MCB 3020 General Microbiology Practice Test: Exams 3 and 4
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Questions and Answers

Which membrane of the host cell is involved in the formation of the envelope of herpes viruses?

  • Golgi apparatus
  • Mitochondrial
  • Plasma (correct)
  • Endoplasmic reticulum
  • What type of molecule is most commonly found on the surface of animal viruses for interacting with host cell receptors?

  • Glycolipid
  • Glycoprotein (correct)
  • Lipoprotein
  • Phospholipid
  • Which type of virus does not use RNA as its genome?

  • Poxvirus (correct)
  • Picornavirus
  • Rhabdovirus
  • Retrovirus
  • What is the term for a viral infection in which the virus remains dormant for a period before becoming active again?

    <p>Latent</p> Signup and view all the answers

    How does phage T4 protect its DNA from cleavage by host restriction enzymes?

    <p>By substituting glucosylated hydroxymethylcytosine for cytosine</p> Signup and view all the answers

    Is integration of the viral genome into the host chromosome required for lysogeny?

    <p>Always</p> Signup and view all the answers

    Which protein is required for the establishment and maintenance of lysogeny in cells infected with the temperate bacteriophage lambda?

    <p>Lambda repressor</p> Signup and view all the answers

    What is the term for the latent form of a bacteriophage genome that exists when a phage establishes lysogeny?

    <p>Prophage</p> Signup and view all the answers

    What type of bacteriophages only exhibit lytic replication cycles?

    <p>Virulent</p> Signup and view all the answers

    What is the characteristic of C.G+C content in the bacterial genome?

    <p>It is similar to the rest of the genome</p> Signup and view all the answers

    What is the primary function of the mucociliary escalator in the lungs?

    <p>To move trapped organisms away from the lungs by ciliary action</p> Signup and view all the answers

    What is the characteristic of the skin surface (epidermis) in relation to microorganisms?

    <p>It is a very favorable environment for colonization</p> Signup and view all the answers

    What is the characteristic of cervical mucus in relation to bacteria?

    <p>It has antibacterial activity</p> Signup and view all the answers

    What are pathogen-associated molecular patterns (PAMPs) examples of?

    <p>Lipopolysaccharide and peptidoglycan</p> Signup and view all the answers

    What is the function of the B subunit in AB toxins?

    <p>To bind to host cell receptors</p> Signup and view all the answers

    What is not a way in which fever augments the host's defenses?

    <p>Inhibition of growth by increasing the availability of iron</p> Signup and view all the answers

    What is the role of cytokines in the immune system?

    <p>They play key roles in both specific and non-specific immunity</p> Signup and view all the answers

    What is the characteristic of the replicative form of phage phiX174?

    <p>Direct the synthesis of minus-stranded DNA and plus-stranded DNA</p> Signup and view all the answers

    What is the primary function of turbulent airflow in the lungs?

    <p>To deposit airborne pathogens on sticky mucosal surfaces</p> Signup and view all the answers

    Which group of viruses is responsible for causing severe diarrhea, resulting in over 600,000 deaths worldwide annually?

    <p>Rotaviruses</p> Signup and view all the answers

    What is the characteristic of almost all known plant viruses?

    <p>They are RNA viruses</p> Signup and view all the answers

    For bacteriophage to be released from the host by a lysis mechanism, what is required?

    <p>Enzymes that damage the cell wall and cytoplasmic membrane</p> Signup and view all the answers

    What molecule must retroviruses first make in order to complete an infection?

    <p>dsDNA</p> Signup and view all the answers

    What is an organism that can cause disease in the host after direct interaction?

    <p>Primary pathogen</p> Signup and view all the answers

    What are inanimate materials involved in pathogen transmission called?

    <p>Fomites</p> Signup and view all the answers

    What does infection specifically refer to?

    <p>The multiplication of a pathogen on or within a host</p> Signup and view all the answers

    What are pathogenicity islands typically associated with?

    <p>Genes encoding rRNA</p> Signup and view all the answers

    What is the primary mode of transmission for Diphtheria?

    <p>Fecal-oral route</p> Signup and view all the answers

    A propagated epidemic is characterized by:

    <p>Person-to-person transmission</p> Signup and view all the answers

    What is the therapeutic dose of an antimicrobial drug?

    <p>The concentration that produces the desired clinical effect</p> Signup and view all the answers

    Which of the following statements is true about the minimal lethal concentration (MLC) of a drug?

    <p>It is the lowest concentration that kills a particular pathogen</p> Signup and view all the answers

    What is the primary mechanism of action of a bacteriostatic drug?

    <p>Inhibiting microbial growth</p> Signup and view all the answers

    What is the therapeutic index of a drug?

    <p>The ratio of the toxic dose to the therapeutic dose</p> Signup and view all the answers

    Which of the following is an example of a propagated epidemic?

    <p>Legionnaires' disease</p> Signup and view all the answers

    What is the primary mode of transmission for Lyme disease?

    <p>Vector-borne</p> Signup and view all the answers

    Which of the following statements is false about the formation of the envelope of herpes viruses?

    <p>The host cell nuclear membrane is involved in the formation of the envelope</p> Signup and view all the answers

    What is the term for the reactivated form of chickenpox?

    <p>Herpes zoster</p> Signup and view all the answers

    What is the primary location of Legionella pneumophila in the human body?

    <p>In alveolar macrophages</p> Signup and view all the answers

    What is the most likely cause of the rash associated with German measles?

    <p>An immunological reaction to the virus</p> Signup and view all the answers

    How is diphtheria typically treated?

    <p>With antitoxin and antibiotics</p> Signup and view all the answers

    What is the name of the small red lesions with a white center that form in the mouth and are associated with measles?

    <p>Koplik's spots</p> Signup and view all the answers

    Why is Legionnaires' disease named as such?

    <p>It was first identified at a convention of the American Legion</p> Signup and view all the answers

    What type of pathogens do not stimulate cell-mediated immunity as effectively as attenuated pathogens?

    <p>Inactivated pathogens</p> Signup and view all the answers

    What is the virus that causes chickenpox?

    <p>Varicella</p> Signup and view all the answers

    When is an infection considered nosocomial?

    <p>When it develops clinical symptoms during the patient's stay in a health care facility</p> Signup and view all the answers

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