Podcast
Questions and Answers
Which factor determines the loading dose of a drug?
Which factor determines the loading dose of a drug?
- Clearance
- Half-life (correct)
- Potency and efficacy
- Absorption and distribution
What may be a reason for adjusting the dose of a drug to maintain therapeutic concentration?
What may be a reason for adjusting the dose of a drug to maintain therapeutic concentration?
- Side effects
- Drug to drug interactions
- Dose-response relationships
- Therapeutic window (correct)
What does dosage refer to?
What does dosage refer to?
- The time it takes for a drug to reach steady state
- The prescribed amount of medicine over time (correct)
- The frequency of taking a drug
- The route of administration
Which type of protein mainly binds to basic drugs?
Which type of protein mainly binds to basic drugs?
Extensive protein binding slows drug elimination because...
Extensive protein binding slows drug elimination because...
What happens when the plasma is saturated with a drug?
What happens when the plasma is saturated with a drug?
Competition between drugs for protein binding sites can result in...
Competition between drugs for protein binding sites can result in...
Which of the following is true about the loading dose?
Which of the following is true about the loading dose?
What determines the maintenance dose of a drug?
What determines the maintenance dose of a drug?
What is the purpose of giving a drug multiple times during the day?
What is the purpose of giving a drug multiple times during the day?
What happens to plasma concentrations at steady state in normal kinetics?
What happens to plasma concentrations at steady state in normal kinetics?
What is the role of plasma protein binding in drug action?
What is the role of plasma protein binding in drug action?
Which factor affects the bioavailability of a drug?
Which factor affects the bioavailability of a drug?
What is the volume distribution of a drug?
What is the volume distribution of a drug?
Which factor can influence the onset of action of a drug?
Which factor can influence the onset of action of a drug?
Which route of administration allows a drug to enter circulation immediately?
Which route of administration allows a drug to enter circulation immediately?
What is the role of plasma in drug pharmacokinetics?
What is the role of plasma in drug pharmacokinetics?
Which type of drug primarily binds to plasma albumin?
Which type of drug primarily binds to plasma albumin?
What is the effect of extensive protein binding on drug elimination?
What is the effect of extensive protein binding on drug elimination?
What happens when the plasma is saturated with a drug?
What happens when the plasma is saturated with a drug?
What is the potential consequence of competition between drugs for protein binding sites?
What is the potential consequence of competition between drugs for protein binding sites?
Which plasma protein primarily binds to basic drugs?
Which plasma protein primarily binds to basic drugs?
Which factor can affect the bioavailability of a drug?
Which factor can affect the bioavailability of a drug?
Which factor determines the volume distribution of a drug?
Which factor determines the volume distribution of a drug?
Which factor can influence the onset of action of a drug?
Which factor can influence the onset of action of a drug?
Which factor is NOT related to the clinical factors affecting drug regimen?
Which factor is NOT related to the clinical factors affecting drug regimen?
Which factor can alter the bioavailability of a drug?
Which factor can alter the bioavailability of a drug?
Which of the following factors is NOT related to the determination of a drug regimen?
Which of the following factors is NOT related to the determination of a drug regimen?
What is the main purpose of a drug regimen in terms of drug concentration?
What is the main purpose of a drug regimen in terms of drug concentration?
Why is it important to escalate the dose of a drug in some cases?
Why is it important to escalate the dose of a drug in some cases?
What is the definition of dosage in the context of drug regimens?
What is the definition of dosage in the context of drug regimens?
Which of the following scenarios is undesirable in a drug regimen?
Which of the following scenarios is undesirable in a drug regimen?
Which of the following is true about the steady state concentration (Css) of a drug in normal kinetics?
Which of the following is true about the steady state concentration (Css) of a drug in normal kinetics?
What is the main difference between normal kinetics and saturation kinetics?
What is the main difference between normal kinetics and saturation kinetics?
What is the role of plasma protein binding in drug action?
What is the role of plasma protein binding in drug action?
What determines the loading dose of a drug?
What determines the loading dose of a drug?
What is the purpose of administering a loading dose of a drug?
What is the purpose of administering a loading dose of a drug?
What is the impact of extensive protein binding on drug elimination?
What is the impact of extensive protein binding on drug elimination?
Why does extensive protein binding slow drug elimination?
Why does extensive protein binding slow drug elimination?
What happens when the plasma is saturated with a drug?
What happens when the plasma is saturated with a drug?
What does increased free drug levels lead to?
What does increased free drug levels lead to?
Can competition between drugs for protein binding sites result in drug interactions?
Can competition between drugs for protein binding sites result in drug interactions?
Which plasma protein primarily binds to acidic drugs?
Which plasma protein primarily binds to acidic drugs?
Which plasma protein primarily binds to basic drugs?
Which plasma protein primarily binds to basic drugs?
What is the potential consequence of competition between drugs for protein binding sites?
What is the potential consequence of competition between drugs for protein binding sites?
What is the typical impact of drug interactions resulting from competition for protein binding sites?
What is the typical impact of drug interactions resulting from competition for protein binding sites?
Does increased free drug levels affect drug distribution, metabolization, or excretion?
Does increased free drug levels affect drug distribution, metabolization, or excretion?
