Mechanism of Action and Combination of Antibiotics Quiz
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Questions and Answers

How are macrolides like Erythromycin and Azithromycin absorbed in the body?

  • Metabolized by the kidneys
  • Readily absorbed and stable in stomach acid (correct)
  • Destroyed by stomach acid
  • Excreted unchanged in feces
  • What is the mechanism of action of macrolides like Erythromycin and Azithromycin?

  • Promote bacterial DNA replication
  • Inhibit viral replication
  • Inhibit bacterial protein synthesis (correct)
  • Enhance bacterial cell wall synthesis
  • Which macrolide is excreted in the urine instead of bile?

  • Erythromycin
  • Azithromycin
  • Clarithromycin (correct)
  • None of the above
  • Why is Azithromycin preferred over Erythromycin for severe infections or immunocompromised patients?

    <p>Azithromycin has a long half-life and is concentrated in immune cells</p> Signup and view all the answers

    In dentistry, which macrolide is preferred as an alternative to penicillin for allergic patients?

    <p>Erythromycin</p> Signup and view all the answers

    What happens when Erythromycin is used in combination with the anticoagulant drug Warfarin?

    <p>Improves the effect of anticoagulant</p> Signup and view all the answers

    Why is Clarithromycin not preferred for severe infections or immunocompromised patients?

    <p>It is excreted in the urine and not bile</p> Signup and view all the answers

    Why are macrolides considered safe in renal dysfunction patients?

    <p>Stability in stomach acid and liver metabolism</p> Signup and view all the answers

    How do macrolides like Erythromycin and Azithromycin affect bacterial growth?

    <p>Inhibit bacterial protein synthesis</p> Signup and view all the answers

    What can result from combining macrolides with penicillin?

    <p>Antagonized bactericidal effect of penicillin</p> Signup and view all the answers

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