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Questions and Answers
What is the initial analgesic therapy for most patients with OA?
Which medication must be used with caution due to the associated risk of cardiovascular disease and little to no decrease in GI upset?
Which medication may be considered for some patients with OA who are refractory to other treatments?
Which medication is FDA approved for the use of osteoarthritic joint pain in the hands and knees?
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What type of medications are used in conjunction with nonpharmacologic strategies for OA?
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Which medication may be considered for some select patients with OA due to similar pathophysiologic antecedents with other diseases?
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What is the main focus of pharmacologic management of OA?
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Which medication may be used for OA patients who are refractory to other treatments, despite being typically prescribed for treating RA?
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What type of medication is typically the initial analgesic therapy for most patients with OA?
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Which medication is used in conjunction with nonpharmacologic strategies for OA?
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Which medication may be considered for some patients with OA who are refractory to other treatments, despite being typically prescribed for treating gout?
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Which medication is used for the use of osteoarthritic joint pain in the hands and knees and has been FDA approved?
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Which drug therapy is commonly used for osteoarthritis treatment?
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What is the main pharmacological action of meloxicam?
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What is a contraindication for meloxicam use?
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What is a potential adverse effect of meloxicam?
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Which medication interaction should be considered when administering meloxicam?
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What is the purpose of nursing implications for administering meloxicam?
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What is emphasized in patient teaching guidelines for meloxicam?
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What is the main similarity between meloxicam and diclofenac?
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What lacks strong evidence for its efficacy in osteoarthritis treatment?
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What type of arthritis is meloxicam used for?
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In which patients should dosage adjustments for meloxicam be considered?
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What is a black box warning for meloxicam?
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Study Notes
Meloxicam: Drug Therapy for Osteoarthritis
- Osteoarthritis treatment includes drug therapy with medications like aspirin, acetaminophen, NSAIDs, and glucosamine/chondroitin
- Viscosupplementation, involving injection of hyaluronates into joints, lacks strong evidence for its efficacy
- Meloxicam is an oxicam derivative, a COX-1 and COX-2 inhibitor, used for osteoarthritis and rheumatoid arthritis
- Meloxicam's pharmacokinetics, onset of action, and selective COX-2 inhibition in various body sites
- Dosage adjustments for meloxicam in patients with renal or hepatic impairment
- Meloxicam's adverse effects, including respiratory, hematologic, and GI effects, as well as FDA black box warnings for cardiovascular events and GI bleeding
- Contraindications for meloxicam, including known aspirin allergy and postoperative use after coronary artery bypass surgery
- Medication interactions with meloxicam, such as those with alcohol, garlic, ginger, and lithium
- Nursing implications for administering meloxicam, including assessing for therapeutic effects and adverse reactions
- Patient teaching guidelines for meloxicam, emphasizing the importance of taking the drug with food and reporting specific symptoms to healthcare providers
- Overview of diclofenac, another drug in the same class as meloxicam, with similar COX-1 and COX-2 inhibition and systemic distribution
- Diclofenac's high absorption rate by the GI tract and distribution into synovial fluid and breast milk
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Description
Test your knowledge of meloxicam, a drug therapy for osteoarthritis and rheumatoid arthritis. Explore its pharmacokinetics, adverse effects, contraindications, interactions, nursing implications, and patient teaching guidelines. Learn about a similar drug, diclofenac, and its absorption and distribution.
