Medical Bacteriology: Pathogens and Infections
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Questions and Answers

A patient presents with severe cellulitis. Which of the following pathogens is the MOST likely cause of this infection?

  • Proteus mirabilis
  • Klebsiella pneumoniae
  • Aliivibrio vulnificus (correct)
  • Salmonella enterica

A hospital is experiencing an outbreak of pneumonia among its patients. Cultures reveal a Gram-negative bacterium resistant to multiple antibiotics. Which of the following organisms is MOST likely responsible for this outbreak?

  • Shigella spp.
  • Klebsiella pneumoniae (correct)
  • Helicobacter pylori
  • Yersinia pestis

A patient is diagnosed with a urinary tract infection (UTI). The causative agent is identified as a bacterium known to produce urease. Which of the following organisms is MOST likely responsible for this patient's infection?

  • Bdellovibrio spp.
  • Proteus mirabilis (correct)
  • Campylobacter jejuni
  • Borrelia burgdorferi

Several people who attended a poultry cookout develop severe intestinal enteritis. Which of the following bacteria is the MOST likely cause of this outbreak?

<p>Campylobacter jejuni (A)</p> Signup and view all the answers

A researcher is studying a bacterium capable of parasitizing other Gram-negative bacteria. This bacterium attaches to the outer membrane of its prey, eventually killing it. Which of the following organisms exhibits this predatory behavior?

<p>Bdellovibrio spp. (B)</p> Signup and view all the answers

A patient presents with symptoms of headache, fever, and rash after a recent tick bite. Which of the following organisms is the MOST likely causative agent?

<p>R. rickettsii (C)</p> Signup and view all the answers

A lab technician is tasked with culturing Neisseria spp.. Which of the following media would be MOST appropriate for this purpose?

<p>Chocolate agar (A)</p> Signup and view all the answers

Which of the following mechanisms is primarily responsible for the pathogenesis of Bordetella pertussis?

<p>Paralysis of the movement of cilia (C)</p> Signup and view all the answers

A hospital patient undergoing treatment for cystic fibrosis develops a severe respiratory infection. Cultures reveal the presence of a Gram-negative bacterium known for its antibiotic resistance. Which of the following organisms is the MOST likely culprit?

<p>Buckholderia cepacia (C)</p> Signup and view all the answers

A burn patient develops a severe wound infection characterized by bluish-green pus and a fruity odor. Which of the following organisms is the MOST likely cause?

<p>Pseudomonas aeruginosa (A)</p> Signup and view all the answers

A researcher isolates a bacterial strain capable of degrading xenobiotics. Which of the following organisms is MOST likely to exhibit this capability?

<p>P.putida (C)</p> Signup and view all the answers

Following a dog bite, a patient develops a localized skin infection with rapid onset. Which of the following organisms is the MOST likely causative agent?

<p>Pasteurella multocida (A)</p> Signup and view all the answers

A patient presents with severe diarrhea and dehydration after consuming contaminated seafood. The stool sample reveals a comma-shaped bacterium. Which of the following organisms is the MOST likely cause?

<p>Vibrio parahaemolyticus (B)</p> Signup and view all the answers

How does Staphylococcus epidermidis contribute to the health of human skin?

<p>By producing antibacterials, creating an environment where other bacteria struggle to survive. (C)</p> Signup and view all the answers

Lactobacillus spp. plays a crucial role in maintaining vaginal health. What is the primary mechanism through which it achieves this?

<p>Producing lactic acid, which lowers the vaginal pH and inhibits the growth of pathogenic yeast and bacteria. (B)</p> Signup and view all the answers

Which characteristic is shared by both Rickettsia spp. and Chlamydia trachomatis?

<p>Both are intracellular parasites. (B)</p> Signup and view all the answers

What distinguishes Rickettsia prowazekii from other species of Rickettsia?

<p>It is transmitted by lice and causes epidemic typhus. (A)</p> Signup and view all the answers

How does Bacteroides thetaiotaomicron benefit humans?

