24 Questions
Amoxicillin is an example of a penicillin with a narrow spectrum of activity.
False
Penicillins inhibit the formation of the cell membrane of bacteria.
False
Amoxicillin is primarily excreted through the liver.
False
Aminoglycosides like gentamicin are non-polar compounds.
False
Gentamicin is commonly used to treat fungal infections.
False
Resistance to penicillins can occur due to the breaking of the amino sugar ring by bacteria.
False
Streptomycin irreversibly inhibits protein synthesis.
True
Streptomycin can easily pass through cell membranes due to its high polarity.
False
Nephrotoxicity caused by streptomycin is irreversible.
False
Minocycline exerts its action through irreversible inhibition of protein synthesis.
False
Tetracyclines, including minocycline, are not affected by food or metal ions during metabolism.
False
Minocycline is contraindicated in children and pregnant women.
True
Amoxicillin is derived from Penicillium chrysogenum.
True
Gentamicin is a non-polar compound.
False
Resistance to penicillins can occur due to the breaking of the beta-lactam ring by bacteria.
False
Minocycline's action is through irreversible inhibition of protein synthesis.
True
Amoxicillin has a broad spectrum of activity.
True
Streptomycin can easily pass through cell membranes due to its high polarity.
False
Streptomycin is absorbed when given parenterally due to its low polarity allowing for passage across membranes.
False
Minocycline exerts its bacteriostatic action through reversible inhibition of protein synthesis.
True
Streptomycin is primarily metabolized in the liver and eliminated unchanged through bile.
False
Tetracyclines, including minocycline, are affected by food and metal ions during absorption and distribution.
False
Photosensitivity is a common adverse effect associated with minocycline administration.
True
Nephrotoxicity caused by streptomycin is irreversible even after discontinuation of the drug.
False
Test your knowledge on the pharmacology of amoxicillin, gentamicin, and tetracyclines, covering topics such as chemistry, mechanism of action, spectrum of activity, pharmacokinetics, and development of resistance. This quiz is based on a lecture by Prof. Maxine Gossell-Williams from UWI's Pharmacology Section.
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