Chemotherapy and Microbial Identification Quiz
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Questions and Answers

Activities of a chemotherapeutic agent that damage the host are:

  • antimetabolites
  • broad spectrum
  • side effects (correct)
  • plasmids
  • An example of an antifungal agent is which of the following?

  • Keflex
  • griseofulvin (correct)
  • ampicillin
  • tetracycline
  • interferon
  • Which organism would not produce catalase?

  • Staphylococcus aureus
  • Bacillus subtilis
  • Pseudomonas aeruginosa
  • Bacteroides amylophilus (correct)
  • Name an organism that can convert H2SO4 to H2S?

    <p>Thiobacillus thiooxidans</p> Signup and view all the answers

    An example of an antimalarial drug is:

    <p>artemisinin</p> Signup and view all the answers

    Bacteria reproduce by the process called:

    <p>binary fission</p> Signup and view all the answers

    An example of an antiviral agent is:

    <p>amantadine</p> Signup and view all the answers

    An example of a macrolide antibiotic is:

    <p>erythromycin</p> Signup and view all the answers

    Name a toxic form of oxygen:

    <p>a and b</p> Signup and view all the answers

    When would you use the most probable number method?

    <p>When the organism cannot grow on agar</p> Signup and view all the answers

    The precursor of GMP and AMP is

    <p>IMP</p> Signup and view all the answers

    An example of an organism that could be found growing in jam is:

    <p>Xeromyces sp.</p> Signup and view all the answers

    Which of the following is not a form of ionizing radiation?

    <p>ultraviolet light</p> Signup and view all the answers

    A period of two hours at 160°C is required for killing bacteria:

    <p>in an autoclave</p> Signup and view all the answers

    Copper has its principal activity against:

    <p>pathogenic fungi</p> Signup and view all the answers

    Organisms that grow at low temperatures are called:

    <p>psychrophiles</p> Signup and view all the answers

    The two most important alcohol germicides are:

    <p>ethanol and isopropanol</p> Signup and view all the answers

    An inhibitor of nucleotide biosynthesis is:

    <p>aminopterin</p> Signup and view all the answers

    A sterilizer that employs superheated steam under pressure is called a(n)::

    <p>autoclave</p> Signup and view all the answers

    Which of the following is a sterilizing gas that can be used on hospital gowns and instruments?

    <p>ethylene oxide</p> Signup and view all the answers

    A pure culture:

    <p>has only one type of organism growing on it</p> Signup and view all the answers

    Coenzyme A plays an important role in the synthesis of:

    <p>lipids</p> Signup and view all the answers

    An example of a psychrophilic bacterium is:

    <p>Polaromonas vacuolata</p> Signup and view all the answers

    Removal of microorganisms from liquids and gases by passing them by passing the material through a substance with pore sizes designed not to allow microorganisms to penetrate is called:

    <p>filtration</p> Signup and view all the answers

    Beta-galactosidase converts lactose into:

    <p>glucose and galactose</p> Signup and view all the answers

    An organism that requires oxygen but at lower concentrations than those found in the atmosphere is called:

    <p>microaerophilic</p> Signup and view all the answers

    An instrument that uses high frequency ultrasonic waves to open cells is a:

    <p>cavitron</p> Signup and view all the answers

    NADP is reduced to NADPH in the:

    <p>pentose phosphate pathway</p> Signup and view all the answers

    Organisms that have a narrow range of growth temperatures are said to be:

    <p>stenothermal</p> Signup and view all the answers

    The product of gluconeogenesis is:

    <p>glucose-6-PO4</p> Signup and view all the answers

    The optimum temperature is usually closer to the minimum temperature than the maximum temperature.

    <p>False</p> Signup and view all the answers

    A nitrogenous base containing a double ring is a :

    <p>purine</p> Signup and view all the answers

    Sulfur is needed by all bacteria. Its main use is:

    <p>as a cell wall component</p> Signup and view all the answers

    The killing of vegetative forms of pathogenic microorganisms on inanimate objects is called:

    <p>disinfection</p> Signup and view all the answers

    The enzyme that breaks down starch is called:

    <p>amylase</p> Signup and view all the answers

    Organisms that require high salt concentrations to grow are called:

    <p>aerobic halophilic</p> Signup and view all the answers

    This is a reactive halogen element:

    <p>bromine</p> Signup and view all the answers

    A growth medium in which all the components and their specific concentrations are known is called a:

    <p>defined media</p> Signup and view all the answers

    Name a cellulase-producing organism:

    <p>Bacillus subtilis</p> Signup and view all the answers

    Name an organism that can convert fumarate to succinate using anaerobic respiration:

    <p>Methanococcus jannaschii</p> Signup and view all the answers

    You have just fertilized a field with nitrates. By the end of the year all the nitrates are gone. Name a microorganism that is capable of using these nitrates:

    <p>Pseudomonas denitrificans</p> Signup and view all the answers

    An organism that contains Beta-galactosidase is:

