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Mast Cells and Eosinophils in Immunology

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Mast Cells and Eosinophils in Immunology

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Questions and Answers

What is the origin of macrophages?

Bone marrow

Spleen

Blood (correct)

Tissue

Macrophages are involved in phagocytic activity.

True

What is the site of fixed macrophages?

Tissue (histiocytes)

Macrophages are involved in the removal of antigens through their __________ activity.

phagocytic Signup and view all the answers

Match the following cell types with their characteristics:

Macrophage = Involved in phagocytic activity Mast Cell = Involved in allergic responses Adipocyte = Involved in fat storage Reticular Cell = Supports immune function Signup and view all the answers

What is the characteristic of the cytoplasm of a Mast Cell?

Basophilic Signup and view all the answers

A Mast Cell has a peripheral nucleus.

False Signup and view all the answers

What is the name of the staining technique used to identify Mast Cells?

Metachromatic staining (toluidine blue) Signup and view all the answers

Mast cells originate from the ______________ cells.

UMC Signup and view all the answers

Match the following cell types with their characteristics:

Mast Cell = Granular, dark basophilic cytoplasm Adipocyte = Specialized for fat storage Reticular Cell = Found in connective tissue, produces fibers Macrophage = Phagocytic cell, engulfs foreign substances Signup and view all the answers

What is the primary function of mast cells and basophils in the body?

To initiate allergy responses Signup and view all the answers

Mast cells are a type of B cell.

False Signup and view all the answers

What is the main function of histamine released by mast cells?

Vasodilation and smooth muscle contraction Signup and view all the answers

Eosinophils are involved in the release of _______________, a chemotactic factor.

heparin Signup and view all the answers

Match the following immune cells with their functions:

Mast cells = Initiate allergic responses Eosinophils = Produce antibodies Basophils = Release heparin Macrophages = Engulf foreign particles Signup and view all the answers

Study Notes

Mast Cells

Origin: UMC (Undifferentiated Mast Cells)
Characteristics: large cell with granular, dark basophilic cytoplasm and central rounded pale nucleus
Staining: metachromatic staining with toluidine blue
Similarity: similar to basophils
Function: initiate allergy response
Release: histamine, leukotrienes, and other chemical mediators
Effects: smooth muscle contraction, vasodilation

Eosinophils

Origin: B-Cells (lymphocytes)
Functions: secrete reticulin, support, phagocytic activity, and antigen presentation
Anticoagulant: heparin secretion
Chemotactic factor: attraction to specific sites

Macrophages

Origin: blood monocyte
Sites: fixed (tissue histiocytes) and free
Functions: phagocytic activity, antigen presentation, and tissue repair

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Description

Learn about the characteristics, functions, and effects of mast cells and eosinophils in the immune system, including their roles in allergy response and inflammation.