Medical Microbiology Week 7: Enterobacteriaceae (Shigella sp.)

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Which family does the genus Shigella belong to?

Enterobacteriaceae family

How many species (groups) of Shigella sp. have been identified?

Four species (groups)

Which species of Shigella sp. is responsible for bacillary dysentery?

Members of the genus Shigella

What is the serotype count for Shigella dysenteriae (group A)?

12 serotypes Signup and view all the answers

To which family were Shigella, Salmonella, and Yersinia traditionally grouped together?

They were grouped with Enterobacteriaceae family Signup and view all the answers

According to recent taxonomic studies, what is Shigella closely related to?

Escherichia Signup and view all the answers

What distinguishes the dysenteric stool from profuse watery diarrhea?

Scant and contains blood, mucus, and inflammatory cells Signup and view all the answers

How many organisms of Shigella can cause disease when ingested?

100-200 organisms Signup and view all the answers

How long can Shigellae survive in milk, eggs, cheese, or shrimps?

Up to 30 days Signup and view all the answers

What are the primary routes of spread for Shigellae from a human resource?

Food, fingers, feces, flies, and Fomites Signup and view all the answers

In which age group does Shigellosis primarily occur?

Children younger than 15 years Signup and view all the answers

What bacterial products are involved in the virulence of Shigella sp.?

Invasion plasmids antigens (IpaA, IpaB, IpaC, IpaD) Signup and view all the answers

What is the primary manifestation of Shiga toxin activity?

Damage to the intestinal epithelium Signup and view all the answers

What is produced by Shigella dysenteriae and is identical to verotoxin-1 produced by enterohemorrhagic strains of E. coli?

Shiga neurotoxin Signup and view all the answers

What is the primary event in cell death and killing of host colonic epithelial cells by Shigella?

Invasion Signup and view all the answers

What does the A subunit of Shiga toxin disrupt?

Protein synthesis Signup and view all the answers

What family does the genus Shigella belong to?

Enterobacteriaceae family Signup and view all the answers

How many species (groups) of Shigella sp. have been identified?

Four Signup and view all the answers

What is the primary manifestation of Shiga toxin activity?

Bacillary dysentery Signup and view all the answers

According to recent taxonomic studies, what is Shigella closely related to?

Escherichia Signup and view all the answers

What are the primary agents of bacillary dysentery?

Members of the genus Shigella Signup and view all the answers

Which species of Shigella sp. is responsible for bacillary dysentery?

Shigella dysenteriae (group A) Signup and view all the answers

What is the primary route of spread for Shigellae from a human resource?

food, fingers, feces, flies, or Fomites (clothing, sheets, etc) Signup and view all the answers

What is the primary event in cell death and killing of host colonic epithelial cells by Shigella?

Invasion Signup and view all the answers

What bacterial products are involved in the virulence of Shigella sp.?

Invasion plasmids antigens (IpaA, IpaB, IpaC, IpaD) Signup and view all the answers

What is produced by Shigella dysenteriae and is identical to verotoxin-1 produced by enterohemorrhagic strains of E. coli?

Shiga toxin Signup and view all the answers

What is the primary manifestation of Shiga toxin activity?

Damage to the intestinal epithelium Signup and view all the answers

How long can Shigellae survive in milk, eggs, cheese, or shrimps?

Up to 30 days Signup and view all the answers

In which age group does Shigellosis primarily occur?

Children younger than 15 years Signup and view all the answers

What distinguishes the dysenteric stool from profuse watery diarrhea?

Scant and contains blood, mucus, and inflammatory cells Signup and view all the answers

What is the serotype count for Shigella dysenteriae (group A)?

Group A Signup and view all the answers

What does the A subunit of Shiga toxin disrupt?

Protein synthesis Signup and view all the answers

Medical Microbiology Week 7: Enterobacteriaceae (Shigella sp.)

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Questions and Answers

Which family does the genus Shigella belong to?

How many species (groups) of Shigella sp. have been identified?

Which species of Shigella sp. is responsible for bacillary dysentery?

What is the serotype count for Shigella dysenteriae (group A)?

To which family were Shigella, Salmonella, and Yersinia traditionally grouped together?

According to recent taxonomic studies, what is Shigella closely related to?

What distinguishes the dysenteric stool from profuse watery diarrhea?

How many organisms of Shigella can cause disease when ingested?

How long can Shigellae survive in milk, eggs, cheese, or shrimps?

What are the primary routes of spread for Shigellae from a human resource?

In which age group does Shigellosis primarily occur?

What bacterial products are involved in the virulence of Shigella sp.?

What is the primary manifestation of Shiga toxin activity?

What is produced by Shigella dysenteriae and is identical to verotoxin-1 produced by enterohemorrhagic strains of E. coli?

What is the primary event in cell death and killing of host colonic epithelial cells by Shigella?

What does the A subunit of Shiga toxin disrupt?

What family does the genus Shigella belong to?

How many species (groups) of Shigella sp. have been identified?

What is the primary manifestation of Shiga toxin activity?

According to recent taxonomic studies, what is Shigella closely related to?

What are the primary agents of bacillary dysentery?

Which species of Shigella sp. is responsible for bacillary dysentery?

What is the primary route of spread for Shigellae from a human resource?

What is the primary event in cell death and killing of host colonic epithelial cells by Shigella?

What bacterial products are involved in the virulence of Shigella sp.?

What is produced by Shigella dysenteriae and is identical to verotoxin-1 produced by enterohemorrhagic strains of E. coli?

What is the primary manifestation of Shiga toxin activity?

How long can Shigellae survive in milk, eggs, cheese, or shrimps?

In which age group does Shigellosis primarily occur?

What distinguishes the dysenteric stool from profuse watery diarrhea?

What is the serotype count for Shigella dysenteriae (group A)?

What does the A subunit of Shiga toxin disrupt?

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