Podcast
Questions and Answers
Which enzyme is responsible for the synthesis of prostaglandins?
Which enzyme is responsible for the synthesis of prostaglandins?
- COX-2
- COX-4
- COX-3
- COX-1 (correct)
Which type of NSAID is known for its selective inhibition of COX-2?
Which type of NSAID is known for its selective inhibition of COX-2?
- Preferential COX-2 inhibitors (correct)
- Salicylates
- Propionic acid derivatives
- Anthranilic acid derivatives
Which NSAID is classified as a pyrazolone derivative?
Which NSAID is classified as a pyrazolone derivative?
- Ketorolac (correct)
- Phenylbutazone
- Ibuprofen
- Naproxen
Which drug is commonly used as an analgesic and antipyretic, but has poor anti-inflammatory action?
Which drug is commonly used as an analgesic and antipyretic, but has poor anti-inflammatory action?
Which drug is contraindicated in pregnant women and peptic ulcer patients?
Which drug is contraindicated in pregnant women and peptic ulcer patients?
Which drug is an alternative to aspirin and is better tolerated orally?
Which drug is an alternative to aspirin and is better tolerated orally?
Which drug is highly bound to plasma proteins and should never be used with anticoagulants?
Which drug is highly bound to plasma proteins and should never be used with anticoagulants?
Which drug is a relatively selective COX2 congener of diclofenac sodium?
Which drug is a relatively selective COX2 congener of diclofenac sodium?
Which of the following is a common side effect of the NSAID described in the text?
Which of the following is a common side effect of the NSAID described in the text?
Which NSAID is recommended for short and long term anti-inflammatory conditions?
Which NSAID is recommended for short and long term anti-inflammatory conditions?
Which NSAID has been observed to cause reversible azotaemia?
Which NSAID has been observed to cause reversible azotaemia?
Which NSAID is a weak inhibitor of prostaglandin synthesis?
Which NSAID is a weak inhibitor of prostaglandin synthesis?
Which of the following is the main mechanism of action of NSAIDs?
Which of the following is the main mechanism of action of NSAIDs?
Which of the following is NOT a property of NSAIDs?
Which of the following is NOT a property of NSAIDs?
Which of the following endogenous agents have been associated with gingivitis, periodontitis, and alveolar bone resorption?
Which of the following endogenous agents have been associated with gingivitis, periodontitis, and alveolar bone resorption?
Which of the following drugs was introduced as an alternative to salicylic acid?
Which of the following drugs was introduced as an alternative to salicylic acid?
Which drug has a COX2:COX1 selectivity ratio of 10?
Which drug has a COX2:COX1 selectivity ratio of 10?
Which drug is a newer congener of piroxicam?
Which drug is a newer congener of piroxicam?
Which drug is labeled as a preferred COX2 inhibitor?
Which drug is labeled as a preferred COX2 inhibitor?
Which drug is effective in treating rheumatoid arthritis, osteoarthritis, and soft tissue injury?
Which drug is effective in treating rheumatoid arthritis, osteoarthritis, and soft tissue injury?
Which of the following is a true statement about the analgesic action of aspirin?
Which of the following is a true statement about the analgesic action of aspirin?
Which of the following is a true statement about the anti-inflammatory action of aspirin?
Which of the following is a true statement about the anti-inflammatory action of aspirin?
Which of the following is a true statement about the metabolism and elimination of aspirin?
Which of the following is a true statement about the metabolism and elimination of aspirin?
Which of the following is a true statement about the side effects of aspirin?
Which of the following is a true statement about the side effects of aspirin?
Which of the following NSAIDs significantly slowed the rate of alveolar bone loss in periodontitis when administered daily for up to 3 years?
Which of the following NSAIDs significantly slowed the rate of alveolar bone loss in periodontitis when administered daily for up to 3 years?
What are the significant side effects associated with long-term NSAID use for periodontal benefits?
What are the significant side effects associated with long-term NSAID use for periodontal benefits?
What happens to the periodontal benefits of long-term NSAID use when patients stop taking the drugs?
What happens to the periodontal benefits of long-term NSAID use when patients stop taking the drugs?
Which type of NSAID causes gastrointestinal ulceration and impaired hemostasis?
Which type of NSAID causes gastrointestinal ulceration and impaired hemostasis?
How long is the necessary duration of extended NSAID use for periodontal benefits to become apparent?
How long is the necessary duration of extended NSAID use for periodontal benefits to become apparent?
What is the term used to describe the return to or acceleration of the rate of bone loss seen before NSAID therapy when patients stop taking the drugs?
What is the term used to describe the return to or acceleration of the rate of bone loss seen before NSAID therapy when patients stop taking the drugs?