Antibiotics and Mechanism of Action
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Questions and Answers

What is a key requirement for an antibiotic to be effective?

  • It must not affect humans (correct)
  • It must be produced by one microbe that adversely affects other microbes
  • It must be bactericidal
  • It must be effective against viruses

What is the term for the minimum concentration of an antibiotic that prevents the growth of a microorganism?

  • Minimal lethal concentration
  • Minimal inhibitory concentration (correct)
  • Bacteriostatic concentration
  • Bactericidal concentration

What is the purpose of the Kirby-Bauer Disk Susceptibility test?

  • To test the sensitivity of bacteria to multiple antibiotics (correct)
  • To test the effect of antibiotics on bacterial DNA synthesis
  • To measure the minimal inhibitory concentration of an antibiotic
  • To determine the bactericidal or bacteriostatic nature of an antibiotic

What is the mode of action of beta-lactam antibiotics such as penicillin?

<p>They bind to penicillin-binding proteins and inhibit cell wall synthesis (D)</p> Signup and view all the answers

What is the term for the process by which antibiotics are overprescribed and misused in farm animal feed?

<p>Antibiotic abuse (C)</p> Signup and view all the answers

Who is credited with the discovery of streptomycin?

<p>Selman Waksman (D)</p> Signup and view all the answers

What is the term for antibiotics that are effective against many species of bacteria?

<p>Broad spectrum (B)</p> Signup and view all the answers

What is the mechanism of action of quinolone antibiotics?

<p>They block bacterial DNA gyrase (C)</p> Signup and view all the answers

What is the term for the minimal concentration of an antibiotic that is lethal to a microorganism?

<p>Minimal lethal concentration (D)</p> Signup and view all the answers

What is the mechanism of action of sulfa drugs?

<p>They are analogs of PABA and prevent DNA synthesis (B)</p> Signup and view all the answers

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