Glucophage (Metformin) Flashcards

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Questions and Answers

What is the class of Glucophage (metformin)?

  • Analgesic
  • Antidiabetic (correct)
  • Antihypertensive
  • Antibiotic

What is the action of Glucophage (metformin)?

Decrease hepatic glucose production and intestinal glucose absorption.

What is the indication for Glucophage (metformin)?

Management of type two diabetes.

What is the route of administration for Glucophage (metformin)?

<p>PO</p> Signup and view all the answers

What is the typical dosage for Glucophage (metformin)?

<p>500 mg bid.</p> Signup and view all the answers

Which of the following are side effects of Glucophage (metformin)? (Select all that apply)

<p>Hypoglycemia (A), Decrease B12 levels (C), Abdominal bloating (D), Lactic Acidosis (E), Diarrhea (F)</p> Signup and view all the answers

Which substances can interact with Glucophage (metformin)? (Select all that apply)

<p>Ranitidine (A), Nifedipine (B), Digoxin (C), Alcohol (D), Morphine (E)</p> Signup and view all the answers

Which foods are known to interact with Glucophage (metformin)? (Select all that apply)

<p>Chromium (B), Coenzyme Q10 (C), Glucosamine (D)</p> Signup and view all the answers

For patient teaching, patients should take Glucophage at the same time every day and learn how to take their blood sugar levels the right way. If hypoglycemic, they should have a glass of ______ or 2-3 tsp of sugar.

<p>milk</p> Signup and view all the answers

What nursing implications should be monitored when administering Glucophage (metformin)?

<p>Signs and symptoms of lactic acidosis, blood sugar monitoring, and signs of hypoglycemia.</p> Signup and view all the answers

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Study Notes

Glucophage (metformin) Overview

  • Classified as an antidiabetic medication.
  • Primarily prescribed for the management of type 2 diabetes.

Mechanism of Action

  • Decreases hepatic glucose production.
  • Reduces intestinal glucose absorption.

Administration

  • Administered orally (PO).
  • Common dosage is 500 mg twice daily (bid).

Side Effects

  • Can lead to decreased vitamin B12 levels.
  • Possible gastrointestinal effects include abdominal bloating and diarrhea.
  • Potential for hypoglycemia and lactic acidosis.

Drug Interactions

  • Notable interactions with:
    • Digoxin
    • Alcohol
    • Morphine
    • Nifedipine
    • Ranitidine

Food Interactions

  • May interact with supplements and compounds like glucosamine, chromium, and coenzyme.

Patient Education

  • Instruct to take medication at the same time each day.
  • Inform that metformin controls hyperglycemia but does not cure diabetes.
  • Recommended to take with meals to minimize gastrointestinal side effects.
  • Teach proper blood sugar monitoring techniques.
  • In cases of hypoglycemia, suggest a glass of orange juice or 2-3 teaspoons of sugar.
  • Advise on risks for lactic acidosis and signs of severe infection, dehydration, or ongoing diarrhea which may necessitate stopping the medication.

Nursing Implications

  • Monitor for signs of lactic acidosis, including chills, diarrhea, dizziness, decreased blood pressure, and heart rate.
  • Regularly check blood sugar levels.
  • Watch for signs of hypoglycemia in patients.

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