Measures of Disease Frequency in Epidemiology
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Questions and Answers

What is the main focus of epidemiology?

  • Analyzing the economic factors affecting healthcare access
  • Studying the frequency and distribution of health-related states and events in human populations (correct)
  • Exploring the impact of climate change on health outcomes
  • Determining why diseases occur in specific populations

Which population type is defined by being in or out of a state?

  • Baby boomers
  • Dynamic population (correct)
  • Students in a school
  • Fixed population

What does a proportion involve dividing by?

  • The smaller of two quantities
  • The sum of itself with another quantity (correct)
  • The larger of two quantities
  • The product of two quantities

What does a rate measure in epidemiology?

<p>The occurrence of an event per population (B)</p> Signup and view all the answers

How is ratio different from proportion in epidemiology?

<p>Proportion involves dividing by another quantity, while ratio divides one quantity by another (B)</p> Signup and view all the answers

What does prevalence measure?

<p>How much disease is present in a population (D)</p> Signup and view all the answers

When is point prevalence calculated?

<p>At a specific moment in time (C)</p> Signup and view all the answers

What is period prevalence?

<p>A proportion within a range of time (D)</p> Signup and view all the answers

What is not useful for determining what caused the disease?

<p>Prevalence (A)</p> Signup and view all the answers

Why is prevalence information relevant for health service planning?

<p>To assess the burden of disease in populations (B)</p> Signup and view all the answers

Which measure is more accurate for exploring causes of a disease?

<p>Incidence Rate (C)</p> Signup and view all the answers

What does the Cumulative Incidence measure?

<p>New cases of a disease divided by the population at risk (A)</p> Signup and view all the answers

Why is Cumulative Incidence less accurate than Incidence Rate?

<p>It requires complete follow-up for all subjects (C)</p> Signup and view all the answers

Which population type is Incidence Rate more useful for?

<p>Dynamic populations (A)</p> Signup and view all the answers

What does Person-Time Rate involve?

<p>Accrual of total time in which subjects were at risk (D)</p> Signup and view all the answers

If incidence and cure rates are steady while treatment prolongs the life of individuals with a disease, what is the expected impact on prevalence?

<p>Increase (C)</p> Signup and view all the answers

In a fixed population with steady incidence and death rates, what happens to prevalence if the treatment cures the disease?

<p>Decrease (C)</p> Signup and view all the answers

What does the Mortality Rate measure?

<p>Proportion of deaths from a disease over total population (C)</p> Signup and view all the answers

Which rate is calculated as the proportion of cases of a disease without deaths divided by the total population?

<p>Morbidity Rate (C)</p> Signup and view all the answers

What does the Attack Rate measure?

<p>Proportion of exposed people developing a disease (B)</p> Signup and view all the answers

What is the purpose of Measures of Association in epidemiology?

<p>To determine the relationship between a disease and potential risk factors (A)</p> Signup and view all the answers

What is the Prevalence Ratio used for in epidemiological studies?

<p>To calculate the ratio of prevalence between exposed and unexposed groups (A)</p> Signup and view all the answers

In a 2x2 Table for Summarizing Epidemiological Data, what is typically compared?

<p>Whether or not people have the disease with whether or not people are exposed to a specific risk factor (B)</p> Signup and view all the answers

What does the Prevalence Ratio value of 2.85 indicate?

<p>There is a higher prevalence of the disease in the exposed group compared to the unexposed group (A)</p> Signup and view all the answers

What aspect of groups is compared when using Measures of Association?

<p>Exposure or characteristic (C)</p> Signup and view all the answers

What does a Rate Ratio (RR) less than 1.0 indicate?

<p>Negative association (C)</p> Signup and view all the answers

In epidemiological terms, what does a Rate Difference (RD) of 0 imply?

<p>No association between exposure and disease (A)</p> Signup and view all the answers

If the Rate Ratio (RR) is near 1.0, what does this suggest about the association?

<p>Weak association (C)</p> Signup and view all the answers

What does it signify if a Rate Difference (RD) is greater than 0?

<p>Positive association (B)</p> Signup and view all the answers

How is the Rate Ratio (RR) different from the Rate Difference (RD)?

