Medical Biochemistry and Pathology Quiz
24 Questions
2 Views

Medical Biochemistry and Pathology Quiz

Created by
@FriendlyLapisLazuli

Questions and Answers

Which of the following is NOT typically associated with thrombocytosis?

  • Polycythemia vera
  • Bone marrow disorders
  • Sickle cell anemia (correct)
  • Chronic infection
  • Which stain is incorrectly matched with its use in malaria diagnosis?

  • Sudan black for thick smear (correct)
  • Wright's stain for blood films
  • Giemsa for thin smear
  • Giemsa for thick smear
  • Which enzyme is commonly elevated in a patient experiencing a heart attack?

  • Creatinine kinase (CK) (correct)
  • Amylase
  • Alkaline phosphatase
  • Liver enzyme
  • What clinical finding is suggestive of fungal meningitis?

    <p>Low glucose and high lymphocytes in CSF</p> Signup and view all the answers

    What is the implication of a false negative DAT in Frazer's case?

    <p>Misdiagnosis of hemolytic anemia</p> Signup and view all the answers

    How does Pappenheimer differ from Howell Jolly bodies during staining?

    <p>Pappenheimer stains blue, Howell Jolly does not</p> Signup and view all the answers

    Which of the following bacteria is commonly associated with septicemia?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    Which patient characteristic indicates that neonates do not usually check for HIV antibodies?

    <p>Antibodies below detectable range</p> Signup and view all the answers

    What is the term for the immunity that develops after exposure to a pathogen?

    <p>Acquired immunity</p> Signup and view all the answers

    Which bacteria is most commonly associated with producing abscesses and boils?

    <p>Staphylococci</p> Signup and view all the answers

    In which of the following scenarios might potassium levels appear falsely elevated?

    <p>Blood sample stored overnight before analysis</p> Signup and view all the answers

    What is the primary medium used for cultivating Mycobacterium tuberculosis?

    <p>Lowenstein Jensen acid medium</p> Signup and view all the answers

    What is a common Gram-negative, motile rod in clinical microbiology?

    <p>Pseudomonas aeruginosa</p> Signup and view all the answers

    What is indicated by the presence of anti-HBc in a hepatitis screening?

    <p>Past hepatitis B infection</p> Signup and view all the answers

    In which condition would you find decreased factor VIII levels?

    <p>Hemophilia A</p> Signup and view all the answers

    What is the mechanism of action for β-lactam antibiotics regarding bacterial resistance?

    <p>Decrease in penicillin binding proteins</p> Signup and view all the answers

    Which of the following is NOT classified as a eukaryotic microorganism?

    <p>Bacteria</p> Signup and view all the answers

    What is the primary hormone secreted by the parathyroid gland?

    <p>Parathyroid hormone</p> Signup and view all the answers

    Which of the following methods is commonly used for analyzing electrolytes quantitatively?

    <p>Flame emission photometry</p> Signup and view all the answers

    In blood type cross-matching, what is the purpose of the indirect Coombs test?

    <p>To find antibodies coating the cells</p> Signup and view all the answers

    Which organism is commonly associated with urinary tract infections and can be acquired from normal bowel flora?

    <p>Escherichia coli</p> Signup and view all the answers

    What is the main characteristic finding in the diagnosis of Schistosoma haematobium infestation?

    <p>Characteristic eggs in urine</p> Signup and view all the answers

    Which immune response is characterized by the presence of serum antibodies Anti-A & B?

    <p>Blood group O</p> Signup and view all the answers

    Which condition can lead to a total leukocytic count of less than 4,000/cu.mm?

    <p>Malignancies</p> Signup and view all the answers

    Study Notes

    Immunology and Pathology

    • Type IV Hypersensitivity is characterized by delayed immune response.
    • Thrombocytosis often occurs in conditions like sickle cell anemia.
    • Polymyositis is indicated by proximal muscle inflammation in a patient.
    • Howell Jolly bodies do not stain blue; Pappenheimer bodies do.
    • Antibodies are not checked for HIV in neonates due to low detectability.
    • Creatinine kinase (CK) and lactate dehydrogenase (LDH) are common markers for heart attack.
    • Beta thalassemia major shows no A hemoglobin, with high levels of Hb F.

    Laboratory Techniques and Results

    • Bacterial septicemia is caused by Staphylococcus aureus, E. coli, and Streptococcus pneumoniae.
    • In fungal meningitis, pleocytosis with high lymphocytes and low glucose in CSF indicates an infection.
    • ZN stain for detecting mycobacteria requires decolorization with acid alcohol.
    • Giemsa stain is used for thick smears in malaria diagnosis, contrary to Sudan black.
    • Forward grouping tests unknown red cells against known antisera.
    • The indirect Coombs test identifies coating on cells during cross-matching.

    Microbiology

    • Gram-negative diplococci associated with pulmonary infections include Neisseria meningitidis.
    • Bacillus anthracis is a Gram-positive, spore-forming bacterium that can cause diarrhea.
    • Pseudomonas aeruginosa is a motile Gram-negative rod bacterium.
    • Mycobacterium tuberculosis is best cultured on Lowenstein Jensen medium.

    Blood and Coagulation

    • Factor VIII is decreased in Hemophilia A.
    • Thrombocytopenia is indicated by a leukocyte count below 4,000/cu.mm in malignancies.
    • Schistosoma haematobium infestation is diagnosed through characteristic eggs in urine.
    • The parathyroid gland secretes parathyroid hormone, crucial in calcium balance.

    Miscellaneous

    • The principle of spectrophotometry is based on the proportionality of light absorption to the substance's concentration.
    • Anisocytosis refers to variations in cell size observed in blood smears.
    • Anti-A and B antibodies are typically found in individuals with blood type O.
    • Artificial barriers in agglutination reactions can include latex particles and erythrocytes coated with antigens.
    • The most common methods for quantitative electrolyte analysis involve flame emission photometry and ion-selective electrode techniques.

    Additional Concepts

    • Resistance to β-lactam antibiotics often arises from decreased penicillin-binding protein.
    • The terms "adaptive immunity" and "acquired immunity" are interchangeable.
    • In Glanzmann's thrombasthenia, the defect lies in platelet aggregation.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    Test your knowledge on various topics in medical biochemistry and pathology. This quiz covers key concepts such as delayed-type hypersensitivity and specific disease conditions like thrombocytosis. Assess your understanding of laboratory practices and color coding in hazard symbols.

    Use Quizgecko on...
    Browser
    Browser