    <p>Escherichia coli</p> Signup and view all the answers

    The type of bacteria most likely to be found in the anaerobic digestor of a sewage treatment plant is:

    <p>Methanococcus jannaschii</p> Signup and view all the answers

    This antibiotic is active against rickettsias, chlamydias, and gram-negative bacteria:

    <p>tetracycline</p> Signup and view all the answers

    Organisms that ignore oxygen and grow equally well in its presence or absence are:

    <p>barotolerante aerotolerant anaerobe</p> Signup and view all the answers

    Cells may enter the stationary phase of growth because of:

    <p>all of the above</p> Signup and view all the answers

    You are working on a study of the viable cells in a bacterial suspension. You would count these cells using a:

    <p>both a and b</p> Signup and view all the answers

    Organic molecules that serve as wetting agents and emulsifiers and can be used as disinfectants if they are cationic are called:

    <p>detergents</p> Signup and view all the answers

    A culture in a closed vessel with a single batch of medium to which no fresh medium is added and no used medium is removed is called a:

    <p>batch culture</p> Signup and view all the answers

    Ultraviolet light damages bacterial cells by affecting the:

    <p>bacterial DNA</p> Signup and view all the answers

    Study Notes

    Chemotherapeutic Agents and Their Activities

    • Chemotherapeutic agents can damage the host through various mechanisms, including plasmid effects, broad-spectrum action, side effects, and antimetabolite activity.
    • Antifungal agents like griseofulvin can combat fungal infections.

    Microbial Identification and Characteristics

    • Some organisms, like Staphylococcus aureus, produce catalase.
    • Others, like Thiobacillus thiooxidans, can convert H2SO4 to H2S.
    • Bacteria reproduce through binary fission.
    • Different organisms have various metabolic pathways

    Antimicrobials and Their Targets

    • Examples of antimalarial drugs include artemisinin.
    • Antibiotics like erythromycin belong to the macrolide class.
    • Reactive oxygen species, such as triplet and singlet oxygen, are toxic forms of oxygen, with some associated with damage to cells.
    • The most probable number method is used to estimate or count bacteria in solutions when they don't easily grow on a plate.

    Antimicrobial Mechanisms and Actions

    • The precursors to GMP and AMP are important components in the synthesis of nucleotides.
    • Some microorganisms are commonly found in specific environments (e.g., Bacillus subtilis in jam), while others prefer specific conditions.
    • Ionizing radiation (e.g., UV light, X-rays, gamma rays) is used for sterilization/killing microorganisms.
    • Heat treatments are important to achieve sterilization, often at high temperatures or pressure for desired results.

    Microbial Growth and Environmental Influences

    • Organisms with a preference for low temperatures, called psychrophiles, are important to consider in certain environments.
    • Inhibitors of nucleotide biosynthesis are substances that block or hinder the production of nucleotides within a cell.
    • These substances are important in medicine and other applications.

    Sterilization and Disinfectants

    • Autoclaves are used for sterilization by employing superheated steam under high pressure.
    • Certain gases (like ethylene oxide) are used for sterilizing equipment or materials.
    • Coenzyme A plays an essential role in cellular processes, including amino acid and lipid synthesis.

    Microbial Physiology and Genetics

    • Psychrophilic bacteria can survive in cold environments.
    • Understanding the role of specific enzymes, such as beta-galactosidase, is important in metabolic processes.
    • High-frequency ultrasonic instruments are tools to disrupt cell structures.
    • Bacterial cells can adapt and thrive; some are resistant to certain chemicals and/or survive under specific conditions.
    • Bacteria can perform cellular respiration, like reducing NADP to NADPH as part of metabolic pathways.

    Microbial Growth Conditions and Applications

    • Organisms with narrow temperature ranges are described as stenothermal.
    • A nitrogenous base with a double-ringed structure is called a purine.
    • Sulfur is essential in various cellular functions including protein synthesis.
    • The technique of sterilization or disinfection involves removing or eliminating microorganisms that can contaminate or cause issues.
    • Understanding of growth conditions like nutrients and temperature range is crucial.

    Microbial Diversity and Identification

    • Different microbial species have varying responses to environmental elements, such as different effects under certain temperatures, pressures, or presence of specific chemicals

    Microbial Interactions and Environmental Adaptations

    • Certain microbes are involved in specific chemical transformations in the environment.
    • Some microbes are important in nutrient cycles.
    • Understanding bacteria's response to oxygen is important for selecting appropriate growth conditions in different experiments, and understanding environments or conditions where they thrive.
    • Determining the presence/absence of specific microbial species or groups in particular habitats helps to understand or diagnose infectious problems.

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    Microbiology Exam 3 PDF

    Description

    Test your knowledge on chemotherapeutic agents, their mechanisms, and the characteristics of various microorganisms. This quiz also covers antimicrobial drugs and their targets, along with methods for microbial estimation. Dive into the world of microbiology and pharmacology with this comprehensive quiz.

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