<p>RR measures strength of association, while RD measures public health impact (A)</p> Signup and view all the answers

What does a Rate Difference (RD) less than 0 signify?

<p>Negative association (B)</p> Signup and view all the answers

What is the main purpose of Descriptive Studies in epidemiology?

<p>Generating hypotheses (B)</p> Signup and view all the answers

In Descriptive Studies, what is a major limitation that affects the ability to establish causal relationships?

<p>Inherent limitations in study design (A)</p> Signup and view all the answers

Which type of study design follows the results as they develop from present time forward?

<p>Prospective Studies (B)</p> Signup and view all the answers

What is a key advantage of Case Reports in epidemiology?

<p>Ease in generating a hypothesis (B)</p> Signup and view all the answers

When considering Individual studies, what is a significant disadvantage of Case Reports?

<p>They can't test a hypothesis (C)</p> Signup and view all the answers

What is a key advantage of a Case Series compared to Case Reports?

<p>Provides more evidence for hypotheses (A)</p> Signup and view all the answers

In a Cross-Sectional Study, what is a common limitation that makes it hard to establish causality?

<p>Hard to determine relationship between cause and effect (B)</p> Signup and view all the answers

What is a significant advantage of a Repeated Cross Sectional Study over a simple Cross-Sectional Study?

<p>Observes the same population at different moments in time (D)</p> Signup and view all the answers

Which of the following is NOT an advantage of a Cross-Sectional Study?

<p>Can establish causal relationships (B)</p> Signup and view all the answers

What is a primary disadvantage of a Case Series in terms of hypothesis testing?

<p>Cannot test a hypothesis (A)</p> Signup and view all the answers

Which of the following is an important use of a Cross-Sectional Study in epidemiology?

<p>Monitoring health status in a population (C)</p> Signup and view all the answers

What is a primary disadvantage of an Ecological Study?

<p>Tries to create facts about individuals through group results (C)</p> Signup and view all the answers

Why is it challenging to establish causality in an Ecological Study?

<p>It looks at aggregate data rather than individual-level data (A)</p> Signup and view all the answers

Which factor makes Ecological Studies susceptible to inaccurate associations?

<p>Uses aggregate data from a whole population (D)</p> Signup and view all the answers

What is a significant limitation of Ecological Studies in terms of association establishment?

<p>Dependence on group-level data rather than individual data (B)</p> Signup and view all the answers

Why do Ecological Studies struggle to ensure the exposure and disease development are linked in the same person?

<p>Inability to track individual-level information in aggregate analysis (D)</p> Signup and view all the answers

What type of study is indicated for diseases that take a long time to develop?

<p>Retrospective Study (D)</p> Signup and view all the answers

What measure can be used to assess the strength of the association between an exposed cohort and an unexposed cohort in a Longitudinal Study?

<p>Relative Risk (RR) (D)</p> Signup and view all the answers

Which type of Cohort Study involves exposure occurring before the disease and compares the disease development over time between exposed and unexposed cohorts?

<p>Prospective Study (A)</p> Signup and view all the answers

What is a common characteristic of Longitudinal Studies that makes them advantageous for certain types of diseases?

<p>Exposure preceding disease development (B)</p> Signup and view all the answers

Which characteristic of Ambi-Directional Studies makes them vulnerable to bias and limits their internal validity?

<p>Prospective and retrospective aspects (A)</p> Signup and view all the answers

What is an advantage of Cohort Studies when used to study multiple effects of exposure?

<p>Can establish causality (C)</p> Signup and view all the answers

What does an Odds Ratio (OR) value of 1.0 signify in a case-control study?

<p>No association between the exposure and the disease (D)</p> Signup and view all the answers

Which of the following is a disadvantage of a case-control study?

<p>Establishing causality (B)</p> Signup and view all the answers

In a case-control study, being unable to calculate cumulative incidence is primarily due to:

<p>Unattainable time at risk for cases (B)</p> Signup and view all the answers

Why are case-control studies not useful for rare exposures?

<p>Lack of statistical power (C)</p> Signup and view all the answers

What is a key advantage of using a control group in a case-control study?