<p>By breaking down complex polysaccharides that humans are unable to digest. (C)</p> Signup and view all the answers

Which characteristic of Mycobacterium contributes most to its antibiotic resistance and slow growth?

<p>The presence of mycolic acid in its cell wall. (B)</p> Signup and view all the answers

Why is Escherichia coli considered both a mutualist and a parasite?

<p>Because some strains produce vitamin K, while other strains cause diseases like hemolytic uremic syndrome. (B)</p> Signup and view all the answers

A patient presents with difficulty breathing due to pseudomembranes in their throat. Which bacterium is the MOST likely cause?

<p><em>Corynebacterium diphtheriae</em> (B)</p> Signup and view all the answers

What is the key characteristic of Rhizobium that makes it beneficial in agriculture?

<p>Its ability to fix atmospheric nitrogen in the roots of legumes, increasing soil fertility. (D)</p> Signup and view all the answers

A newborn develops pneumonia, sepsis, and meningitis shortly after birth. Which bacterium is the MOST likely causative agent?

<p><em>Streptococcus agalactiae</em> (C)</p> Signup and view all the answers

How is Chlamydia trachomatis typically transmitted?

<p>Through sexual contact or from mother to child during birth. (C)</p> Signup and view all the answers

Which of the following is a key characteristic differentiating phototrophic bacteria?

<p>Their differentiation based on proteo/nonproteo,sulfur/nonsulfur usage,and color pigments. (B)</p> Signup and view all the answers

Which genus of bacteria is known for its role as a probiotic in yogurt and for competitively excluding harmful bacteria in the GI tract, vagina, and mouth?

<p><em>Bifidobacterium</em> (D)</p> Signup and view all the answers

A patient who recently completed a course of strong antibiotics develops severe diarrhea. Which bacterium is MOST likely responsible?

<p><em>Clostridium difficile</em> (B)</p> Signup and view all the answers

Which of the following bacterial species is MOST associated with dental caries (cavities)?

<p><em>Streptococcus mutans</em> (C)</p> Signup and view all the answers

How does Clostridium tetani cause spastic paralysis?

<p>By producing toxins that prevent the stopping of muscle contractions. (B)</p> Signup and view all the answers

Which of the following characteristics is NOT associated with Staphylococcus epidermidis?

<p>Production of enterotoxins. (B)</p> Signup and view all the answers

Which scientist is credited with popularizing the idea that 'all cells come from other cells,' even though they weren't the originator?

<p>Rudolf Virchow (D)</p> Signup and view all the answers

What is the primary function of peptidoglycan in bacterial cell walls?

<p>Protecting the cell from osmotic lysis and providing structural support. (C)</p> Signup and view all the answers

Which of the following arrangements is NOT a recognized form for bacilli bacteria?

<p>Staphylobacillus (A)</p> Signup and view all the answers

In Gram staining, what is the purpose of using iodine?

<p>To act as a mordant, forming a complex with crystal violet and trapping it in the cell wall. (B)</p> Signup and view all the answers

How do non-photosynthetic bacteria obtain energy?

<p>By utilizing energy from organic and inorganic chemical compounds. (B)</p> Signup and view all the answers

What is the significance of the Rayleigh Criterion in microscopy?

<p>It specifies the conditions under which two points of light are just resolvable as distinct entities. (C)</p> Signup and view all the answers

Which of the following inclusions found in prokaryotic cells is associated with buoyancy?

<p>Gas vacuoles (B)</p> Signup and view all the answers

What role did Ignaz Semmelweis play in the history of microbiology and medicine?

<p>He demonstrated that hand washing prevents disease transmission. (B)</p> Signup and view all the answers

Which of the following describes secondary active transport in bacteria?

<p>Relies on the electrochemical gradient established by another molecule's transport to move a different molecule against its concentration gradient. (C)</p> Signup and view all the answers

Which of the following is NOT a unique characteristic of prokaryotic cells compared to eukaryotic cells?

<p>70S ribosomes. (C)</p> Signup and view all the answers

Which of the following scientists provided evidence supporting the endosymbiotic theory?

