Ménière Disease Overview and Clinical Manifestations
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Questions and Answers

What is the approximate incidence of Ménière disease, based on the provided information?

  • 0.5-7.5 per 100,000
  • 0.5-7.5 per 1000 (correct)
  • 5-75 per 10,000
  • 5-75 per 1,000,000
  • Which of the following is NOT a potential cause of Ménière disease, according to the provided information?

  • Trauma
  • Genetic predisposition (correct)
  • Infection
  • Drugs or toxins
  • What is the primary lesion location in Ménière disease, according to the provided information?

  • Utricle
  • Cochlear duct
  • Saccule
  • Endolymphatic sac (correct)
  • Which of the following best describes the pathophysiological mechanism of Ménière disease?

    <p>Increased volume of endolymph leading to dilation of the membranous labyrinth (B)</p> Signup and view all the answers

    At what age range does Ménière disease typically manifest?

    <p>Middle Age (40-59 years) (D)</p> Signup and view all the answers

    When diagnosing Ménière disease, what test specifically assesses communication between balance-related sensors and head movement on eye control?

    <p>Videonystagmography (C)</p> Signup and view all the answers

    Which of the following is NOT a common symptom associated with Ménière disease?

    <p>Migraines (B)</p> Signup and view all the answers

    What is the primary focus of Ménière disease treatment?

    <p>Managing symptoms and improving quality of life (A)</p> Signup and view all the answers

    What is the purpose of the glycerol test?

    <p>To evaluate temporary hearing improvement (C)</p> Signup and view all the answers

    Which surgical treatment option is known to cause hearing loss?

    <p>Both A and C (A)</p> Signup and view all the answers

    Which of the following is a non-pharmacological treatment option for Ménière disease?

    <p>Stress reduction (B)</p> Signup and view all the answers

    What does the term 'ototoxicity' refer to?

    <p>Damage to the inner ear caused by certain medications (B)</p> Signup and view all the answers

    What is the most common characteristic of Ménière disease?

    <p>Hearing loss that fluctuates between attacks (A)</p> Signup and view all the answers

    Flashcards

    Ménière disease

    A condition affecting vestibular function characterized by episodes of vertigo, tinnitus, and hearing loss.

    Endolymph

    A fluid within the membranous labyrinth of the inner ear, crucial for hearing and balance.

    Endolymph hydrops

    An increase in the volume of endolymph leading to dilation of the membranous labyrinth.

    Membranous labyrinth rupture

    A tear in the membranous labyrinth allowing endolymph to mix with perilymph.

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    Primary lesion location in Ménière disease

    The primary lesion in Ménière disease is located at the endolymphatic sac.

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    Ménière disease triad

    Key symptoms of Ménière disease include vertigo, tinnitus, and hearing loss.

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    Vertigo

    A sensation of spinning or dizziness often accompanied by nausea and vomiting.

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    Tinnitus

    A ringing or buzzing noise in the ears, which can be constant or intermittent.

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    Sensorineural hearing loss

    Hearing loss often associated with damage to the inner ear or auditory pathways.

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    Videonystagmography

    A test to assess vestibular function by observing eye movements.

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    Diuretic therapy

    A treatment approach to reduce inner ear fluid through medication.

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    Glycerol test

    A diagnostic test involving glycerol to decrease inner ear fluid volume.

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    Vestibular neurectomy

    A surgical procedure that involves severing the vestibular nerve without affecting hearing.

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    Study Notes

    Ménière Disease Overview

    • Ménière disease affects the inner ear, causing vertigo, tinnitus, and hearing loss.
    • Incidence: 0.5-7.5 per 1000, varying with diagnostic criteria.
    • Age of onset: 20-60, affects both genders equally.
    • Cause: Trauma, infection, drugs, or toxins.
    • Endolymphatic hydrops: Increased endolymph volume dilates the membranous labyrinth.
    • This leads to membranous labyrinth rupture and endolymph/perilymph mixing, a key mechanism.
    • Primary lesion location is the endolymphatic sac.

    Clinical Manifestations

    • Often unilateral vestibular dysfunction (one side).
    • Vertigo, ranging in severity from mild to disabling.
    • Nausea and vomiting, often severe.
    • Tinnitus (ringing in the ears).
    • Nystagmus (rapid eye movements).
    • Sensorineural hearing loss (damage to the inner ear).
    • Pressure or pain in the ear.
    • Symptoms can occur daily or infrequently.
    • Attacks typically last less than 24 hours.
    • Periods of remission can last weeks or months between attacks.
    • Hearing loss may become permanent over time.

    Diagnostic Criteria

    • Detailed symptom history.
    • Physical examination.
    • Auditory testing (audiometry) to find hearing loss.
    • Electrocochleography (EcochG): measures electrical potentials in the inner ear in response to sound.
    • Videonystagmography (VNG): measures eye movements to evaluate vestibular function.
    • Glycerol test: oral ingestion of hyperosmolar solution to reduce inner ear fluid volume, often useful in diagnosis.
    • Audiometry: Tests hearing acuity and identifies hearing loss.

    Treatment

    • No cure: Treatment focuses on symptom management.
    • Non-pharmacological:
      • Regulation of body fluid (reduced salt intake).
      • Smoking cessation.
      • Stress reduction.
    • Pharmacological:
      • Antiemetics (to prevent nausea).
      • Diuretics (to reduce endolymph fluid).
      • Drugs to reduce vertigo.
    • Surgical (in severe cases)
      • Ototoxicity (toxic effects on hearing from medications like gentamicin).
      • Vestibular neurectomy (severing the vestibular nerve).
      • Labyrinthectomy (surgical removal of the labyrinth).

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    Related Documents

    Meniere Disease W6 PDF

    Description

    This quiz covers the essential aspects of Ménière disease, including its causes, clinical manifestations, and the mechanisms involved. You will learn about the symptoms, frequency of attacks, and the impact on the inner ear. Test your knowledge of this inner ear condition and its effects on hearing and balance.

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