Mastering Aminoglycosides

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15 Questions

Which of the following is NOT a recommended use for aminoglycosides according to the text?

bacteremia/sepsis

Which aminoglycoside is commonly used as a secondary IV agent for tuberculosis?

Kanamycin

Which aminoglycoside has better anti-pseudomonal activity than gentamicin and amikacin?

Tobramycin

Which aminoglycoside is reserved for organisms resistant to other aminoglycosides?

Amikacin

Which aminoglycoside has a black box warning for teratogenicity in pregnancy?

Gentamicin

Which of the following is the mechanism of action for tetracyclines?

Binds to 30s ribosomal subunit

Which of the following adverse effects is associated with tetracyclines?

Liver toxicity

Which of the following antibiotics can be used for suppression therapy of methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA)?

Tetracyclines

Which antibiotic provides enhanced gram-negative coverage, covers vancomycin-resistant Enterococcus (VRE) and MRSA, but lacks coverage against Pseudomonas spp.?

Tigecycline

Which of the following is an adverse effect associated with minocycline?

Staining and deformity of the teeth

Which type of medications can increase neuromuscular blockade when used with aminoglycosides?

Loop diuretics

The aminoglycosides have excellent activity against which type of bacteria?

Aerobic

Aminoglycosides are used at synergistic doses along with cell wall active agents to treat which type of bacteria?

Gram-positive

What are the two major toxicities associated with the use of aminoglycosides?

Ototoxicity and nephrotoxicity

Which type of antibiotics can be inactivated by aminoglycosides?

Penicillin G

This quiz tests your knowledge of aminoglycosides, a type of antibiotic. You will learn about their mechanism of action, potential side effects, and important counseling points. Additionally, you will familiarize yourself with brand and generic names for these antimicrobial agents and understand their spectrum of activity. Get ready to test your knowledge on aminoglycosides!

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