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What is endomitosis in the context of thrombocytopoiesis?
What is endomitosis in the context of thrombocytopoiesis?
Replication of chromosomes in the absence of nuclear division
What is the significance of the N:C ratio in thrombocytopoiesis?
What is the significance of the N:C ratio in thrombocytopoiesis?
N:C ratio stands for nucleus-cytoplasm ratio, which indicates the stage of megakaryocyte differentiation.
What are a-granules and their importance in platelets?
What are a-granules and their importance in platelets?
Alpha granules; important for adhesion in platelets (50-80 per platelet)
What role do d-granules (dense granules) play in thrombocytopoiesis?
What role do d-granules (dense granules) play in thrombocytopoiesis?
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What is the main feature of the MK-I stage or megakaryoblast?
What is the main feature of the MK-I stage or megakaryoblast?
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Describe the DMS (Demarcation System) in thrombocytopoiesis.
Describe the DMS (Demarcation System) in thrombocytopoiesis.
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What is the unique morphology observed in bone marrow aspirate films during thrombocytopoiesis?
What is the unique morphology observed in bone marrow aspirate films during thrombocytopoiesis?
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What are the functions of procoagulant-laden a-granules in thrombocytopoiesis?
What are the functions of procoagulant-laden a-granules in thrombocytopoiesis?
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What is the disease associated with a lack of a-granules in platelets?
What is the disease associated with a lack of a-granules in platelets?
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How do the plasma membrane blebs and blunt projections in megakaryoblasts resemble platelets?
How do the plasma membrane blebs and blunt projections in megakaryoblasts resemble platelets?
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