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Microbial Chemotherapy Lecture Quiz

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24 Questions

Amoxicillin is an example of a penicillin with a narrow spectrum of activity.

False

Penicillins inhibit the formation of the cell membrane of bacteria.

False

Amoxicillin is primarily excreted through the liver.

False

Aminoglycosides like gentamicin are non-polar compounds.

False

Gentamicin is commonly used to treat fungal infections.

False

Resistance to penicillins can occur due to the breaking of the amino sugar ring by bacteria.

False

Streptomycin irreversibly inhibits protein synthesis.

True

Streptomycin can easily pass through cell membranes due to its high polarity.

False

Nephrotoxicity caused by streptomycin is irreversible.

False

Minocycline exerts its action through irreversible inhibition of protein synthesis.

False

Tetracyclines, including minocycline, are not affected by food or metal ions during metabolism.

False

Minocycline is contraindicated in children and pregnant women.

True

Amoxicillin is derived from Penicillium chrysogenum.

True

Gentamicin is a non-polar compound.

False

Resistance to penicillins can occur due to the breaking of the beta-lactam ring by bacteria.

False

Minocycline's action is through irreversible inhibition of protein synthesis.

True

Amoxicillin has a broad spectrum of activity.

True

Streptomycin can easily pass through cell membranes due to its high polarity.

False

Streptomycin is absorbed when given parenterally due to its low polarity allowing for passage across membranes.

False

Minocycline exerts its bacteriostatic action through reversible inhibition of protein synthesis.

True

Streptomycin is primarily metabolized in the liver and eliminated unchanged through bile.

False

Tetracyclines, including minocycline, are affected by food and metal ions during absorption and distribution.

False

Photosensitivity is a common adverse effect associated with minocycline administration.

True

Nephrotoxicity caused by streptomycin is irreversible even after discontinuation of the drug.

False

Test your knowledge on the pharmacology of amoxicillin, gentamicin, and tetracyclines, covering topics such as chemistry, mechanism of action, spectrum of activity, pharmacokinetics, and development of resistance. This quiz is based on a lecture by Prof. Maxine Gossell-Williams from UWI's Pharmacology Section.

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