30 Questions
What is the term for the smallest infectious agent that contains only one kind of nucleic acid?
Virus
What is the purpose of the coat proteins in a virus?
To assemble to form the capsid and encase the viral nucleic acid
What is the term for the entire infectious unit of a virus?
Virion
What is the size of the RNA genome in Astroviridae?
6.8–7.0 kb
What is the function of the lipid-containing membrane in a virus?
To facilitate the attachment and penetration of the virus into the host cell
What is the term for the protein-nucleic acid complex that represents the packaged form of the viral genome?
Nucleocapsid
Which family of viruses has a linear, double-stranded, segmented RNA genome?
Reoviridae
What is the characteristic surface feature of Astroviridae particles?
Star-shaped outline
What is the size range of viruses in diameter?
20-300 nm
Which virus family lacks a genome linked protein (VPg)?
Hepeviridae
What is a characteristic of diploid cell lines?
They retain their normal chromosome pattern
What is the size of the particles in Picobirnaviridae?
35–40 nm
Which virus family is associated with gastroenteritis in humans and Colorado tick fever in animals?
Reoviridae
Which of the following is not a cytopathic effect of virus infection?
Hemagglutination
What is the purpose of hemadsorption?
To detect virus-encoded proteins
What type of virus causes focal areas of swollen, rounded cells in monolayers of cultured cells?
Herpesvirus
Which of the following is a method of detecting virus-specific nucleic acid?
Polymerase chain reaction
What type of cell line is derived from diploid or malignant tissues and can grow indefinitely?
Continuous cell line
What is the primary function of receptor molecules on the cell's surface?
To determine cell tropism and viral pathogenesis
What occurs shortly after penetration in the viral replication cycle?
Uncoating
What is unique about negative-strand viruses?
They lack enzymes for mRNA synthesis
What is the result of the morphogenesis step in the viral replication cycle?
Progeny virus formation
What is the purpose of the attachment step in the viral replication cycle?
To bind to specific receptor sites
What is a characteristic of the synthesis of viral components?
It occurs in a highly organized sequence
What is a major concern regarding the use of animal organs as xenografts in humans?
The potential introduction of new viral pathogens
What is a characteristic of bioterrorism agents?
They can be genetically modified to increase virulence
Which of the following is NOT an example of a viral agent that could be used for bioterrorism?
Hepatitis
What is a public health measure that can contribute to the emergence of new viral strains?
Curtailment of prevention programs
Which of the following is an example of a bacterial agent that could be used for bioterrorism?
Anthrax
What is a risk category of bioterrorism agents?
Viral agents like smallpox and hemorrhagic fevers
Learn about the smallest infectious agents, containing only one kind of nucleic acid as their genome. Understand the structure and components of a virion, including the nucleic acid and protein shell. Test your knowledge of viruses and microbiology!
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