<p>Lynn Margulis (A)</p> Signup and view all the answers

Considering the electromagnetic spectrum, where does visible light fall in relation to infrared and ultraviolet radiation?

<p>Visible light falls between infrared and ultraviolet radiation in terms of frequency. (B)</p> Signup and view all the answers

What is the function of Nucleoid-Associated Proteins (NAPs) in prokaryotic cells?

<p>To hold and compact DNA within the nucleoid region. (C)</p> Signup and view all the answers

What is the correct way to write a species name using binomial nomenclature?

<p><em>Genus species</em> (D)</p> Signup and view all the answers

Flashcards

Rhizobium

Nitrogen-fixing bacteria that live in legume roots.

Bacteroides thetaiotamicron

Mutualist in human gut that breaks down complex polysaccharides.

Escherichia coli (E. coli)

Can be a mutualist producing vitamin K or cause diseases.

Staphylococcus epidermidis

Mutualist on human skin that produces antibacterials.

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Lactobacillus spp.

Dominant bacteria in the vaginal microbiota, produces lactic acid.

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Chlamydia trachomatis

Causes trachoma and a contagious sexually transmitted infection.

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Rickettsia spp.

Obligate intracellular parasites transmitted by arthropod bites.

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Neisseria gonorrhoeae

Bacteria that causes gonorrhea.

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Pseudomonas aeruginosa

Obligate aerobe causing infections, known for antibiotic resistance.

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Vibrio cholerae

Causes cholera resulting in severe diarrhea and dehydration.

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Clostridium tetani

Causes tetanus, resulting in muscle spasms.

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Eukaryotes

Cells that have a nucleus, belong to the domain Eukarya.

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Prokaryotes

Organisms lacking a nucleus, found in bacteria and archaea.

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Cell Theory

States that all living things are made of cells and come from other cells.

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Endosymbiotic Theory

Mitochondria and chloroplasts originated from prokaryotes.

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Gram Staining

Differentiates bacteria into gram-positive and gram-negative based on cell wall structure.

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Filamentous Appendages

Structures on bacteria that aid in movement, attachment, and genetic exchange.

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Lactose Fermentation

Diverse capability among Enterobacteriaceae to ferment lactose completely or partially.

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Plasmids

Small circles of DNA in prokaryotes that carry extra genes.

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Pathogenic Bacteria

Bacteria that cause disease in hosts.

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Microscopic

Organisms or structures less than 100 micrometers in size.

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Photosynthetic Bacteria

Bacteria that use sunlight for energy, producing oxygen as a by-product.

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Active Transport

Movement of molecules against a concentration gradient that requires energy.

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Facultative Anaerobes

Microorganisms that can live with or without oxygen.

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Nucleoid

Non-membrane bound region of prokaryotes containing DNA.

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Escherichia coli

Bacteria that can be a mutualist or a parasite, associated with vitamin K and diseases.

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Neisseria spp.

Fastidious cocci living on mucosal surfaces; found in chocolate agar.

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Bordetella pertussis

Causes whooping cough by paralyzing cilia movement.

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Yersinia pestis

Causes bubonic plague, transmitted by flea bites.

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Bifidobacterium

Mutualistic bacteria abundant in the GI tract, used in probiotics.

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Cyanobacteria

Photosynthetic bacteria that produce oxygen and fix nitrogen.

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Mycobacterium tuberculosis

Causes tuberculosis, known for drug resistance.

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Prokaryotic cells

Cells lacking a nucleus, found in bacteria and archaea.

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Eukaryotic cells

Cells with a nucleus, found in plants, animals, and fungi.

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Gene transfer (pilus)

Bacterial structure that allows genetic material exchange between cells.

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Inclusions

Organelles in prokaryotic cells that assist in identifying organisms.

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Sporulation

Process forming resistant endospores in bacteria.

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Antibiotic resistance

Ability of bacteria to survive treatment with antibiotics.

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Cell wall

Protective layer made of peptidoglycan found in bacteria.

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Vaccination impact

Prevention method using weakened pathogens to promote immunity.

