Mastering CST

Which organ is responsible for the synthesis of corticosteroid hormones?

Kidneys

Liver

Adrenal gland (correct)

Pancreas

Which hormone is responsible for the maintenance of mineralocorticoid activity in adrenalectomized animals?

Androstenedione

Cortisol

DHEA

Aldosterone (correct)

Which protein is the major transport protein for corticosteroid hormones in the circulation?

Estrogen

Albumin

Transcortin

Corticosteroid-binding globulin (correct)

What is the half-life of cortisol in the circulation?

60-90 minutes Signup and view all the answers

Which hormones are produced by the adrenal cortex?

Glucocorticoids, mineralocorticoids, and androgens Signup and view all the answers

What is the primary function of glucocorticoids?

Raise blood glucose levels Signup and view all the answers

How is cholesterol transported into the mitochondria for steroid hormone synthesis?

By steroidogenic acute regulatory protein (StAR) Signup and view all the answers

Which enzyme converts angiotensinogen into angiotensin I?

Renin Signup and view all the answers

What is the primary effect of aldosterone on Na+ and K+?

Increases Na+ reabsorption and increases K+ excretion Signup and view all the answers

What is the main function of aldosterone?

Regulate electrolyte homeostasis Signup and view all the answers

What effect does cortisol have on muscle metabolism?

Decreases protein utilization Signup and view all the answers

How does cortisol affect fat metabolism during fasting?

Increases plasma fatty acids and glycerol levels Signup and view all the answers

What is one of the anti-inflammatory actions of cortisol?

Suppresses production of proinflammatory cytokines Signup and view all the answers

Which one of the following is NOT a functional zone of the adrenal glands?

Zona intermedia Signup and view all the answers

Which one of the following hormones is NOT secreted by the adrenal cortex?

Epinephrine Signup and view all the answers

Which one of the following describes the cellular mechanism of action of adrenal cortical hormones?

Direct entry into the nucleus Signup and view all the answers

Which one of the following is a consequence of chronic excess of glucocorticoids?

Hyperglycemia Signup and view all the answers

What is the main cause of Cushing's syndrome/disease?

Adenomas of the anterior pituitary that secrete large amounts of ACTH Signup and view all the answers

What is the effect of high doses of cortisol for an extended time?

All of the above Signup and view all the answers

Which of the following hormones increases tissue sensitivity to catecholamines?

Cortisol Signup and view all the answers

One physiological effect of cortisol is:

Stimulates glycogenolysis in the liver Signup and view all the answers

What is the effect of aldosterone?

Increases the ECF volume Signup and view all the answers

Which of the following hormones is NOT secreted from the adrenal cortex?

Testosterone Signup and view all the answers

Which of the following occurs during chronic excess of cortisol but not during acute stress response?

Increased insulin/glucagon ratio Signup and view all the answers

Which of the following is NOT a biological action of cortisol?

Lipid synthesis Signup and view all the answers

Mastering CST

Questions and Answers

Which organ is responsible for the synthesis of corticosteroid hormones?

Which hormone is responsible for the maintenance of mineralocorticoid activity in adrenalectomized animals?

Which protein is the major transport protein for corticosteroid hormones in the circulation?

What is the half-life of cortisol in the circulation?

Which hormones are produced by the adrenal cortex?

What is the primary function of glucocorticoids?

How is cholesterol transported into the mitochondria for steroid hormone synthesis?

Which enzyme converts angiotensinogen into angiotensin I?

What is the primary effect of aldosterone on Na+ and K+?

What is the main function of aldosterone?

What effect does cortisol have on muscle metabolism?

How does cortisol affect fat metabolism during fasting?

What is one of the anti-inflammatory actions of cortisol?

Which one of the following is NOT a functional zone of the adrenal glands?

Which one of the following hormones is NOT secreted by the adrenal cortex?

Which one of the following describes the cellular mechanism of action of adrenal cortical hormones?

Which one of the following is a consequence of chronic excess of glucocorticoids?

What is the main cause of Cushing's syndrome/disease?

What is the effect of high doses of cortisol for an extended time?

Which of the following hormones increases tissue sensitivity to catecholamines?

One physiological effect of cortisol is:

What is the effect of aldosterone?

Which of the following hormones is NOT secreted from the adrenal cortex?

Which of the following occurs during chronic excess of cortisol but not during acute stress response?

Which of the following is NOT a biological action of cortisol?

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