Metformin and CT Scans Overview
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Questions and Answers

What is the primary mechanism by which metformin helps control blood sugar levels?

  • Increasing glucose production in the liver
  • Decreasing glucose absorption in the intestines
  • Decreasing glucose production in the liver (correct)
  • Increasing insulin release from the pancreas
  • Which of the following risks is associated with combining metformin and intravenous (IV) contrast material?

  • Reduction in liver function
  • Increased insulin resistance
  • Increased blood glucose levels
  • Life-threatening lactic acidosis (correct)
  • When should metformin be discontinued prior to a CT scan with contrast?

  • No need to discontinue metformin
  • 1-2 hours before the scan
  • Immediately before the scan
  • 1-2 days before the scan (correct)
  • What is the classification of metformin?

    <p>Biguanide</p> Signup and view all the answers

    What effect does metformin have on tissue responsiveness?

    <p>Increases tissue responsiveness to insulin</p> Signup and view all the answers

    Study Notes

    Metformin and CT Scans

    • Metformin is a biguanide oral antidiabetic medication, often the first-line treatment for type 2 diabetes.
    • Metformin does not directly lower blood glucose but reduces its production in the liver and increases tissue responsiveness to insulin.
    • Combining metformin with IV contrast material for a CT scan increases the risk of renal toxicity and life-threatening lactic acidosis.
    • Metformin should be held 1-2 days before a CT scan with contrast and for 48 hours afterward.

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    Description

    This quiz explores the important considerations for patients taking metformin before undergoing a CT scan with contrast. Understand the risks associated with renal toxicity and lactic acidosis, along with the recommended timing for holding metformin. Gain insights into safe practices for managing diabetes in relation to imaging studies.

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