<p>Balancing confounding variables (A)</p> Signup and view all the answers

If an Odds Ratio (OR) is significantly greater than 1.0, what interpretation can be made regarding the exposure and disease relationship?

<p>There is a causal relationship (C)</p> Signup and view all the answers

What is the primary purpose of random allocation in a Randomized Control Trial (RCT)?

<p>To minimize bias and eliminate selection bias (A)</p> Signup and view all the answers

Why is double-blinding considered the most preferred study design to establish causality in RCTs?

<p>It provides great internal validity by keeping both subjects and investigators unaware of group allocation (D)</p> Signup and view all the answers

What is the key advantage of maintaining frequent contact as a method to increase compliance in RCTs?

<p>It can enhance compliance by regularly engaging with study participants (D)</p> Signup and view all the answers

In what way does using a dispensing device contribute to increased compliance in RCTs?

<p>It guarantees that all participants receive the same treatment dose (C)</p> Signup and view all the answers

Why does noncompliance lead to inaccurate results in RCTs?

<p>Because it increases differences between groups and affects data analysis (C)</p> Signup and view all the answers

What is a significant disadvantage of randomization in RCTs?

<p>It increases internal validity but decreases external validity (B)</p> Signup and view all the answers

Which of the following is NOT a component of the evidence of causality in epidemiology?

<p>Cessation of Exposure (A)</p> Signup and view all the answers

If a study's findings cannot be replicated by independent investigators or in different populations, what aspect of evidence of causality is compromised?

<p>Replication of the Findings (B)</p> Signup and view all the answers

What does the term 'Specificity of the Association' imply in the context of determining causality?

<p>The exposure should have a specific effect on only one disease (D)</p> Signup and view all the answers

Why is biologic plausibility considered a crucial element in establishing causality in epidemiology?

<p>It provides a biological mechanism to explain the relationship between exposure and disease (A)</p> Signup and view all the answers

In epidemiology, what does the 'Dose-Response Relationship' indicate regarding exposure and disease?

<p>A stronger exposure is always associated with a higher risk of disease (C)</p> Signup and view all the answers

What distinguishes a Quasi-Experimental Study from an Experimental Study?

<p>It does not require random allocation. (B)</p> Signup and view all the answers

In a Posttest-Only with Control Group type of study, what differentiates group B from group A?

<p>Group B is analyzed after the intervention happens. (C)</p> Signup and view all the answers

What is a primary disadvantage of Natural Experiments compared to Randomized Control Trials (RCTs)?

<p>Natural Experiments struggle to rule out alternative explanations. (B)</p> Signup and view all the answers

What is the significance of a P-Value less than 0.05 in hypothesis testing?

<p>The results are considered statistically significant (D)</p> Signup and view all the answers

In hypothesis testing, what does it mean if a study has a P-Value greater than 0.05?

<p>The null hypothesis (H0) is accepted (C)</p> Signup and view all the answers

What are the disadvantages of using P-Value in hypothesis testing?

<p>Does not imply medical significance (C)</p> Signup and view all the answers

How can random error be reduced in a study?

<p>Increasing sample size and repeating the study (D)</p> Signup and view all the answers

What is the purpose of hypothesis testing in epidemiological studies?

<p>Determining the significance of random error (C)</p> Signup and view all the answers

Why is it important to understand that P-Value is probabilistic and not deterministic in hypothesis testing?

<p>To interpret results correctly (D)</p> Signup and view all the answers

What is a potential limitation related to the width of a Confidence Interval?

<p>Determines public health significance (B)</p> Signup and view all the answers

How can bias be avoided in research studies?

<p>Blinding (C)</p> Signup and view all the answers

What type of bias is created during the assembly process of placing subjects into groups?

<p>Selection Bias (A)</p> Signup and view all the answers

When is bias likely to occur during the research process?

<p>During the analysis stage (C)</p> Signup and view all the answers

What is the primary purpose of a Confidence Interval in epidemiological studies?

<p>To quantify random error (C)</p> Signup and view all the answers

What does it mean if a Confidence Interval includes the null value?

