Podcast
Questions and Answers
What is the primary function of metformin in managing type 2 diabetes?
What is the primary function of metformin in managing type 2 diabetes?
Which serious condition is associated with combining metformin and intravenous contrast material?
Which serious condition is associated with combining metformin and intravenous contrast material?
When should metformin be discontinued relative to a CT scan with contrast?
When should metformin be discontinued relative to a CT scan with contrast?
How does metformin affect insulin sensitivity?
How does metformin affect insulin sensitivity?
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What kind of medication is metformin classified as?
What kind of medication is metformin classified as?
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Study Notes
Metformin and CT Scans
- Metformin is a biguanide oral antidiabetic medication, used as first-line treatment for type 2 diabetes.
- Metformin does not directly lower blood glucose. It works by decreasing glucose production in the liver and increasing tissue responsiveness to insulin.
- Combining metformin with IV contrast material during a CT scan increases the risk of renal toxicity and life-threatening lactic acidosis.
- Therefore, metformin should be held 1-2 days before a CT scan with contrast and for 48 hours afterwards.
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Description
This quiz covers the essential information regarding the use of metformin in patients scheduled for CT scans with IV contrast. Important guidelines regarding the timing of metformin administration around CT scans will be tested. Understanding the risks of renal toxicity and lactic acidosis associated with metformin is crucial for safe clinical practice.
