Master the Intricate Pathways of Blood Clotting
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Questions and Answers

Which of the following is a function of blood vessels and platelets in controlling bleeding?

  • Breaking down blood clots
  • Maintaining blood fluidity (correct)
  • Transporting oxygen to tissues
  • Producing coagulation factors

What are the factors involved in primary and secondary hemostasis?

  • Red blood cells and white blood cells
  • Platelets and coagulation factors (correct)
  • Enzymes and hormones
  • Hemoglobin and oxygen

What are the two pathways of the clotting cascade?

  • Arterial and venous
  • Primary and secondary
  • Extrinsic and intrinsic (correct)
  • Prothrombin and fibrinogen

How can clotting be stopped using drug therapy?

<p>By inhibiting coagulation factors (B)</p> Signup and view all the answers

What can malfunction of hemostasis lead to?

<p>Excessive bleeding (B)</p> Signup and view all the answers

What are the causes of hemostasis abnormalities?

<p>Trauma and inflammation (B)</p> Signup and view all the answers

Which of the following is a function of platelets?

<p>Liberate vasoconstrictors from granules (B)</p> Signup and view all the answers

What is the average lifespan of platelets in the circulation?

<p>10 days (C)</p> Signup and view all the answers

What is the primary function of platelet plug formation?

<p>To physically plug up damage in the endothelium (A)</p> Signup and view all the answers

Which of the following can lead to abnormal platelet function?

<p>Leukemia (C)</p> Signup and view all the answers

What is the term for small red or red-blue spots about 1-5 mm in diameter indicative of defective or inadequate platelets?

<p>Petechiae (D)</p> Signup and view all the answers

What can cause disturbances in coagulation?

<p>All of the above (D)</p> Signup and view all the answers

Which pathway of blood coagulation is slower and takes 1-6 minutes for maintenance?

<p>Intrinsic pathway (D)</p> Signup and view all the answers

What is the goal of both the intrinsic and extrinsic pathways of blood coagulation?

<p>To activate thromboplastin (B)</p> Signup and view all the answers

What is the final product formed to create blood clots?

<p>Fibrin (C)</p> Signup and view all the answers

What does thrombin do to fibrinogen to form fibrin?

<p>Splits off a part of fibrinogen and forms smaller molecules (B)</p> Signup and view all the answers

Which coagulation inhibitors are necessary to counterbalance coagulation factors and restrict the clotting process to a limited area?

<p>Antithrombin III, Protein C, and Protein S (A)</p> Signup and view all the answers

Which of the following is a symptom of Ebola virus infection?

<p>All of the above (D)</p> Signup and view all the answers

What is the fatality rate of Marburg virus infection?

<p>90% (B)</p> Signup and view all the answers

Which of the following laboratory tests measures the time it takes for blood plasma to clot after a lipid substance and calcium is added to the sample?

<p>Partial thromboplastin time (PTT) (C)</p> Signup and view all the answers

What is the main function of cryoprecipitate in blood transfusion?

<p>To provide clotting factors (C)</p> Signup and view all the answers

What is the characteristic feature of schistocytes in a blood smear?

<p>Damaged blood cells (A)</p> Signup and view all the answers

Which of the following is a potential reservoir for Ebola virus?

<p>Fruit bats (D)</p> Signup and view all the answers

Which of the following is a cause of coagulation disturbance?

<p>Deficiency of plasma coagulation factors (B)</p> Signup and view all the answers

What is the role of vitamin K in the synthesis of coagulation factors?

<p>It is required for the synthesis of most coagulation factors (A)</p> Signup and view all the answers

Which condition is characterized by clotting and fibrinolysis occurring at the same time?

<p>Disseminated Intravascular Coagulation (DIC) (B)</p> Signup and view all the answers

What is the effect of a deficiency of VWF cleaving protein ADAMTS1?

<p>Formation of large VWF multimer chains that criss-cross blood vessels (B)</p> Signup and view all the answers

Which of the following is a treatment option for Thrombotic Thrombocytopenic Purpura (TTP)?

<p>Plasma exchange to remove VWF fragments (D)</p> Signup and view all the answers

Which of the following is a cause of coagulation disturbance associated with severe liver disease?

<p>Deficiency of plasma coagulation factors (A)</p> Signup and view all the answers

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