<p>The P-Value is Ӥ0.05 (C)</p> Signup and view all the answers

The Sensitivity of a screening test is calculated by:

<p>Dividing the true positive cases by the total amount of cases of the disease (D)</p> Signup and view all the answers

What is the primary reason why Sensitivity and Specificity are inversely proportional in screening tests?

<p>To maintain a balance between detecting true positives and true negatives (C)</p> Signup and view all the answers

Positive Predictive Value (PPV) in screening tests is defined as:

<p>The probability that a positive test result will be the disease (A)</p> Signup and view all the answers

What is Negative Predictive Value (NPV) in screening tests primarily based on?

<p>The probability that a negative test result will not be the disease (A)</p> Signup and view all the answers

What aspect of a disease does Detectable Pre-Clinical Phase (DPCP) aim to address?

<p>Diagnosis before symptoms develop (B)</p> Signup and view all the answers

In the context of screening tests, High Reliability refers to:

<p>The possibility of reproducible test results (A)</p> Signup and view all the answers

What is the primary purpose of Reflective Listening in patient interactions?

<p>To reinforce the patient's strengths and commend goals (D)</p> Signup and view all the answers

Which level of Reflective Listening involves the provider inferring the meaning and reflecting it back to the patient?

<p>Paraphrasing (A)</p> Signup and view all the answers

In Reflective Listening, what does 'Reflections of feeling' entail?

<p>Inferring and reflecting the implied meaning with emotional emphasis (A)</p> Signup and view all the answers

What is a common misconception about the Goals of Reflective Listening?

<p>It focuses on repeating what the patient says word for word (C)</p> Signup and view all the answers

How does Reflective Listening aim to diffuse resistance in patients?

<p>By emphasizing positive statements about change made by the patient (D)</p> Signup and view all the answers

What is a key element to consider in order for motivational interviewing to work effectively?

<p>Patient's ability to admit having a problem (A)</p> Signup and view all the answers

Which type of motivation is influenced by personal desires and those close to the patient?

<p>Intrinsic motivation (A)</p> Signup and view all the answers

What is one of the goals of eliciting permission, providing feedback in a non-threatening manner, and eliciting the person's interpretation in motivational interviewing?

<p>To keep the conversation non-threatening (D)</p> Signup and view all the answers

Which type of questions form the foundation of motivational interviews by encouraging open communication?

<p>Open-ended questions (A)</p> Signup and view all the answers

What should be avoided according to the principles of motivational interviewing?

<p>all of the above (D)</p> Signup and view all the answers

What characterizes a patient in the 'High Confidence' stage of change?

<p>Having a strong belief in the decision (D)</p> Signup and view all the answers

During the Clinical Discovery Phase of Community Water Fluoridation, why did Frederick McKay DDS find brown intrinsic teeth stains (mottled enamel)?

<p>Only in long-term residents of Colorado Springs (D)</p> Signup and view all the answers

What level of water fluoridation was determined as the balance between caries prevention and fluorosis during the Epidemiological Phase?

<p>0.7-1.2 ppm (A)</p> Signup and view all the answers

In what stage of change is a patient who is unsure of their decision to change or not change?

<p>Low Confidence (C)</p> Signup and view all the answers

What was the main source of the brown intrinsic teeth stains discovered by Frederick McKay DDS?

<p>Drinking water from deep artesian wells (A)</p> Signup and view all the answers

Which stage of change involves a patient who is stuck between wanting to change and not wanting to change?

<p>'Ambivalent' stage (A)</p> Signup and view all the answers

During the Clinical Discovery Phase, what type of residents did Frederick McKay DDS find to have brown intrinsic teeth stains due to mottled enamel?

<p>Long term residents (A)</p> Signup and view all the answers

In the Epidemiological Phase, what was the determined range of water fluoridation levels for the best balance between caries prevention and fluorosis?

<p>0.7-1.2 ppm (B)</p> Signup and view all the answers

What was the primary goal of the Demonstration Phase in conducting clinical trials in pairs of cities?

<p>To determine the results of water fluoridation (A)</p> Signup and view all the answers

What is considered one of the 10 great public health achievements of the 20th century according to the text?

<p>Water fluoridation (B)</p> Signup and view all the answers

Why was 0.7 ppm of fluoride determined as the balance for water fluoridation regardless of the ambient temperature zone?

