Master the Intricate Pathways of Blood Clotting

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Which of the following is a function of blood vessels and platelets in controlling bleeding?

Breaking down blood clots

Maintaining blood fluidity (correct)

Transporting oxygen to tissues

Producing coagulation factors

What are the factors involved in primary and secondary hemostasis?

Red blood cells and white blood cells

Platelets and coagulation factors (correct)

Enzymes and hormones

Hemoglobin and oxygen

What are the two pathways of the clotting cascade?

Arterial and venous

Primary and secondary

Extrinsic and intrinsic (correct)

Prothrombin and fibrinogen

How can clotting be stopped using drug therapy?

By inhibiting coagulation factors Signup and view all the answers

What can malfunction of hemostasis lead to?

Excessive bleeding Signup and view all the answers

What are the causes of hemostasis abnormalities?

Trauma and inflammation Signup and view all the answers

Which of the following is a function of platelets?

Liberate vasoconstrictors from granules Signup and view all the answers

What is the average lifespan of platelets in the circulation?

10 days Signup and view all the answers

What is the primary function of platelet plug formation?

To physically plug up damage in the endothelium Signup and view all the answers

Which of the following can lead to abnormal platelet function?

Leukemia Signup and view all the answers

What is the term for small red or red-blue spots about 1-5 mm in diameter indicative of defective or inadequate platelets?

Petechiae Signup and view all the answers

What can cause disturbances in coagulation?

All of the above Signup and view all the answers

Which pathway of blood coagulation is slower and takes 1-6 minutes for maintenance?

Intrinsic pathway Signup and view all the answers

What is the goal of both the intrinsic and extrinsic pathways of blood coagulation?

To activate thromboplastin Signup and view all the answers

What is the final product formed to create blood clots?

Fibrin Signup and view all the answers

What does thrombin do to fibrinogen to form fibrin?

Splits off a part of fibrinogen and forms smaller molecules Signup and view all the answers

Which coagulation inhibitors are necessary to counterbalance coagulation factors and restrict the clotting process to a limited area?

Antithrombin III, Protein C, and Protein S Signup and view all the answers

Which of the following is a symptom of Ebola virus infection?

All of the above Signup and view all the answers

What is the fatality rate of Marburg virus infection?

90% Signup and view all the answers

Which of the following laboratory tests measures the time it takes for blood plasma to clot after a lipid substance and calcium is added to the sample?

Partial thromboplastin time (PTT) Signup and view all the answers

What is the main function of cryoprecipitate in blood transfusion?

To provide clotting factors Signup and view all the answers

What is the characteristic feature of schistocytes in a blood smear?

Damaged blood cells Signup and view all the answers

Which of the following is a potential reservoir for Ebola virus?

Fruit bats Signup and view all the answers

Which of the following is a cause of coagulation disturbance?

Deficiency of plasma coagulation factors Signup and view all the answers

What is the role of vitamin K in the synthesis of coagulation factors?

It is required for the synthesis of most coagulation factors Signup and view all the answers

Which condition is characterized by clotting and fibrinolysis occurring at the same time?

Disseminated Intravascular Coagulation (DIC) Signup and view all the answers

What is the effect of a deficiency of VWF cleaving protein ADAMTS1?

Formation of large VWF multimer chains that criss-cross blood vessels Signup and view all the answers

Which of the following is a treatment option for Thrombotic Thrombocytopenic Purpura (TTP)?

Plasma exchange to remove VWF fragments Signup and view all the answers

Which of the following is a cause of coagulation disturbance associated with severe liver disease?