unicellular yeasts.
    • Fungi reproduce sexually (through gametes) and asexually (by mitosis, budding, fragmentation, spores).

    Mycoses (Fungal Infections)

    • A mycosis is a disease caused by a fungus.
    • Fungal infections grow more slowly than bacterial infections.
    • Transmission of fungal infections can be aided by moist environments.
    • Five types of mycoses: superficial, cutaneous, subcutaneous, systemic, and opportunistic.
      • Superficial mycoses affect the epidermis, hair, and nails, without keratin degradation.
      • Cutaneous mycoses affect the epidermis, hair, and nails, with keratin degradation (examples: ringworm, athlete's foot).
      • Subcutaneous mycoses affect deeper tissues below the dermis.
      • Systemic mycoses involve the entire body (e.g., from the respiratory system).
      • Opportunistic mycoses occur when the immune system is compromised (e.g., yeast infections).

    Eukaryotic Pathogens (Algae)

    • Algae are photoautotrophs (capable of photosynthesis).
    • Algae contain pigments that give them different colors.
    • Multicellular algae are known as seaweeds.
    • Some unicellular algae produce toxins, and blooms can lead to high toxin concentrations.
    • Examples of diseases caused by unicellular algae include Diatomaceous earth poisoning (domoic acid toxicosis) and Paralytic Shellfish Poisoning (PSP).

    Eukaryotic Pathogens (Protozoa)

    • Protozoa are diverse, living in various environments; some are free-living, while others are parasitic.
    • The trophozoite form is the active, growing phase in a host; a cyst is a dormant form.
    • Protozoa reproduce sexually (gametes) via asexual methods such as binary fission, budding, or schizogony.
    • Some species require multiple hosts in their life cycles; a definitive host is where sexual reproduction occurs, whereas intermediate hosts are where asexual reproduction occurs.
    • Examples of protozoan diseases include amoebiasis (Entamoeba histolytica), malaria (Plasmodium spp), and toxoplasmosis (Toxoplasma gondii).

    Eukaryotic Pathogens (Helminths)

    • Parasitic helminths rely on a host for survival, compared to their free-living counterparts.
    • Parasitic helminths have reduced digestive, nervous, temperature, and locomotor systems.
    • Two main types of helminths are platyhelminthes (flatworms), and nematodes (roundworms).
    • Examples of helminth diseases include schistomiasis caused by Schistosoma and taeniasis caused by Taenia solium.

    Viruses

    • Viruses are acellular, meaning they are not composed of cells.
    • Viruses are classified as obligate intracellular parasites since they need a host cell to replicate.
    • Viruses have a nucleic acid (DNA or RNA) core surrounded by a protein coat called a capsid.
      • Enveloped viruses have an outer layer of phospholipid.
      • Non-enveloped viruses do not have this outer layer.
    • Viruses can cause acute or persistent/chronic infections.
    • Viral infections can cause cancer.
    • Certain viruses, such as HIV, cause cancer.

    Prions

    • Prions are misfolded proteins that cause diseases like Creutzfeldt-Jakob disease (CJD) and bovine spongiform encephalopathy (BSE, or mad cow disease).
    • Prion replication occurs by contact with normal, correctly folded, proteins in a host.
    • Misfolded proteins cause neurological issues and neuronal death leading to the characteristic spongiform deterioration in the brain.

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    Description

    Test your knowledge on mycosis and the role of fungi in microbiology. This quiz covers various types of mycosis, their characteristics, and important concepts like viral DNA integration. Challenge yourself to see how much you know about this fascinating field of study!

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