Meloxicam and Diclofenac
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Questions and Answers

What is the initial analgesic therapy for most patients with OA?

  • Acetaminophen (correct)
  • Nonselective NSAIDs
  • Tramadol
  • COX-2 enzyme blockers
  • Which medication must be used with caution due to the associated risk of cardiovascular disease and little to no decrease in GI upset?

  • Nonselective NSAIDs
  • Tramadol
  • COX-2 enzyme blockers (correct)
  • Acetaminophen
  • Which medication may be considered for some patients with OA who are refractory to other treatments?

  • Topical diclofenac sodium gel
  • Colchicine
  • Opioids
  • Methotrexate (correct)
  • Which medication is FDA approved for the use of osteoarthritic joint pain in the hands and knees?

    <p>Topical diclofenac sodium gel</p> Signup and view all the answers

    What type of medications are used in conjunction with nonpharmacologic strategies for OA?

    <p>Acetaminophen</p> Signup and view all the answers

    Which medication may be considered for some select patients with OA due to similar pathophysiologic antecedents with other diseases?

    <p>Methotrexate</p> Signup and view all the answers

    What is the main focus of pharmacologic management of OA?

    <p>Symptom management and pain control</p> Signup and view all the answers

    Which medication may be used for OA patients who are refractory to other treatments, despite being typically prescribed for treating RA?

    <p>Methotrexate</p> Signup and view all the answers

    What type of medication is typically the initial analgesic therapy for most patients with OA?

    <p>Acetaminophen</p> Signup and view all the answers

    Which medication is used in conjunction with nonpharmacologic strategies for OA?

    <p>Acetaminophen</p> Signup and view all the answers

    Which medication may be considered for some patients with OA who are refractory to other treatments, despite being typically prescribed for treating gout?

    <p>Colchicine</p> Signup and view all the answers

    Which medication is used for the use of osteoarthritic joint pain in the hands and knees and has been FDA approved?

    <p>Topical diclofenac sodium gel</p> Signup and view all the answers

    Which drug therapy is commonly used for osteoarthritis treatment?

    <p>Aspirin</p> Signup and view all the answers

    What is the main pharmacological action of meloxicam?

    <p>COX-1 and COX-2 inhibition</p> Signup and view all the answers

    What is a contraindication for meloxicam use?

    <p>Known aspirin allergy</p> Signup and view all the answers

    What is a potential adverse effect of meloxicam?

    <p>GI bleeding</p> Signup and view all the answers

    Which medication interaction should be considered when administering meloxicam?

    <p>Alcohol</p> Signup and view all the answers

    What is the purpose of nursing implications for administering meloxicam?

    <p>Assessing for therapeutic effects and adverse reactions</p> Signup and view all the answers

    What is emphasized in patient teaching guidelines for meloxicam?

    <p>Taking the drug with food</p> Signup and view all the answers

    What is the main similarity between meloxicam and diclofenac?

    <p>COX-1 and COX-2 inhibition</p> Signup and view all the answers

    What lacks strong evidence for its efficacy in osteoarthritis treatment?

    <p>Viscosupplementation</p> Signup and view all the answers

    What type of arthritis is meloxicam used for?

    <p>Osteoarthritis and rheumatoid arthritis</p> Signup and view all the answers

    In which patients should dosage adjustments for meloxicam be considered?

    <p>Patients with renal or hepatic impairment</p> Signup and view all the answers

    What is a black box warning for meloxicam?

    <p>Cardiovascular events and GI bleeding</p> Signup and view all the answers

    Study Notes

    Meloxicam: Drug Therapy for Osteoarthritis

    • Osteoarthritis treatment includes drug therapy with medications like aspirin, acetaminophen, NSAIDs, and glucosamine/chondroitin
    • Viscosupplementation, involving injection of hyaluronates into joints, lacks strong evidence for its efficacy
    • Meloxicam is an oxicam derivative, a COX-1 and COX-2 inhibitor, used for osteoarthritis and rheumatoid arthritis
    • Meloxicam's pharmacokinetics, onset of action, and selective COX-2 inhibition in various body sites
    • Dosage adjustments for meloxicam in patients with renal or hepatic impairment
    • Meloxicam's adverse effects, including respiratory, hematologic, and GI effects, as well as FDA black box warnings for cardiovascular events and GI bleeding
    • Contraindications for meloxicam, including known aspirin allergy and postoperative use after coronary artery bypass surgery
    • Medication interactions with meloxicam, such as those with alcohol, garlic, ginger, and lithium
    • Nursing implications for administering meloxicam, including assessing for therapeutic effects and adverse reactions
    • Patient teaching guidelines for meloxicam, emphasizing the importance of taking the drug with food and reporting specific symptoms to healthcare providers
    • Overview of diclofenac, another drug in the same class as meloxicam, with similar COX-1 and COX-2 inhibition and systemic distribution
    • Diclofenac's high absorption rate by the GI tract and distribution into synovial fluid and breast milk

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    Related Documents

    Pharmacologic Therapy PDF

    Description

    Test your knowledge of meloxicam, a drug therapy for osteoarthritis and rheumatoid arthritis. Explore its pharmacokinetics, adverse effects, contraindications, interactions, nursing implications, and patient teaching guidelines. Learn about a similar drug, diclofenac, and its absorption and distribution.

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