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Microbial metabolism

Chemical processes of bacteria that involve energy conversion and nutrient processing.

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Hemolytic bacteria

Bacteria that can break down red blood cells, classified by their effect.

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Biofilm

A community of microorganisms living together on a surface.

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Rickettsia prowazekii

Causes epidemic typhus, transmitted by lice.

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Rickettsia rickettsii

Causes Rocky Mountain spotted fever, transmitted by ticks.

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Helicobacter pylori

Survives in stomach acid, can cause gastritis and ulcers.

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Calorimetry

Measurement of heat as an indicator of energy changes.

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Diphtheria

Caused by Corynebacterium diphtheriae, leads to throat pseudomembranes.

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Salmonella enterica

Common foodborne pathogen causing diarrhea.

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Listeria monocytogenes

Causes listeriosis, particularly dangerous for pregnant women.

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Streptococcus pneumoniae

Alpha-hemolytic bacteria that causes pneumonia.

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Clostridium botulinum

Causes botulism, leading to flaccid paralysis.

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Escherichia coli O157:H7

Pathogenic E. coli strain linked to foodborne illness.

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Streptococcus mutans

Causes dental caries by fermenting sugars.

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Enterococcus faecalis

Normal gut inhabitant, can cause opportunistic infections.

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Listeria

Gram-positive bacteria that can lead to severe illness.

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Actinomyces

Anaerobic bacteria important in soil and causes periodontitis.

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Neisseria meningitidis

Causes bacterial meningitis, bacterial infection of the brain.

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Staphylococcus aureus

Common pathogen causing skin infections and food poisoning.

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Clostridium difficile

Causes severe diarrhea in antibiotic-treated patients.

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Listeria

Foodborne pathogen often found in unpasteurized products.

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Vibrio parahaemolyticus

Causes gastrointestinal disease from undercooked seafood.

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Campylobacter jejuni

Common cause of food poisoning linked to poultry.

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Corynebacterium diphtheriae

Causes diphtheria, leading to throat pseudomembrane formation.

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Treponema pallidum

Causes syphilis, a sexually transmitted infection.

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Bacillus anthracis

Causes anthrax, used as a bioterrorism agent.

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Rickettsia typhi

Causes endemic murine typhus, transmitted by rat fleas.

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Buckholderia cepacia

Known for nosocomial infections in cystic fibrosis patients.

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Pseudomonas fluorescens

Glows; often found in soil and water environments.

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Aliivibrio fischeri

Symbiotic bacteria with squid that produce light.

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Legionella pneumophila

Bacteria causing Legionnaires' disease, spread via aerosols in warm pools.

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Shigella spp.

Bacteria causing dysentery characterized by diarrhea with blood and mucus.

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Klebsiella pneumoniae

Causes nosocomial infections and antibiotic-resistant pneumonia.

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Microcystis spp.

Genus of cyanobacteria that produces toxins causing liver tumors.

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Mycobacterium leprae

Causes Hansen's disease (leprosy) leading to nerve damage.

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Streptococcus pyogenes

Group A strep causing bacterial pharyngitis (strep throat).

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Actinomyces spp.

Important in soil ecology, some are opportunistic pathogens in humans.

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Lactobacillus acidophilus

A species of Lactobacillus that promotes human health and is commonly found in yogurt as a probiotic.

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MRSA

Methicillin Resistant Staphylococcus Aureus, a strain resistant to multiple antibiotics.

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Gram-positive bacteria

Bacteria with a thick cell wall that retain violet stain during Gram staining.

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Gram-negative bacteria

Bacteria with a thin cell wall that do not retain violet stain, appearing pink after staining.

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Acid Fast Staining

A staining technique used to differentiate two types of Gram-positive cells based on cell wall structure.

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Prokaryotic Ribosomes

Ribosomes in prokaryotes that are smaller (70s) and are the site of protein synthesis.

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Types of Microorganisms

Includes bacteria, archaea, eukaryotes, viruses, and more, each categorized by structure and function.

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Taxonomy Hierarchy

The system of classifying living organisms into categories: Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species.

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