Mast Cells and Eosinophils in Immunology
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Questions and Answers

What is the origin of macrophages?

  • Bone marrow
  • Spleen
  • Blood (correct)
  • Tissue

Macrophages are involved in phagocytic activity.

True (A)

What is the site of fixed macrophages?

Tissue (histiocytes)

Macrophages are involved in the removal of antigens through their __________ activity.

<p>phagocytic</p> Signup and view all the answers

Match the following cell types with their characteristics:

<p>Macrophage = Involved in phagocytic activity Mast Cell = Involved in allergic responses Adipocyte = Involved in fat storage Reticular Cell = Supports immune function</p> Signup and view all the answers

What is the characteristic of the cytoplasm of a Mast Cell?

<p>Basophilic (D)</p> Signup and view all the answers

A Mast Cell has a peripheral nucleus.

<p>False (B)</p> Signup and view all the answers

What is the name of the staining technique used to identify Mast Cells?

<p>Metachromatic staining (toluidine blue)</p> Signup and view all the answers

Mast cells originate from the ______________ cells.

<p>UMC</p> Signup and view all the answers

Match the following cell types with their characteristics:

<p>Mast Cell = Granular, dark basophilic cytoplasm Adipocyte = Specialized for fat storage Reticular Cell = Found in connective tissue, produces fibers Macrophage = Phagocytic cell, engulfs foreign substances</p> Signup and view all the answers

What is the primary function of mast cells and basophils in the body?

<p>To initiate allergy responses (C)</p> Signup and view all the answers

Mast cells are a type of B cell.

<p>False (B)</p> Signup and view all the answers

What is the main function of histamine released by mast cells?

<p>Vasodilation and smooth muscle contraction</p> Signup and view all the answers

Eosinophils are involved in the release of _______________, a chemotactic factor.

<p>heparin</p> Signup and view all the answers

Match the following immune cells with their functions:

<p>Mast cells = Initiate allergic responses Eosinophils = Produce antibodies Basophils = Release heparin Macrophages = Engulf foreign particles</p> Signup and view all the answers

Study Notes

Mast Cells

  • Origin: UMC (Undifferentiated Mast Cells)
  • Characteristics: large cell with granular, dark basophilic cytoplasm and central rounded pale nucleus
  • Staining: metachromatic staining with toluidine blue
  • Similarity: similar to basophils
  • Function: initiate allergy response
  • Release: histamine, leukotrienes, and other chemical mediators
  • Effects: smooth muscle contraction, vasodilation

Eosinophils

  • Origin: B-Cells (lymphocytes)
  • Functions: secrete reticulin, support, phagocytic activity, and antigen presentation
  • Anticoagulant: heparin secretion
  • Chemotactic factor: attraction to specific sites

Macrophages

  • Origin: blood monocyte
  • Sites: fixed (tissue histiocytes) and free
  • Functions: phagocytic activity, antigen presentation, and tissue repair

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Learn about the characteristics, functions, and effects of mast cells and eosinophils in the immune system, including their roles in allergy response and inflammation.

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