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Microbial Chemotherapy Lecture Quiz

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12 Questions

Which component in penicillins is responsible for their activity?

Beta-lactam ring

What is the clinical spectrum of activity for amoxicillin?

Broad

Which route is commonly used for administering amoxicillin?

Oral

What is the primary pathway of elimination for amoxicillin?

Renal excretion

Which adverse reaction is commonly associated with penicillins?

Allergic reactions

What is the mechanism of action for aminoglycosides like gentamicin?

Inhibit protein synthesis

Which of the following antibiotics has a mechanism of action that involves irreversible inhibition of protein synthesis?

Streptomycin

Which antibiotic is most commonly associated with ototoxicity and nephrotoxicity?

Streptomycin

Which antibiotic has a high lipid solubility and is contraindicated in children and pregnancy?

Minocycline

Which of the following antibiotics is bactericidal and concentrates in renal cortical tissue?

Streptomycin

Which antibiotic can cause photosensitivity and accumulates well in body fluids and tissues?

Tetracycline

Which of the following antibiotics interferes with the release of acetylcholine (Ach) and may cause neuromuscular junction blockage?

Streptomycin

Test your knowledge on the pharmacology of amoxicillin, gentamicin, and tetracyclines including chemistry, mechanism of action, spectrum of activity, pharmacokinetics, and development of resistance. This quiz covers important points discussed during Prof. Maxine Gossell-Williams' lecture.

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