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Mechanism of Action and Combination of Antibiotics Quiz

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Mechanism of Action and Combination of Antibiotics Quiz

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Questions and Answers

How are macrolides like Erythromycin and Azithromycin absorbed in the body?

Metabolized by the kidneys

Readily absorbed and stable in stomach acid (correct)

Destroyed by stomach acid

Excreted unchanged in feces

What is the mechanism of action of macrolides like Erythromycin and Azithromycin?

Promote bacterial DNA replication

Inhibit viral replication

Inhibit bacterial protein synthesis (correct)

Enhance bacterial cell wall synthesis

Which macrolide is excreted in the urine instead of bile?

Erythromycin

Azithromycin

Clarithromycin (correct)

None of the above

Why is Azithromycin preferred over Erythromycin for severe infections or immunocompromised patients?

Azithromycin has a long half-life and is concentrated in immune cells (C) Signup and view all the answers

In dentistry, which macrolide is preferred as an alternative to penicillin for allergic patients?

Erythromycin (B) Signup and view all the answers

What happens when Erythromycin is used in combination with the anticoagulant drug Warfarin?

Improves the effect of anticoagulant (A) Signup and view all the answers

Why is Clarithromycin not preferred for severe infections or immunocompromised patients?

It is excreted in the urine and not bile (C) Signup and view all the answers

Why are macrolides considered safe in renal dysfunction patients?

Stability in stomach acid and liver metabolism (C) Signup and view all the answers

How do macrolides like Erythromycin and Azithromycin affect bacterial growth?

Inhibit bacterial protein synthesis (A) Signup and view all the answers

What can result from combining macrolides with penicillin?

Antagonized bactericidal effect of penicillin (A) Signup and view all the answers