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Memantine
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Memantine

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Questions and Answers

What is the peak of action for donepezil after oral administration?

  • 3 to 8 hours (correct)
  • 12 hours
  • 24 hours
  • 30 minutes

    • How is the excretion of donepezil and its metabolites mainly carried out?

  • In feces
  • In saliva
  • In sweat
  • In urine (correct)

    • What is a contraindication for the use of galantamine hydrobromide?

  • Hypertension
  • Severe hepatic impairment (correct)
  • Anxiety disorder
  • Diabetes

    • What is a common adverse effect of rabeprazole?

    <p>GI upset such as nausea</p> Signup and view all the answers

    What is a potential effect of anticholinergics on donepezil?

    <p>Decreases its effect</p> Signup and view all the answers

    What is the main function of carbidopa when administered with levodopa?

    <p>Inhibiting peripheral metabolism of levodopa</p> Signup and view all the answers

    What is a potential risk when monoamine oxidase inhibitors are taken with levodopa-carbidopa?

    <p>Hypertensive crisis</p> Signup and view all the answers

    What is the recommended way to administer levodopa-carbidopa to reduce nausea?

    <p>With or just after food</p> Signup and view all the answers

    What are the therapeutic effects of levodopa and other dopaminergic agents?

    <p>Improvement in mobility, balance, posture, gait, speech, handwriting, and self-care ability</p> Signup and view all the answers

    What is a common adverse effect of levodopa?

    <p>Dyskinesia</p> Signup and view all the answers

    How is levodopa converted in the basal ganglia to produce symptom relief?

    <p>To dopamine</p> Signup and view all the answers

    Why is carbidopa administered with levodopa?

    <p>To decrease peripheral metabolism and reduce adverse effects</p> Signup and view all the answers

    What is the mainstay of treatment for Parkinson's disease?

    <p>Levodopa</p> Signup and view all the answers

    What is a potential adverse effect associated with levodopa treatment?

    <p>Dyskinesia</p> Signup and view all the answers

    What are the therapeutic effects of Levodopa-Carbidopa?

    <p>Improvement in mobility, balance, posture, gait, speech, and handwriting</p> Signup and view all the answers

    What are the symptoms of decreased effectiveness of Levodopa medication?

    <p>Ataxic gait, tremors of the hands and fingers, drooling, and masklike facial expressions</p> Signup and view all the answers

    What adverse effects should be minimized by taking Levodopa-Carbidopa with food?

    <p>Anorexia, nausea, and vomiting</p> Signup and view all the answers

    What should patients avoid when taking Levodopa-Carbidopa?

    <p>Multivitamin preparations containing pyridoxine</p> Signup and view all the answers

    What should be assessed in a patient to detect signs of orthostatic hypotension?

    <p>Blood pressure in sitting and standing positions</p> Signup and view all the answers

    What is a common adverse effect of Levodopa-Carbidopa characterized by involuntary movements of the tongue, mouth, and face?

    <p>Dyskinesia</p> Signup and view all the answers

    What is the recommended action to decrease dyskinesia caused by Levodopa-Carbidopa?

    <p>Decrease the dose of the medication</p> Signup and view all the answers

    What can occur after 2 to 5 years of taking Levodopa-Carbidopa?

    <p>The medication may lose its overall effectiveness</p> Signup and view all the answers

    What should be avoided when taking the sustained-release preparation of Levodopa-Carbidopa?

    <p>Crushing the sustained-release preparation</p> Signup and view all the answers

    What is the main purpose of administering carbidopa with levodopa?

    <p>To decrease peripheral metabolism and reduce adverse effects</p> Signup and view all the answers

    What can monoamine oxidase inhibitors do when taken with levodopa-carbidopa?

    <p>Increase the risk of hypertensive crisis</p> Signup and view all the answers

    What are the therapeutic effects of levodopa and other dopaminergic agents?

    <p>Improvement in mobility, balance, posture, gait, speech, handwriting, and self-care ability</p> Signup and view all the answers

    What is a common adverse effect of levodopa?

    <p>Dyskinesia, involuntary movements of the tongue, mouth, and face</p> Signup and view all the answers

    How is levodopa converted in the basal ganglia?

    <p>To dopamine, producing symptom relief by increasing striatal dopaminergic activity</p> Signup and view all the answers

    What is the characteristic response to levodopa medication within 5 to 10 years?

    <p>Development of dyskinesia, including various involuntary movements</p> Signup and view all the answers

    What is the mainstay of treatment for Parkinson's disease?

    <p>Levodopa</p> Signup and view all the answers

    What are potential adverse effects associated with levodopa?

    <p>Nausea, vomiting, appetite loss, decreased blood pressure, dystonia, dyskinesia, and confusion</p> Signup and view all the answers

    What is the effect of carbidopa when added to levodopa?

    <p>Decrease peripheral metabolism of levodopa before it can reach the brain</p> Signup and view all the answers

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