Medication Administration and Monitoring

Inhibiting prostaglandin synthesis by impeding cyclooxygenase-2, resulting in anti-inflammatory, analgesic, and antipyretic effects.

The primary indication for Celecoxib is the management of pain and reducing inflammation, which can provide relief from discomfort and improve quality of life.

The nurse must assess the patient for CV risk factors before therapy and obtain a baseline blood pressure, as Celecoxib can increase the risk of hypertension and cardiovascular events.

<p>The recommended dosage and frequency of Celecoxib is 200mg/tab, Q12, P.O. (orally, every 12 hours).</p> Signup and view all the answers

<p>Common side effects of Celecoxib include headache, dizziness, diarrhea, and dyspepsia. Taking the medication with food can help minimize the risk of stomach upset.</p> Signup and view all the answers

<p>Monitoring vital signs and coagulation indicators is crucial to identifying potential signs of allergic reactions, adverse effects, and thromboembolic events.</p> Signup and view all the answers

<p>Inhibits the activity of both COX-1 and COX-2 enzymes, leading to reduced production of precursor molecules for prostaglandins.</p> Signup and view all the answers

<p>Reduces production of precursor molecules for prostaglandins, which are involved in temperature regulation and pain mediation.</p> Signup and view all the answers

<p>Prostaglandins in the hypothalamus are involved in temperature regulation, and Ketorolac's inhibition of COX-1 and COX-2 enzymes reduces their production, thereby contributing to temperature regulation and fever alleviation.</p> Signup and view all the answers

<p>Reduced production of prostaglandins leads to decreased pain mediation, resulting in alleviation of pain and discomfort.</p> Signup and view all the answers

<p>Inhibiting both COX-1 and COX-2 enzymes leads to a more comprehensive reduction in prostaglandin production, resulting in more effective pain relief and anti-inflammatory effects.</p> Signup and view all the answers

<p>Inhibiting COX-1 and COX-2 enzymes can lead to decreased production of prostaglandins that protect the gastrointestinal mucosa and promote platelet aggregation, resulting in increased risk of gastrointestinal upset and bleeding.</p> Signup and view all the answers

<p>Inhibits calcium ion movement across cell membranes of vascular smooth muscle and myocardium during depolarization.</p> Signup and view all the answers

<p>Management of hypertension, including preeclampsia during pregnancy.</p> Signup and view all the answers

<p>Hypersensitivity to Nifedipine or CCB, pregnancy.</p> Signup and view all the answers

<p>Obtain baseline blood pressure, double check physician's order, educate the patient about the purpose and frequency of the drug.</p> Signup and view all the answers

<p>Dizziness, headache, flushing, peripheral edema, nausea, tachycardia.</p> Signup and view all the answers

<p>Effectiveness of the drug by assessing blood pressure, monitor for any signs of adverse reaction.</p> Signup and view all the answers