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Questions and Answers
What is the typical molecular weight of cytokines?
What is the typical molecular weight of cytokines?
- 100KDa
- 50KDa
- 30KDa (correct)
- 10KDa
What is the primary function of cytokines in regulating immune effector cells?
What is the primary function of cytokines in regulating immune effector cells?
- To inhibit the inflammatory response
- To stimulate the development of immune effector cells (correct)
- To produce antibodies
- To induce apoptosis in infected cells
What is the characteristic of the binding between cytokines and their receptors?
What is the characteristic of the binding between cytokines and their receptors?
- Reversible reaction
- Specificity for multiple receptors
- Low affinity
- High affinity (correct)
What is an example of autocrine action of cytokines?
What is an example of autocrine action of cytokines?
What is one of the biological functions of cytokines?
What is one of the biological functions of cytokines?
What is the target of cytokine signal transduction pathway?
What is the target of cytokine signal transduction pathway?
At what concentration can cytokines mediate biological effects?
At what concentration can cytokines mediate biological effects?
What is a primary function of cytokines of the hematopoietin family?
What is a primary function of cytokines of the hematopoietin family?
What is the term for the soluble factor-directed cell movement induced by chemokines?
What is the term for the soluble factor-directed cell movement induced by chemokines?
Which of the following cytokines is involved in the differentiation of a T helper cell?
Which of the following cytokines is involved in the differentiation of a T helper cell?
What is the primary function of interferons?
What is the primary function of interferons?
What is the term for the small, soluble cytokines that communicate between and among cells of the immune system?
What is the term for the small, soluble cytokines that communicate between and among cells of the immune system?
Which of the following cytokines is involved in the differentiation of B-cells into plasma cells?
Which of the following cytokines is involved in the differentiation of B-cells into plasma cells?
What is the term for the molecules that can elicit the movement of leukocytes towards a chemokine source?
What is the term for the molecules that can elicit the movement of leukocytes towards a chemokine source?
What is the primary function of type I IFNs?
What is the primary function of type I IFNs?
Which type of IFN has only one representative?
Which type of IFN has only one representative?
What is the role of IFN-γ in immune responses?
What is the role of IFN-γ in immune responses?
What is the primary function of type III IFNs?
What is the primary function of type III IFNs?
During an infectious process, which type of IFN becomes abundant and is easily detectable in the blood?
During an infectious process, which type of IFN becomes abundant and is easily detectable in the blood?
What is the term derived from the ability of these cytokines to do?
What is the term derived from the ability of these cytokines to do?
What is the role of interleukins in the immune system?
What is the role of interleukins in the immune system?
Which cells are responsible for synthesizing interleukins?
Which cells are responsible for synthesizing interleukins?
What is the naming convention for interleukins?
What is the naming convention for interleukins?
How many members does the TNF family have?
How many members does the TNF family have?
Which cell type produces TNF-α primarily?
Which cell type produces TNF-α primarily?
What is the effect of TNF-α on neutrophils and endothelial cells?
What is the effect of TNF-α on neutrophils and endothelial cells?
What is the function of Fas ligand (FasL) in the TNF family?
What is the function of Fas ligand (FasL) in the TNF family?
What is the primary function of TNF-β?
What is the primary function of TNF-β?
Which cells can produce TNF-α in response to infection or inflammation?
Which cells can produce TNF-α in response to infection or inflammation?
What is the relationship between TNF-α and inflammation?
What is the relationship between TNF-α and inflammation?
Which cells are responsible for producing TNF-β?
Which cells are responsible for producing TNF-β?
What is the effect of TNF-α on neutrophils?
What is the effect of TNF-α on neutrophils?
Which cytokine is involved in inducing apoptosis?
Which cytokine is involved in inducing apoptosis?
What is the primary function of TNF-α in response to infection?
What is the primary function of TNF-α in response to infection?
Which cells are responsible for synthesizing interleukins, besides helper CD4+ T lymphocytes?
Which cells are responsible for synthesizing interleukins, besides helper CD4+ T lymphocytes?
What is the relationship between TNF-α and inflammation?
What is the relationship between TNF-α and inflammation?
What is the primary function of TNF-β?
What is the primary function of TNF-β?
Which cells are responsible for producing TNF-α, besides activated macrophages?
Which cells are responsible for producing TNF-α, besides activated macrophages?
What is the effect of TNF-α on endothelial cells?
What is the effect of TNF-α on endothelial cells?
Which cytokine family has Fas ligand (FasL) as a member?
Which cytokine family has Fas ligand (FasL) as a member?
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