Podcast
Questions and Answers
What is a bacterial infection?
What is a bacterial infection?
It is the invasion of the body by pathogenic bacteria and the development of pathological changes
What are the routes of exogenous infection?
What are the routes of exogenous infection?
- Skin and mucus membrane contact
- Inhalation
- Ingestion
- All of the above (correct)
Which of the following are examples of bacteria that are normally present in the body?
Which of the following are examples of bacteria that are normally present in the body?
- Streptococcus viridans
- Pneumococci
- E. coli
- All of the above (correct)
Which of the following is an effect of infection?
Which of the following is an effect of infection?
What is toxemia?
What is toxemia?
Which of the following bacteria produces exotoxins?
Which of the following bacteria produces exotoxins?
What releases endotoxins?
What releases endotoxins?
Which of the following is a manifestation of bacterial infection?
Which of the following is a manifestation of bacterial infection?
Bacteremia is the transient presence of a large number of bacteria in the bloodstream with toxic manifestations.
Bacteremia is the transient presence of a large number of bacteria in the bloodstream with toxic manifestations.
What occurs when bacteria enter the blood from a septic focus?
What occurs when bacteria enter the blood from a septic focus?
In bacteremia, bacteria are phagocytosed by the reticulo-endothelial system.
In bacteremia, bacteria are phagocytosed by the reticulo-endothelial system.
Which of the following is a pyogenic bacteria?
Which of the following is a pyogenic bacteria?
Which is a symptom of septicemia?
Which is a symptom of septicemia?
What causes sapraemia?
What causes sapraemia?
Flashcards
Bacterial Infection
Bacterial Infection
Invasion of the body by pathogenic bacteria causing changes.
Exogenous Infection
Exogenous Infection
Infection from external sources like environment or carriers.
Endogenous Infection
Endogenous Infection
Infection from bacteria normally present in the body.
Routes of Infection
Routes of Infection
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Inflammation
Inflammation
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Toxemia
Toxemia
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Exotoxins
Exotoxins
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Endotoxins
Endotoxins
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Manifestations of Infection
Manifestations of Infection
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Bacteraemia
Bacteraemia
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Septicemia
Septicemia
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Causative Organisms
Causative Organisms
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Effect of Bacteraemia
Effect of Bacteraemia
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Effect of Septicemia
Effect of Septicemia
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Pyaemia
Pyaemia
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Sapraemia
Sapraemia
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Pathological Picture
Pathological Picture
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Anaemia from Infection
Anaemia from Infection
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Necrosis
Necrosis
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Hemolysis
Hemolysis
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Leukocytosis
Leukocytosis
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Leucopenia
Leucopenia
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Capillary Destruction
Capillary Destruction
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Acute Bacterial Endocarditis
Acute Bacterial Endocarditis
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Multiple Small Abscesses
Multiple Small Abscesses
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Defense Mechanisms of the Body
Defense Mechanisms of the Body
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Significance of Adrenal Gland Integrity
Significance of Adrenal Gland Integrity
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Tissue Degeneration
Tissue Degeneration
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Circulation of Toxins
Circulation of Toxins
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Septic Focus
Septic Focus
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Study Notes
Bacterial Infection
- Bacterial infection is the invasion of the body by pathogenic bacteria, leading to pathological changes.
- Exogenous infections originate from the environment or infected individuals.
- Routes of infection include skin/mucus membrane contact, inhalation, and ingestion.
- Endogenous infections are caused by bacteria normally present in the body, such as Streptococcus viridans, Pneumococci, and E. coli. These infections occur when the body's defense mechanisms are overwhelmed.
Effects of Infection
- Inflammation: A reaction to tissue damage.
- Toxemia: The presence of bacterial toxins in the blood, causing pathological and clinical symptoms.
- Bacteremia: Bacteria in the blood, without significant toxic manifestations.
- Septicemia: The circulation and multiplication of virulent bacteria and their toxins in the blood, a highly fatal condition.
- Sapremia: The presence of toxic metabolites in the bloodstream from the breakdown of necrotic tissue by saprophytic bacteria. This often occurs in gangrene.
Types of Bacterial Toxins
- Exotoxins: Produced by gram-positive bacteria, such as Diphtheria bacilli, Shigella, Streptococci, and Staphylococci.
- Endotoxins: Released from the bodies of dead gram-negative bacteria, like Typhoid bacilli.
Manifestations of Bacterial Infection
- Symptoms of infection may include fever, headache, weakness, and increased metabolic rate.
- Damage may occur to organs such as the heart, kidney, liver, and adrenal cortex.
- Other signs include anemia, bone marrow depression, necrosis, hemorrhage, and swelling of the spleen. Adrenal cortex necrosis is often a fatal consequence.
Bacteraemia
- Transient presence of a small number of bacteria in the bloodstream, without significant toxic effects.
- Bacteria typically enter the blood from an infection site, such as tonsillitis, sinusitis, or a tooth extraction.
- The body's reticulo-endothelial system often phagocytoses the bacteria. Locally, they can cause lesions like osteomyelitis or subacute bacterial endocarditis.
Septicemia
- The circulation and multiplication of a large number of virulent bacteria and their toxins in the blood.
- This condition is highly fatal.
Pyaemia
- Circulation of septic emboli (blood clots) in the bloodstream.
- Emboli lodge in various organs, causing small abscesses.
- Has a high mortality rate.
- Pyogenic bacteria, notably Staphylococcus, are commonly implicated.
Pathological Picture
- Affected organs can show multiple small abscesses (lung, kidney, liver, brain).
- Toxemia leads to organ degeneration.
- Leukocytosis (increased white blood cells) may indicate infection, while leukopenia (decreased white blood cells) is more often a result of toxemia.
Causative Organisms
- Pyogenic bacteria (e.g., Streptococci, Staphylococci, Pneumococci)
- Bacilli (e.g., Bacillus proteus, Bacillus anthrax, Bacillus pestis)
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Description
Test your knowledge on bacterial infections, including their origins, symptoms, and effects on the body. Explore the distinction between exogenous and endogenous infections, as well as the implications of toxemia and septicemia. This quiz covers key concepts related to pathogenic bacteria and their impact on health.