<p>Toothpaste and mouthwash containing more fluoride (C)</p> Signup and view all the answers

What role did deep artesian wells play in causing mottled enamel according to Frederick McKay DDS?

<p>They contained high levels of fluoride (D)</p> Signup and view all the answers

What is the main difference between Topical [Post-Eruptive] Effects and Systemic [Pre-Eruptive] Effects of fluoride, as described in the text?

<p>Topical effects involve remineralizing tooth enamel, while systemic effects focus on making enamel resistant to demineralization (D)</p> Signup and view all the answers

What is the role of fluoride in tooth formation according to the Systemic [Pre-Eruptive] Effects concept?

<p>Fluoride is built into the enamel to resist demineralization (C)</p> Signup and view all the answers

What has been the general trend in tooth decay rates due to water fluoridation?

<p>Water fluoridation has led to a 25% reduction in tooth decay (C)</p> Signup and view all the answers

What is one potential danger highlighted in the text regarding fluoride toxicity?

<p>Fluoride toxicity can be achieved by ingesting excessive fluoridated water within a short time frame (B)</p> Signup and view all the answers

What is a major argument presented against community water fluoridation as discussed in the text?

<p>It is considered forced mass medication of the public (D)</p> Signup and view all the answers

What economic benefit does the text mention regarding savings from investing in fluoridation?

<p>$1 invested in fluoridation saves $38 in avoided dental treatment costs (A)</p> Signup and view all the answers

What is a major challenge faced by the Dental Care Delivery System's Safety Net System?

<p>Underfunding and limited capacity (C)</p> Signup and view all the answers

Which segment of the US population is mentioned to have the highest level of health disparities in terms of access to dental care?

<p>Hispanics (B)</p> Signup and view all the answers

What characterizes the Traditional Dental Workforce according to the information provided?

<p>Includes dental hygienists and laboratory technicians (D)</p> Signup and view all the answers

What is a significant advantage of the Private Practice Model in terms of payment methods?

<p>Diverse payment options including private insurance and out-of-pocket payments (D)</p> Signup and view all the answers

What is a critical need highlighted in the text that necessitates the existence of an Alternative Dental Workforce?

<p>Addressing the shortage of dentists in certain areas (B)</p> Signup and view all the answers

Why does the text emphasize the importance of the goal of health equity in relation to access to dental care?

<p>To address disparities and promote the highest level of health for all (A)</p> Signup and view all the answers

Which aspect of an association makes causality more likely according to the text?

<p>The strength of the association (C)</p> Signup and view all the answers

What did W. Hunter discover in 1911 regarding infections in the mouth?

<p>Infections in the mouth can cause problems in other parts of the body (A)</p> Signup and view all the answers

What is the primary benefit of nonsurgical periodontal therapy according to the text?

<p>No improvement in patient outcomes (B)</p> Signup and view all the answers

When considering causality, what should happen in relation to cause and effect?

<p>Cause should happen before the effect (C)</p> Signup and view all the answers

Which type of infection theory suggests that infections in the mouth can lead to problems in other parts of the body?

<p>Focal Infection Theory (A)</p> Signup and view all the answers

What is the association between periodontal disease and coronary heart disease based on studies?

<p>There is a proven link between periodontal disease and coronary heart disease (B)</p> Signup and view all the answers

Flashcards

Epidemiology

The study of disease frequency, distribution, and determinants in human populations.

Fixed Population

A group whose membership is permanent and defined by an event.

Dynamic Population

A group whose membership changes over time, defined by being in or out of a state.

Prevalence

Proportion of people with a disease at a point in time, compared to the total population.

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Point Prevalence

Prevalence at a specific moment in time.

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Period Prevalence

Prevalence within a specific time period.

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Incidence

Ratio of new cases of a disease, divided by the population at risk.

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Cumulative Incidence (CI)

Proportion of new cases within a time period, divided by population at risk at start.

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Incidence Rate (IR)

Proportion of new cases within a time period, divided by total person-time at risk.

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Person-time Rate

Measure of incidence that accounts for the time each person is at risk.

