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Meloxicam
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Meloxicam

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Questions and Answers

Which of the following is a common side effect of aspirin at analgesic doses?

  • Increased blood sugar (correct)
  • Decreased blood sugar
  • Increased blood pressure
  • Decreased blood pressure
  • What is the main mechanism of action of aspirin as an analgesic?

  • Activation of opioid receptors
  • Inhibition of COX
  • Reduction of prostaglandin levels (correct)
  • Blockage of nerve impulses
  • Which of the following is a potential side effect of long-term aspirin use?

  • Increased risk of infection
  • Decreased risk of infection
  • Increased risk of bleeding (correct)
  • Decreased risk of bleeding
  • Which of the following is a characteristic of Reye's syndrome?

    <p>Occurs in infants and children</p> Signup and view all the answers

    Which enzyme is inhibited by NSAIDs to relieve pain due to inflammation?

    <p>COX-2</p> Signup and view all the answers

    Which of the following is a non-selective COX inhibitor?

    <p>Ibuprofen</p> Signup and view all the answers

    Which type of NSAID is most frequently used for mild-to-moderate pain?

    <p>Propionic acid derivatives</p> Signup and view all the answers

    Which of the following is a shared toxicity due to prostaglandin synthesis inhibition by NSAIDs?

    <p>Gastric mucosal damage</p> Signup and view all the answers

    Which drug is an alternative to aspirin and is better tolerated orally with low incidences of adverse reactions?

    <p>Ibuprofen</p> Signup and view all the answers

    Which drug is contraindicated in pregnant women and peptic ulcer patients?

    <p>Aspirin</p> Signup and view all the answers

    Which drug is highly bound to plasma proteins and should never be used with anticoagulants?

    <p>Aspirin</p> Signup and view all the answers

    Which drug is commonly used in dentistry to suppress swelling and inflammation after tooth extraction?

    <p>Ibuprofen</p> Signup and view all the answers

    Which of the following is a common side effect of using NSAIDs?

    <p>Gastric ulceration</p> Signup and view all the answers

    What is the mechanism of action of NSAIDs?

    <p>Reversible inhibition of COX</p> Signup and view all the answers

    Which NSAID can be used for parenteral administration?

    <p>Ketorolac</p> Signup and view all the answers

    Which NSAID is a weak inhibitor of prostaglandin synthesis and exerts anti-inflammatory action through other mechanisms?

    <p>Propiphenazone</p> Signup and view all the answers

    Which of the following is a potential side effect of long-term NSAID use for periodontal benefits?

    <p>Gastrointestinal problems</p> Signup and view all the answers

    Which type of NSAID inhibits osteoclastic activity in periodontitis?

    <p>Nonselective NSAIDs</p> Signup and view all the answers

    What happens to the periodontal benefits of long-term NSAID use when patients stop taking the drugs?

    <p>They are lost</p> Signup and view all the answers

    Which of the following drugs is a newer congener of piroxicam and has a COX2:COX1 selectivity ratio of 10?

    <p>Meloxicam</p> Signup and view all the answers

    Which drug should be avoided in the presence of severe hepatic/renal disease and in those receiving rifampin, warfarin, and methotrexate?

    <p>Rofecoxib</p> Signup and view all the answers

    Which drug is a central analgesic and antipyretic, but a poor inhibitor of PG synthesis in peripheral tissues?

    <p>Paracetamol</p> Signup and view all the answers

    Which drug is a good and promptly acting antipyretic, and does not affect platelet function or clotting factors?

    <p>Paracetamol</p> Signup and view all the answers

    Which endogenous agents are involved in the complex mechanism of action of NSAIDs in relation to periodontitis?

    <p>Prostaglandins, bradykinin, histamine, chemotactic factors &amp; superoxide free radicals</p> Signup and view all the answers

    Which properties do NSAIDs possess?

    <p>Anti-inflammatory, analgesic, and antipyretic</p> Signup and view all the answers

    What was the main mechanism of action of NSAIDs discovered by John Vane and co-workers in 1971?

    <p>Blocking prostaglandin generation</p> Signup and view all the answers

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