Microbiology Week 6: Enterobacteriaceae
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Questions and Answers

Which structure of Enterobacteriaceae is classified by more than 150 different heat-stable somatic O antigens?

  • Lipopolysaccharide O antigens (correct)
  • Flagellar H antigens
  • Heat-labile K antigens
  • Cytoplasmic membrane
  • Which characteristic is shared by most gram-negative enteric bacteria?

  • Presence of peritrichous flagella (correct)
  • Ability to oxidize
  • Production of exotoxins
  • Production of spores
  • What is a key factor for the identification of enteric bacteria?

  • Oxidase positivity
  • Lactose fermentation (correct)
  • Production of spores
  • Ability to reduce nitrate to nitrite
  • Which member of the normal intestinal microbiota is considerably less common than E. coli?

    <p>Proteus</p> Signup and view all the answers

    In which anatomical site can clinically important infections caused by enteric bacteria occur?

    <p>Urinary tract</p> Signup and view all the answers

    Which of the following is NOT a member of the Enterobacteriaceae family?

    <p>Streptococcus</p> Signup and view all the answers

    What is the natural habitat of Enterobacteriaceae?

    <p>Intestinal tract of humans and animals</p> Signup and view all the answers

    Which Enterobacteriaceae organism is part of the normal microbiota and incidentally causes disease?

    <p>Escherichia coli</p> Signup and view all the answers

    What type of organisms are the Enterobacteriaceae in terms of oxygen requirement?

    <p>Facultative anaerobes or aerobes</p> Signup and view all the answers

    Which characteristic is NOT possessed by Enterobacteriaceae?

    <p>Lack complex antigenic structure</p> Signup and view all the answers

    What is the natural habitat of the Enterobacteriaceae?

    <p>intestinal tract of humans and animals</p> Signup and view all the answers

    Name three genera included in the family Enterobacteriaceae.

    <p>Escherichia, Salmonella, Klebsiella</p> Signup and view all the answers

    What type of microorganisms are the Enterobacteriaceae in terms of oxygen requirement?

    <p>facultative anaerobes or aerobes</p> Signup and view all the answers

    What is a key characteristic of the Enterobacteriaceae's antigenic structure?

    <p>complex</p> Signup and view all the answers

    Which enteric organisms are part of the normal microbiota and incidentally cause disease?

    <p>Escherichia coli</p> Signup and view all the answers

    What are the three types of antigens used for classification of Enterobacteriaceae?

    <p>O antigens, K antigens, H antigens</p> Signup and view all the answers

    What are the shared characteristics of Enterobacteriaceae?

    <p>True &amp; opportunistic pathogens, Gram negative rods, Oxidase negative, Facultative organisms, Ferment glucose, Reduce nitrate to nitrite</p> Signup and view all the answers

    What is the main anatomical site of clinically important infections caused by enteric bacteria?

    <p>Urinary tract, biliary tract, and other sites in the abdominal cavity</p> Signup and view all the answers

    Which enteric bacteria are considerably less common than E. coli in the normal intestinal microbiota?

    <p>Proteus, Enterobacter, Klebsiella, Morganella, Providencia, Citrobacter, and Serratia species</p> Signup and view all the answers

    When do the enteric bacteria become pathogenic?

    <p>When they reach tissues outside of their normal intestinal or other less common normal microbiota sites</p> Signup and view all the answers

    Study Notes

    Enterobacteriaceae Overview

    • Over 150 distinct heat-stable somatic O antigens classify the Enterobacteriaceae family.
    • Most gram-negative enteric bacteria share an ability to ferment carbohydrates.
    • Identification of enteric bacteria relies primarily on biochemical testing and antigenic structure.

    Normal Intestinal Microbiota

    • Enterobacter cloacae is a member of the normal intestinal microbiota, occurring less frequently than E. coli.
    • Enteric bacteria can cause clinically important infections primarily in the gastrointestinal tract and urogenital tract.

    Classification and Characteristics

    • Vibrio cholerae is NOT part of the Enterobacteriaceae family, while Escherichia, Klebsiella, and Salmonella are included.
    • The natural habitat of Enterobacteriaceae is primarily the intestines of humans and animals.
    • Enterobacter cloacae is an example of an organism that is part of the normal microbiota but can lead to opportunistic infections.

    Oxygen Requirements

    • Enterobacteriaceae are facultatively anaerobic organisms, allowing them to grow in both aerobic and anaerobic environments.
    • Enterobacteriaceae are characterized by being non-spore forming, which is not typical of many other bacterial families.

    Antigenic Structure

    • Enterobacteriaceae possess a complex antigenic structure featuring three major types of antigens: somatic (O), flagellar (H), and capsular (K) antigens.
    • These antigens are crucial for classification and serotyping of various species within the family.

    Pathogenicity and Infection

    • Organisms like E. coli and Klebsiella can be part of the normal microbiota yet act as opportunistic pathogens under specific circumstances.
    • Enteric bacteria become pathogenic often when they acquire virulence factors or when the host's barriers are compromised.

    Shared Characteristics

    • Shared traits of Enterobacteriaceae include being oxidase-negative, catalase-positive, and typically having glucose as a fermentation product.
    • Clinically important infections due to enteric bacteria mainly occur in the intestines, urinary tract, and sometimes in bloodstream infections.

    Rarity in Intestinal Microbiota

    • Other enteric bacteria such as Enterobacter and Serratia are considerably less common than E. coli within the normal intestinal microbiota.

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    Description

    Test your knowledge on Enterobacteriaceae in Microbiology Week 6 with Dr. Beriwan A. Ali. This quiz covers the characteristics, classification, and medical significance of the Enterobacteriaceae family.

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