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2x2 Table

A table showing the comparison of disease presence and exposure to a risk factor.

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Prevalence Ratio

Ratio of prevalence between exposed and unexposed groups.

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Rate Ratio (RR)

Ratio of cumulative incidence in exposed and unexposed groups.

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Rate Difference (RD)

Difference in cumulative incidence in exposed and unexposed groups.

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Descriptive Studies

Studies used to generate hypotheses, describe observations, and serve as initial steps for analytical studies.

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Case Reports

Detailed reports of a single individual with a disease, identifying new diseases or risk factors.

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Case Series

Detailed reports on a group of individuals with similar diseases or problems.

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Cross-sectional study

Observational method assessing exposure and disease at a single point in time.

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Ecological study

Observe aggregate data from populations to look for correlations between exposures and disease occurrence.

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Study Notes

Measures of Disease Frequency

  • Epidemiology: the study of factors affecting health and illness in human populations, focusing on frequency, distribution, and determinants of health-related states and events.
  • Types of populations:
    • Fixed population: permanent membership, defined by an event (e.g. baby boomers)
    • Dynamic population: transient membership, defined by being in or out of a state (e.g. students in a school)

Disease Frequency

  • Prevalence: proportion of people with a disease at a point in time, divided by the total population
    • Types:
      • Point prevalence: proportion of people with a disease at a specific moment in time
      • Period prevalence: proportion of people with a disease within a range of time
  • Incidence: ratio of new cases of a disease, divided by the population at risk
    • Types:
      • Cumulative incidence (CI): proportion of new cases within a range of time, divided by the population at risk at the beginning
      • Incidence rate (IR): proportion of new cases within a range of time, divided by the total time each member of the population is at risk
    • Person-time rate: involves accruing total time each member of the population is at risk

Measures of Association

  • 2x2 table: comparison of disease presence and exposure to a risk factor
  • Prevalence ratio: ratio of prevalence between exposed and unexposed groups
  • Rate ratio (RR): ratio of cumulative incidence between exposed and unexposed groups, showing the strength of the association
  • Rate difference (RD): difference in cumulative incidence between exposed and unexposed groups, measuring public health impact

Study Designs

  • Descriptive studies: generate hypotheses, communicate clinical observations, and serve as the first step for analytical studies
    • Case reports: detailed report of a single case, identifying new diseases or risk factors
    • Case series: detailed report of a group of cases with similar problems
    • Cross-sectional studies: observe exposure and disease at a single point in time
    • Ecological studies: observe aggregate data from an entire population

Analytical Studies

  • Observational studies: test hypotheses, comparing groups, and observing what occurs naturally
    • Cohort studies: groups are determined by a common characteristic, and the development of disease is examined over time
    • Case-control studies: determine the differences between those with and without a disease, analyzing their exposure history
  • Experimental studies: healthy subjects are randomly placed into two groups, one exposed and one not, and followed to determine disease development
    • Randomized control trials (RCTs): the most preferred study design to establish causality, with high internal validity
      • Steps: enroll participants, random allocation, blinding, follow-up, and determine the outcome
    • Quasi-experimental studies: similar to experimental studies, but occur naturally, without random allocation
      • Types: posttest-only, pretest-posttest, and interrupted time series

Concepts of Studies

  • Validity:
    • Internal validity: determined by study design and analysis, confirming whether study conclusions reflect the study sample
    • External validity: determined by the applicability of study results to the larger population
  • Bias: any systematic error in the study design, data collection, or analysis that can lead to incorrect conclusions### Research Study Design
  • Reproducibility: determines if recreating the study will yield the same results
  • Causality: determines the association between the exposure and the disease
    • Works well for infectious diseases
    • Evidence of causality includes:
      • Relationship in time: exposure should come before the disease
      • Strength of association: calculate RR, RD, and OR to determine the association
      • Dose-response relationship: the stronger the exposure, the higher the yield of cases of disease
      • Replication of the findings: similar results should be reproducible with a similar study
      • Biologic plausibility: must make sense from a biologic point of view
      • Consideration of alternative explanations
      • Cessation of exposure
      • Specificity of the association
      • Consistency with other knowledge

