15 Questions
What is the origin of macrophages?
Blood
Macrophages are involved in phagocytic activity.
True
What is the site of fixed macrophages?
Tissue (histiocytes)
Macrophages are involved in the removal of antigens through their __________ activity.
phagocytic
Match the following cell types with their characteristics:
Macrophage = Involved in phagocytic activity Mast Cell = Involved in allergic responses Adipocyte = Involved in fat storage Reticular Cell = Supports immune function
What is the characteristic of the cytoplasm of a Mast Cell?
Basophilic
A Mast Cell has a peripheral nucleus.
False
What is the name of the staining technique used to identify Mast Cells?
Metachromatic staining (toluidine blue)
Mast cells originate from the ______________ cells.
UMC
Match the following cell types with their characteristics:
Mast Cell = Granular, dark basophilic cytoplasm Adipocyte = Specialized for fat storage Reticular Cell = Found in connective tissue, produces fibers Macrophage = Phagocytic cell, engulfs foreign substances
What is the primary function of mast cells and basophils in the body?
To initiate allergy responses
Mast cells are a type of B cell.
False
What is the main function of histamine released by mast cells?
Vasodilation and smooth muscle contraction
Eosinophils are involved in the release of _______________, a chemotactic factor.
heparin
Match the following immune cells with their functions:
Mast cells = Initiate allergic responses Eosinophils = Produce antibodies Basophils = Release heparin Macrophages = Engulf foreign particles
Study Notes
Mast Cells
- Origin: UMC (Undifferentiated Mast Cells)
- Characteristics: large cell with granular, dark basophilic cytoplasm and central rounded pale nucleus
- Staining: metachromatic staining with toluidine blue
- Similarity: similar to basophils
- Function: initiate allergy response
- Release: histamine, leukotrienes, and other chemical mediators
- Effects: smooth muscle contraction, vasodilation
Eosinophils
- Origin: B-Cells (lymphocytes)
- Functions: secrete reticulin, support, phagocytic activity, and antigen presentation
- Anticoagulant: heparin secretion
- Chemotactic factor: attraction to specific sites
Macrophages
- Origin: blood monocyte
- Sites: fixed (tissue histiocytes) and free
- Functions: phagocytic activity, antigen presentation, and tissue repair
Learn about the characteristics, functions, and effects of mast cells and eosinophils in the immune system, including their roles in allergy response and inflammation.
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