Error in Research

  • Type 1 error (False Positive): observing a difference between groups that is not there
  • Type 2 error (False Negative): missing a difference between groups that is there
  • Sources of error:
    • Random error: false results derived from the observation of things that happened by chance
    • Reducing random error: increasing sample size, repeating the study and measurements, and hypothesis testing
    • P-Value: determines the probability of the results and H0 being related
      • If P-Value ≤ 0.05, then the results are considered statistically significant
      • If P-Value > 0.05, then the results are considered statistically insignificant
    • Disadvantages of P-Value:
      • Does not rule out bias
      • Does not rule out confounding
      • Does not imply medical significance
      • Does not imply biological significance
      • Does not imply public health significance
    • Confidence Intervals: involves a curve on a graph whose width determines the random error
      • Wide CI indicates high random error
      • Narrow CI indicates low random error

Screening for Disease

  • Detectable pre-clinical phase (DPCP): includes the time span after the disease is detectable by a screening and before symptoms develop
  • Characteristics of a good screening test:
    • Simple
    • Acceptable
    • Cheap
    • No risk of morbidity
    • High reliability
    • High validity
    • Test validity: ideally, sensitivity and specificity would each be 1.0
    • Sensitivity: probability that a diseased person will test positive
    • Specificity: probability that a non-diseased person will test negative
    • Positive predictive value (PPV): probability that a positive test will be the disease
    • Negative predictive value (NPV): probability that a negative test will not be the disease

Motivational Interviewing

  • Goal: build motivation for change and sustain that change over time
  • Patient-centered approach
  • Types of motivation:
    • Intrinsic: derived from personal desires
    • Extrinsic: influenced by the environment
  • Goals for health behavior change:
    • Treatment entry
    • Treatment adherence
    • Treatment engagement
    • Treatment response
    • Maintenance of treatment
  • OARS: open-ended questions, affirmations, reflective listening, and self-motivational statements
  • Levels of reflective listening:
    • Repeating
    • Rephrasing
    • Paraphrasing
    • Reflections of feeling
    • Complex reflections of meaning

Community Water Fluoridation

  • History:
    • Clinical discovery phase (1901-1933)
    • Epidemiological phase (1933-1945)
    • Demonstration phase (1945-1954)
    • Technology transfer phase (1950-present)
  • Mechanisms of action:
    • Topical [post-eruptive] effects
    • Systemic [pre-eruptive] effects
  • Safety and benefits:
    • Reduced tooth decay by at least 25%
    • Especially benefits children, the poor, and those with limited access to dental care
    • Provides overall decrease in oral health problems
  • Regulations:
    • Environment Protection Agency (EPA)
    • The Safe Drinking Water Act
    • FDA
    • DHHS
  • Fluoride toxicity:
    • Can be achieved by ingesting large amounts of fluoridated water
    • Babies and children are more susceptible to fluoride toxicity
  • Arguments against fluoridation:
    • Not FDA approved
    • No RCTs have been conducted
    • Considered a forced mass medication of the public
    • Fluoride used is not pharmaceutical quality
  • Savings:
    • $1 invested in fluoridation saves $38 in avoided costs for dental treatment
    • Average of $1 per person per year is spent on fluoridation

Access to Dental Care

  • Disparities:
    • Poor populations
    • Racial-ethnic minorities
    • Special needs individuals
    • Uninsured
    • Public insurance
    • Individuals living far from a dental practice
    • Fear of the dentist
    • Oral health ignorance
    • Not enough dentists in an area
  • Dental care delivery system:
    • Private practice model
    • Safety net system
    • Alternative dental workforce
  • Oral systemic disease associations:
    • Life in general is less satisfying due to condition of mouth and teeth
    • Oral health affects the quality of life
    • Physically, socially, and psychologically
  • Criteria for causality:
    • Strength
    • Consistency
    • Specificity
    • Temporality
    • Biological gradient
    • Plausibility

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Description

Explore the basics of epidemiology with a focus on measures of disease frequency. Learn about the importance of studying factors affecting the health and illness of human populations, including frequency, distribution, and determinants of health-related states and events. Understand the concepts of fixed and dynamic populations, along with the differences among ratio, proportion, and rate.

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